«Levofloxacin prophylaxis
during induction therapy for pediatric acute lymphoblastic leukemia»
The study was the largest yet focused on the safety and efficacy of proactive antibiotic therapy to prevent infections in pediatric ALL patients
during induction therapy.
Researchers reported that preventive therapy with levofloxacin or other antibiotics reduced the odds of infection, including fevers and bloodstream infections, by 70 percent or more in ALL patients with neutropenia
during induction therapy.
Not exact matches
While toxicity
during induction is still of concern, especially in the elderly patients, we conclude from these data that de-escalation of
induction therapy in elderly primary central nervous system lymphoma patients followed by maintenance treatment seems to be a promising treatment strategy.
The study showed that measuring MRD just twice
during remission
induction therapy — at day 19 and day 46 — rather than multiple times
during the more than two years of treatment was sufficient to guide treatment of most pediatric ALL patients.