One of the chemicals found in high levels in the blood of people experiencing
migraine is calcitonin gene - related peptide (CGRP), a neurotransmitter that is released from one nerve cell and activates the next one in a nerve tract
during an
attack.
There is INSUFFICIENT EVIDENCE about magnesium supplements effectiveness in preventing or treatment of anxiety [65], asthma (inhaled magnesium [12], attention deficit - hyperactivity disorder (ADHD)[35], cluster headache [13,53,54], chronic constipation [50], chronic fatigue syndrome (CFS)[61], depression [34], diabetes type 2 [56], fibromyalgia [60], heart
attack [70], high blood pressure [23], high blood pressure in pregnancy (pre-eclampsia)[67,68,69], kidney stones [11], leg muscle cramps in elderly or
during pregnancy [58,71],
migraine [52,54,64], multiple sclerosis (MS)[59], osteoporosis [1,2], premenstrual syndrome (PMS)[9,41], restless leg syndrome [57], tics (Tourette syndrome)[76] or stroke [2].
The study authors dismissed some of the potential reasons for
migraine remission
during the ketogenic periods, writing, «we attribute the improvement observed in these patients to ketogenesis, the sole event found to be time - locked to the disappearance (and recurrence) of their
migraine attacks.»