For example, using a transgenic marmoset model of Alzheimer's disease, clinicians and basic researchers are working together to identify the changes in the brain's circuitry
during mild cognitive impairment and very early stages of Alzheimer's.
Not exact matches
In a large population - based study of randomly selected participants in Germany, researchers found that
mild cognitive impairment (MCI) occurred significantly more often in individuals diagnosed with a lower ankle brachial index (ABI), which is a marker of generalized atherosclerosis and thus cumulative exposure to cardiovascular risk factors
during lifetime.
Conducting a cross-sectional study of a large cohort of patients with different levels of
cognitive impairment and different disease stages, the researchers found that the amounts of a TREM2 fragment in the cerebrospinal fluid were highest
during early stages characterized by
mild cognitive impairment symptoms.
Most of the players had suffered at least one concussion
during their careers, however, and athletes with three or more concussions were considerably more likely to have been diagnosed with
mild cognitive impairment — a condition that sometimes signals the approach of Alzheimer's disease.
During this time, 28 people developed Alzheimer's or
mild cognitive impairment, thought to be the earliest noticeable sign of several types of dementia, including Alzheimer's disease.
OBJECTIVE To use functional MRI (fMRI) to investigate whether hippocampal activation
during a memory task can predict
cognitive decline in individuals with
mild cognitive impairment (MCI).
Participants were divided into four groups: those diagnosed with probable Alzheimer's when entering the study, healthy controls with no sign of dementia, individuals with
mild cognitive impairment that remained stable over the two to three years for which scans were available, and those with
mild cognitive impairment that progressed to Alzheimer's disease
during the study.
During that time, 7.2 % of the men and 5.7 % of the women developed the mental - function problems known as
mild cognitive impairment (MCI), with or without any accompanying memory loss.
They used mass spectrometry to analyse the blood plasma of 53 participants with
mild cognitive impairment or Alzheimer's disease, including 18 who developed symptoms
during the study, and 53 who remained cognitively healthy.
In terms of an actual diagnosis of
mild cognitive impairment, however, the researchers only identified 37 people who developed that condition
during the study, and the diets didn't have a significant effect on the risk for that diagnosis.