LOCATING PRE-HEMATOPOIETIC STEM CELLS Researcher: Fuchou Tang, Assistant Professor, Biodynamic Optical Imaging Center, Integrated Science Research Center, Peking University Project: In a study published in Nature, Tang and his collaborators isolated pre-hematopoietic stem cells (HSCs) for the first time and showed their unique transcriptome signatures before and
during their maturation into HSCs (533:487 - 92, 2016).
Not exact matches
The colder waters
during a La Niña delay their
maturation and allow them to survive
into the next year, giving them a two - year life cycle.
To gain insight
into which mutations incurred
during affinity
maturation were responsible for the A14, B9 and B21 function, germ line reverted VHH (GL VHH) were recombinantly produced.
In the thymus, expression of CD4 and CD8 varies
during T cell
maturation, such that cells initially do not express CD4 or CD8 (double negative [DN]-RRB- after arriving to the thymus, then express both CD4 and CD8 (double positive [DP]-RRB- after TCR rearrangement, and finally downregulate either CD4 or CD8 to generate mature single - positive cells that exit
into the periphery.