Notch signaling coordinates cellular proliferation with differentiation
during zebrafish fin regeneration.
Elena Quesada Hernandez (Heisenberg, MPG)-- «The role of cell division orientation
during zebrafish early development» (2011)
A paper on the work, «Prostaglandin signaling regulates nephron segment patterning of renal progenitors
during zebrafish kidney development,» was published in the journal eLife this week.
When Kaufman, Zon and colleagues looked to see what was different about these early cancer cells, they found that crestin and the other activated genes are the same ones turned on
during zebrafish embryonic development — specifically, in the stem cells that give rise to the pigment cells known as melanocytes, within a structure called the neural crest.
«Thus, we hypothesize that Gdf3 combines with Ndr1 and Ndr2 to facilitate Nodal signaling
during zebrafish development, acting as an essential factor in embryonic patterning,» said Pelliccia, a graduate student in molecular biology.
Not exact matches
Groups of red and green labelled embryonic cells in a
zebrafish during their first migration in gastrulation.
In experiments on
zebrafish, Freiburg researchers have demonstrated that the same proteins that lead to the formation of metastases in humans also cause the cells to migrate
during embryonic development.
After following the fluctuations of these synapses over the course of a day, the team found that the
zebrafish did indeed have lower overall synapse activity
during sleep.
Building on the evidence that microglia were in play
during injury, the researchers conducted tests in
zebrafish with the specialized enzyme incorporated into both rod cells and microglial cells, removing both cell types to ask what role microglia play
during regeneration.
Conditioned
zebrafish treated with naloxone, a drug that blocks the μ - opioid receptor, as well as dopamine - or glutamate - blockers reduced their drug - seeking behavior
during the experiments.
For the first time, it is now found by a study that various mechanisms of transcribing DNA into RNA exist
during gene expression in the different development phases of
zebrafish.
But using a technique called calcium imaging, Aoki et al. were able to visualize for the first time the activity of the whole
zebrafish brain
during memory retrieval.
Researchers from Joaquín Rodríguez León's laboratory set out to analyze the contribution of different ion fluxes in the cell membrane, either inwards or outwards,
during regeneration in the
zebrafish caudal fin.
During the course, students collect
zebrafish embryos and watch them develop from single cells to swimming larvae complete with beating hearts and distinct pigmentation.
I am interested in applying fluorescence lifetime imaging microscopy (FLIM) to study the metabolic activity
during immune response to pancreatic cancer in a
zebrafish model.
In their study, to be published in the online edition of the Proceedings of the National Academy of Sciences
during the week of Jan. 26 - 30, researchers from Fukui Prefectural University in Obama, Japan, and the National Human Genome Research Institute (NHGRI), which is part of the National Institutes of Health (NIH), describe the innovative techniques they used to produce genetically modified
zebrafish using sperm cells grown under laboratory, or «in vitro,» conditions.
Here, the authors leveraged a
zebrafish model system to examine the role of that enhancer
during development.
We aim to comprehensively annotate functional elements, decipher genomic codes of transcription, as well as coding and non-coding gene function
during development and enhance
zebrafish as an attractive developmental, comparative and disease model.
Patricia Heyn (Neugebauer, MPG)-- «Nuclear architecture and gene expression
during early
zebrafish development» (2013)
Identification and Expression Analysis of
Zebrafish Glypicans
during Embryonic Development.
«
During heart regeneration in the
zebrafish we found that cardiomyocytes displayed structural changes similar to those observed in hibernating cardiomyocytes,» he said, noting that those changes were actually necessary before the fish cardiomyoctes could start dividing.
Lara Carvalho (Heisenberg, MPG)-- «The role of yolk syncytial layer in blastoderm movements
during gastrulation in
zebrafish» (2007)
Dorian Freudenreich (Brand, TUD)-- «Genetic cell lineage tracing and transcriptome analysis of neuronal progenitor cells
during neurogenesis and regeneration of the adult
zebrafish telencephalon» (2010)
Increased oxidative metabolism and myoglobin expression in
zebrafish muscle
during chronic hypoxia.
In particular we are interested to unravel the mechanisms that ensure the maintenance of the apical membrane when exposed to physical stress, e. g.
during morphogenesis of epithelial tissues, or when exposed to light stress in photoreceptor cells, using Drosophila and
zebrafish as model organisms.
Zebrafish colgate / hdac1 functions in the non-canonical Wnt pathway
during axial extension and in Wnt - independent branchiomotor neuron migration.
During his PhD he worked on three main projects: digital scanned laser light sheet fluorescence microscopy (with Dr. Ernst Stelzer), the in toto reconstruction of
zebrafish embryogenesis (with Dr. Jochen Wittbrodt), and the computational analysis of the evolution of the yeast genome architecture (with Dr. Michael Knop).
Whitehead Institute scientists have identified conserved, long intervening non-coding RNAs (lincRNAs) that play key roles
during brain development in
zebrafish, and went on to show that the human versions of these RNAs can substitute for the
zebrafish lincRNAs.
CAMBRIDGE, Mass. — Whitehead Institute scientists have identified conserved, long intervening non-coding RNAs (lincRNAs) that play key roles
during embryonic brain development in
zebrafish.
Now researchers at the Salk Institute for Biological Studies have identified an essential cellular pathway in
zebrafish that paves the way for limb regeneration by unlocking gene expression patterns last seen
during embryonic development.
In a report published on September 30 in Nature Genetics, Katsanis and his team used a small transparent fish,
zebrafish, to literally watch what happened if they chemically blocked the production of three proteins that are required for primary cilia function
during the period when a fish egg develops into a grown up, fully - finned fish.
The research lines of the Bakkers group include unraveling the genetics of normal cardiac development and body axis formation
during development, investigating the molecular mechanisms of heart regeneration in the
zebrafish and how this can be compared to heart injury in the mammals, and modeling of human (cardiac) disease in the
zebrafish to unravel biological mechanisms behind the disease and to identify new drug targets.
In addition to this, the gene duplicates in
zebrafish display strikingly different expression
during the day - night cycle, presumably to allow efficient regulation of photoreceptor cells under dramatically different light conditions.
The
zebrafish has a nearly transparent body
during early development, which provides unique visual access to the animal's internal anatomy.