Sentences with phrase «dying of cells in the brain»

Not exact matches

Unlike some of the promising treatments that have failed in 2017 that deal with the so - called «amyloid hypothesis» (the treatments target amyloid beta deposits in the brain that accumulate in people with Alzheimer's disease), approaches that try to prevent nerve cells from dying wouldn't have any impact on that buildup.

Most groups have focused on detecting proteins released from dying brain cells, but those proteins are not always abundant after injury and often require exotic or proprietary antibodies to measure, said study corresponding author Adam Chodobski, associate professor (research) of emergency medicine in the Alpert Medical School of Brown University.

These symptoms arise because nerve cells producing the neurotransmitter dopamine, located in an area of the brain known as the substantia nigra, slowly die.

«Amyloid is one of many substances that builds up in plaques as a result of dying cells and atrophy in the brain,» he says.

Svendsen is more optimistic about his team's work involving human tests of a novel stem cell approach to treat ALS, a degenerative motor neuron disease in which cells that transmit messages from the brain and spinal cord to the muscles wither or die.

The brains of the human babies with CHD that died in the first month of life also showed a depletion of neural precursor cells in the SVZ.

The tremors and other movement impairments of Parkinson's are triggered by the death of dopamine - producing cells in the brain, so the investigators used flies that had been genetically engineered to have their dopamine cells die off as they age.

And what happens in the fresh state is basically when respiration ends, when we stop breathing and we stop clearing toxins from cells, all those processes that were ongoing — and the cells don't know what yet, right; the rest of the body, the heart has stopped, the brain is stopping, but the cells still have some chemistry that's going on after the body has died.

They tested neural tissue from people who had died from Huntington's disease, a degenerative disorder of nerve cells in the base of the brain.

Last May in Nature Neuroscience, his lab and a team at Columbia University reported that embryonic stem cells could be used to shed light on the origins of amyotrophic lateral sclerosis (ALS), the progressive neurodegenerative disease in which motor neurons in the brain die.

The researchers hypothesize that guanabenz stimulates a protective cascade — because fewer oligodendrocytes die, less immune cells are recruited to the brain, which results in a decreased inflammatory response and preservation of myelin levels.

However, we can now use advanced computer simulations to challenge the existing paradigm and put forward a different theory about what actually takes place in the brain when the dopamine cells gradually die,» explains Jakob Kisbye Dreyer, Postdoc at the Department of Neuroscience and Pharmacology, University of Copenhagen.

He and his colleagues also reported that the improperly folded proteins found in the brains of Alzheimer's patients aren't what cause cells to die.

Working with the brains of six normal children and seven autistic children ages 2 to 16, most of whom died of drowning, Courchesne has studied neurons under the microscope and even counted the number of neural cells in different tissue samples.

In mice with a version of Alzheimer's, the antibodies make brain cells hyperactive, and the cells ultimately die.

Previously, Dr. Smeyne and his collaborator Dr. Stacey Schultz - Cherry in the Department of Infectious Disease at St. Jude Children's Research Hospital in Memphis, TN, showed that a deadly H5N1 strain of influenza (so - called Bird Flu) that has a high mortality rate (60 percent of those infected died from the disease) was able to infect nerve cells, travel to the brain, and cause inflammation that, the researchers showed, would later result in Parkinson's - like symptoms in mice.

Motor neuron disease (MND) is a group of diseases in which the nerve cells in the brain and spinal cord controlling the muscles that enable us to move, speak, breathe and swallow slowly degenerate and die.

«The activity of the microglia is stimulated by dying brain cells, not by the deposits of amyloid proteins, called plaques, which also occur in Alzheimer's disease,» Haass notes.

PDE10 is found almost exclusively in parts of the brain where brain cells die in HD.

Barcelona, studies the process by which stem cells turn into neurons, the type of brain cells that malfunction and die in HD.

This gene is used in every cell of a person's body, and yet HD occurs when specific brain cells dysfunction and, eventually, die.

And these essentially are toxic proteins that clog up the signaling of the areas in the brain so that cells essentially start to dysfunction and eventually to die off.

The mass die - off of nerve cells in the brains of people with Alzheimer's disease may largely occur because an entirely different class of brain cells, called microglia, begin to fall down on the job, according to a new study by researchers at the Stanford University School of Medicine.

By creating HD mice with glowing brain cells, researchers at the University of Nottingham Medical School and the Babraham Institute in the UK have found that some of the earliest changes happen before these cells start to die, in a region of the brain where HD researchers have never before thought to look.

But in bacteria - free mice, some of the animals» brain cells died.

For this study, they destroyed cells in the hippocampus, an area of the brain vital to memory formation and where neurons often die.

Over time, specific populations of cells in the brain become dysfunctional or die.

Carole Brody Fleet learned firsthand how financially devastating a spouse's death can be when her husband died of amyotrophic lateral sclerosis (ALS), a disease often referred to as Lou Gehrig's disease, that affects nerve cells in the brain and spinal cord.