Sentences with phrase «dynein moves»

Using this biologically accurate model of how dynein moves the microtubules within the axoneme, Ingber and Reilly created a short film called «The Beginning,» which draws parallels between sperm swimming toward an egg and spaceships flying toward a planet in space, giving an artistic bent to a scientific topic.

«The big questions now are, what is this dynein moving around, and how do the microtubules get oriented?»

Microtubules have plus and minus ends and researchers have observed dynein moving from the plus end to the minus.

Not exact matches

However, when they then «fixed» a specific hinge region of the dynein molecule that is known to connect dynein to its microtubule, they discovered that the dynein to spontaneously moved in its characteristic direction when force was applied at the ATP binding site, matching the way it moves in nature.

They found that this caused atoms in the entire protein to move in random directions when they performed their simulation of dynein floating in solution, as most conventional scientific simulations do.

The axoneme's movement is accomplished via rows of motor proteins called dyneins that are attached along the microtubules and exert force on them so the microtubules «slide» past each other, which then causes the entire axoneme and sperm tail to bend and move.

The film depicts several sperm attempting to fertilize the egg, «zooms in» on one sperm's tail to show how the dynein proteins move in sync to cause the tail to bend and flex, and ends with the sperm's successful journey into the egg and the initiation of cell division that will ultimately create a new organism.

The team found changes in a gene encoding a previously unknown «dynein,» a protein that moves like a railroad locomotive along cytoskeletal fibers called microtubules, hauling other molecules as cargo.

The base simulation will allow researchers to test more kinesins that move cargo from the nucleus to the outer limits of the cell and, eventually, dyneins, larger and more complex proteins that move cargo toward the center.

By combining many images of individual motors, we were able to sharpen up our picture of the dynein and build up a dynamic idea of how it moved.

Dr Burgess said: «During brain development, neurons must crawl into their correct position and dynein molecules in this instance grab hold of the nucleus and pull it along with the moving mass of the cell.

Dr Stan Burgess, at the University of Leeds» School of Molecular and Cellular Biology, who led the research team, said: «Dynein has two identical motors tied together and it moves along a molecular track called a microtubule.