Sentences with phrase «dyslipidemia in»

Tributyltin exposure induces gut microbiome dysbiosis with increased body weight gain and dyslipidemia in mice — Hao Guo — Environmental Toxicology and Pharmacology

Tributyltin exposure induces gut microbiome dysbiosis with increased body weight gain and dyslipidemia in mice

For example, high - fructose diets were shown to cause dyslipidemia in healthy people with and without a family history of type II diabetes, a recent study showed15.

She has published in scientific literature on several topics related to critical care medicine, including gunshot wounds, electrolyte derangements in diabetic ketoacidosis, and dyslipidemias in critically ill dogs.

Simple anthropometric measurements to predict dyslipidemias in Mexican school - age children: a cross-sectional study

Not exact matches

These findings — published in the June 2014 editions of Molecular Nutrition and Food Research — suggest this ingredient's use as a plausible tool in the comprehensive management of metabolic syndrome (MetS), which is defined as a cluster of heart attack and cardiovascular disease risk factors, including diabetes / prediabetes, abdominal obesity, dyslipidemia and hypertension.

The title of the study is: Polyphenols isolated from virgin coconut oil attenuate cadmium - induced dyslipidemia and oxidative stress due to their antioxidant properties and potential benefits on cardiovascular risk ratios in rats

This current study conducted in Nigeria looked at the pathogenic role of cadmium (Cd) and its exposure in the induction of dyslipidemia implicated in the development and increasing incidence of cardiovascular diseases, and explored whether polyphenolics isolated from virgin coconut oil (VCO) could prevent Cd - induced dyslipidemia.

Bioactive lipids in metabolic syndrome: Scientific literature review on dietary fats and oils that help with decreasing metabolic disorders such as abdominal obesity, dyslipidemia, hypertension and insulin sensitivity that increase risk of cardiovascular disease.

In mice, this form of lipodystrophy was also characterized by «whitening» of brown fat cells, a loss of white fat, and signs of metabolic syndrome, including insulin resistance, fat tissue inflammation, dyslipidemia (elevated cholesterol and fat), increased resting energy use, and increased markers of cardiovascular disease.

In earlier publications, the researchers analysed the effects of melatonin on obesity, dyslipidemia, high blood pressure and type 2 diabetes mellitus associated with obesity in young obese diabetic Zucker rats — an experimental model of metabolic syndromIn earlier publications, the researchers analysed the effects of melatonin on obesity, dyslipidemia, high blood pressure and type 2 diabetes mellitus associated with obesity in young obese diabetic Zucker rats — an experimental model of metabolic syndromin young obese diabetic Zucker rats — an experimental model of metabolic syndrome.

Sleeping in the dark and consuming these foodstuffs could help control weight gain and prevent cardiovascular diseases associated with obesity and dyslipidemia.

Previous studies had found that calcium scores were effective in predicting heart disease among adults with known heart disease risk factors, such as hypertension, diabetes, dyslipidemia, current smoking or a family history of heart disease.

NAFLD is an increasingly common condition in patients with obesity, type 2 diabetes, atherogenic dyslipidemia and arterial hypertension.

One of the greatest health concerns in developed countries is the increase in obesity, diabetes, and metabolic syndrome, which is a combination of high blood pressure (hypertension), blood sugar (hyperglycaemia), and cholesterol (dyslipidemia) along with increased belly fat.

The first suggestion of the possible benefits of cocoa came from epidemiologic studies conducted in Kuna Indians, an Amerind population living in the San Blas Island chain off the Coast of Panama that is known to have an extremely low prevalence of atherosclerotic disease, hypertension, diabetes, and dyslipidemia (14, 15).

Disruption of SEMA4D ameliorates platelet hypersensitivity in dyslipidemia and confers protection against the development of atherosclerosis.

Furthermore, the Dutch famine study population showed higher BMI and dyslipidemia only in women, which were exposed to food limitation (156).

As recently shown in a collaborative analysis of 10 large cohort studies, women appear to feature more often the metabolically healthy obese phenotype with normoglycemia and without dyslipidemia and hypertension (7 % — 28 %) compared with males (2 % — 19 %)(39).

Susan Amara, USA - «Regulation of transporter function and trafficking by amphetamines, Structure - function relationships in excitatory amino acid transporters (EAATs), Modulation of dopamine transporters (DAT) by GPCRs, Genetics and functional analyses of human trace amine receptors» Tom I. Bonner, USA (Past Core Member)- Genomics, G protein coupled receptors Michel Bouvier, Canada - Molecular Pharmacology of G protein - Coupled Receptors; Molecular mechanisms controlling the selectivity and efficacy of GPCR signalling Thomas Burris, USA - Nuclear Receptor Pharmacology and Drug Discovery William A. Catterall, USA (Past Core Member)- The Molecular Basis of Electrical Excitability Steven Charlton, UK - Molecular Pharmacology and Drug Discovery Moses Chao, USA - Mechanisms of Neurotophin Receptor Signaling Mark Coles, UK - Cellular differentiation, human embryonic stem cells, stromal cells, haematopoietic stem cells, organogenesis, lymphoid microenvironments, develomental immunology Steven L. Colletti, USA Graham L Collingridge, UK Philippe Delerive, France - Metabolic Research (diabetes, obesity, non-alcoholic fatty liver, cardio - vascular diseases, nuclear hormone receptor, GPCRs, kinases) Sir Colin T. Dollery, UK (Founder and Past Core Member) Richard M. Eglen, UK Stephen M. Foord, UK David Gloriam, Denmark - GPCRs, databases, computational drug design, orphan recetpors Gillian Gray, UK Debbie Hay, New Zealand - G protein - coupled receptors, peptide receptors, CGRP, Amylin, Adrenomedullin, Migraine, Diabetes / obesity Allyn C. Howlett, USA Franz Hofmann, Germany - Voltage dependent calcium channels and the positive inotropic effect of beta adrenergic stimulation; cardiovascular function of cGMP protein kinase Yu Huang, Hong Kong - Endothelial and Metabolic Dysfunction, and Novel Biomarkers in Diabetes, Hypertension, Dyslipidemia and Estrogen Deficiency, Endothelium - derived Contracting Factors in the Regulation of Vascular Tone, Adipose Tissue Regulation of Vascular Function in Obesity, Diabetes and Hypertension, Pharmacological Characterization of New Anti-diabetic and Anti-hypertensive Drugs, Hypotensive and antioxidant Actions of Biologically Active Components of Traditional Chinese Herbs and Natural Plants including Polypehnols and Ginsenosides Adriaan P. IJzerman, The Netherlands - G protein - coupled receptors; allosteric modulation; binding kinetics Michael F Jarvis, USA - Purines and Purinergic Receptors and Voltage-gated ion channel (sodium and calcium) pharmacology Pain mechanisms Research Reproducibility Bong - Kiun Kaang, Korea - G protein - coupled receptors; Glutamate receptors; Neuropsychiatric disorders Eamonn Kelly, Prof, UK - Molecular Pharmacology of G protein - coupled receptors, in particular opioid receptors, regulation of GPCRs by kinasis and arrestins Terry Kenakin, USA - Drug receptor pharmacodynamics, receptor theory Janos Kiss, Hungary - Neurodegenerative disorders, Alzheimer's disease Stefan Knapp, Germany - Rational design of highly selective inhibitors (so call chemical probes) targeting protein kinases as well as protein interaction inhibitors of the bromodomain family Andrew Knight, UK Chris Langmead, Australia - Drug discovery, GPCRs, neuroscience and analytical pharmacology Vincent Laudet, France (Past Core Member)- Evolution of the Nuclear Receptor / Ligand couple Margaret R. MacLean, UK - Serotonin, endothelin, estrogen, microRNAs and pulmonary hyperten Neil Marrion, UK - Calcium - activated potassium channels, neuronal excitability Fiona Marshall, UK - GPCR molecular pharmacology, structure and drug discovery Alistair Mathie, UK - Ion channel structure, function and regulation, pain and the nervous system Ian McGrath, UK - Adrenoceptors; autonomic transmission; vascular pharmacology Graeme Milligan, UK - Structure, function and regulation of G protein - coupled receptors Richard Neubig, USA (Past Core Member)- G protein signaling; academic drug discovery Stefan Offermanns, Germany - G protein - coupled receptors, vascular / metabolic signaling Richard Olsen, USA - Structure and function of GABA - A receptors; mode of action of GABAergic drugs including general anesthetics and ethanol Jean - Philippe Pin, France (Past Core Member)- GPCR - mGLuR - GABAB - structure function relationship - pharmacology - biophysics Helgi Schiöth, Sweden David Searls, USA - Bioinformatics Graeme Semple, USA - GPCR Medicinal Chemistry Patrick M. Sexton, Australia - G protein - coupled receptors Roland Staal, USA - Microglia and neuroinflammation in neuropathic pain and neurological disorders Bart Staels, France - Nuclear receptor signaling in metabolic and cardiovascular diseases Katerina Tiligada, Greece - Immunopharmacology, histamine, histamine receptors, hypersensitivity, drug allergy, inflammation Georg Terstappen, Germany - Drug discovery for neurodegenerative diseases with a focus on AD Mary Vore, USA - Activity and regulation of expression and function of the ATP - binding cassette (ABC) transporters

Since chia seeds have such high amounts of alpha - linoleic acid and dietary fiber, scientists have tried to find out how they can help with the prevention of metabolic conditions like dyslipidemia, which is the presence of extra fat in the blood and insulin resistance, the two key reasons for developing diabetes.

«Both groups improved dyslipidemia, with reduced circulating triglycerides, but showed differential responses in total and low - density lipoprotein cholesterol (decreased in LFHC group only), and high - density lipoprotein cholesterol (increased in VHFLC group only).»

In excess, however, cortisol promotes insulin resistance and many features of the metabolic syndrome (e.g., glucose intolerance, hypertension, dyslipidemia).

Also check cortisol levels; in excess, cortisol promotes insulin resistance and many features of the metabolic syndrome (e.g., glucose intolerance, hypertension, dyslipidemia).

In addition, more data are now available on the safety and efficiency of pharmacologic agents used to treat dyslipidemia.

Weight loss to lower elevated levels of total cholesterol, LDL - cholesterol, and triglycerides, and to raise low levels of HDL - cholesterol, in overweight and obese persons with dyslipidemia.

Inadequate dietary intake of methyl groups leads to hypomethylation in many important pathways, including 1) disturbed hepatic protein (methionine) metabolism as determined by elevated plasma homocysteine concentrations and decreased S - adenosylmethionine concentrations, and 2) inadequate hepatic fat metabolism, which leads to steatosis (fatty accumulation) and subsequent plasma dyslipidemia.

If serum cholesterol is healthiest below 160 mg / dl, then formula fed babies have excellent blood lipids despite a high disease and mortality rate, but breastfed babies are already in trouble at age one month and are suffering a shocking dyslipidemia at age six months, despite excellent health.

When mice being fed high - fat diets were also given anthocyanin extracts, researchers found that the polyphenols prevented both obesity and dyslipidemia, or abnormal levels of fats in the blood.

Ibanez L, Potau N, Marcos MV, de Zegher F. Treatment of Hirsutism, Hyperandrogenism, Gligomenorrhea, Dyslipidemia, and Hyperinsulinism in Nonobese, Adolescent Girls: Effect of Flutamide.

In rats moderate maternal dietary protein restriction is known to alter phenotypes in the offspring, which manifests as hypertension, dyslipidemia, and impaired glucose metabolisIn rats moderate maternal dietary protein restriction is known to alter phenotypes in the offspring, which manifests as hypertension, dyslipidemia, and impaired glucose metabolisin the offspring, which manifests as hypertension, dyslipidemia, and impaired glucose metabolism.

It makes sense to consider using berberine in patients with insulin resistance, pre-diabetes, diabetes, metabolic syndrome, hypertension, heart disease, dyslipidemia, cancer, depression, and other neuropsychiatric diseases.»

Numerous studies have shown that Chia seeds completely prevented the onset of dyslipidemia and insulin resistance, which are two factors in the development of diabetes.

When lipid levels in the bloodstream are too high or low, this condition is called dyslipidemia.

Dyslipidemia is common in women with PCOS.

It is associated with increased risk of Type 2 Diabetes Mellitus and abnormalities in blood lipid profile (dyslipidemias).

Other negative effects highlighted in the review include kidney stones (7 children developed stones) and dyslipidemia (total cholesterol as high as 383 mg / dl).

The present review will discuss the trends in fructose consumption, the metabolic consequences of increased fructose intake, and the molecular mechanisms leading to fructose - induced lipogenesis, insulin resistance and metabolic dyslipidemia.

The role of muscle insulin resistance in the pathogenesis of atherogenic dyslipidemia and nonalcoholic fatty liver disease associated with the metabolic syndrome.

For a large proportion of the population, however, the effect of higher - carbohydrate diets, particularly those enriched in refined carbohydrates, coupled with the rising incidence of overweight and obesity, creates a metabolic state that can favor a worsening of the atherogenic dyslipidemia that is characterized by elevated triglycerides, reduced HDL cholesterol, and increased concentrations of small, dense LDL particles (6, 7).

In contrast, recent evidence indicates that limitations in carbohydrate intake can improve all features of atherogenic dyslipidemiIn contrast, recent evidence indicates that limitations in carbohydrate intake can improve all features of atherogenic dyslipidemiin carbohydrate intake can improve all features of atherogenic dyslipidemia.

Cadmium concentrations in the kidney induce renal dysfunction and contribute to hypertension due to sodium retention, glucose intolerance, dyslipidemia and zinc deficiency.

Studies of atherogenic lipoprotein concentrations and properties have raised questions about the benefit of lowering saturated fat intakes by increasing carbohydrate intake, which can induce atherogenic dyslipidemia, and the benefit of increasing monounsaturated fat intakes, which does not lead to improvements in the properties of LDL particles that are associated with atherosclerosis in animal models, although substitution with monounsaturated fat rather than carbohydrate has been shown to reduce the ratio of total and LDL cholesterol to HDL cholesterol.

Sleeping in the dark and consuming these foodstuffs could help control weight gain and prevent cardiovascular diseases associated with obesity and dyslipidemia.

While we're still in American Heart Month, I figured I'd use my last Monday in February to talk about dyslipidemia!

First, depression has been linked to multiple biological abnormalities, including vascular pathologic changes, autonomic function changes, hypercoagulability, and hypothalamic - pituitary - adrenal axis hyperactivity.10 Evidence shows that depression in adulthood is linked to elevated risk of developing cardiovascular disease, diabetes, and dementia in later life.11 Second, inflammation contributes to atherosclerosis, insulin resistance, and neurodegeneration.12 - 14 Evidence shows that elevation in inflammation biomarkers, such as C - reactive protein (CRP), in adulthood predicts the development of cardiovascular disease, diabetes, and dementia in later life.15 - 17 Third, metabolic abnormalities such as obesity, dyslipidemia, glucose intolerance, hypertension, and cardiorespiratory fitness contribute to vascular lesions and hormonal imbalance.