Deletion of choline acetyltransferase in enteric neurons results in postnatal
intestinal dysmotility and dysbiosis — Carl D Johnson — The FASEB Journal
A randomised clinical trial comparing the efficacy of a herbal preparation STW 5 with the prokinetic drug cisapride in patients with
dysmotility type of functional dyspepsia.
In a prospective, randomized, double - blind, multi-center trial, this combination has also been shown to decrease the symptoms
of dysmotility type dyspepsia (indigestion) or essential / idiopathic dyspepsia in combination with IBS (Freise & Kohler, 1999).
With overuse, however, stimulant laxatives may damage the myenteric plexus and result in
colonic dysmotility.
Diabetic subjects may exhibit alterations of flavanol absorption due to diabetic autonomic neuropathy in different segments of the gastrointestinal tract, such as esophagus and
stomach dysmotility, delayed transit, and bacterial overgrowth (17).
Small
intestinal dysmotility, as evidenced by reduced migrating motor complex activity, is probably responsible for the prevalence of SIBO in elderly human patients.
[9] Jacobs, C., et al. «
Dysmotility and proton pump inhibitor use are independent risk factors for small intestinal bacterial and / or fungal overgrowth.»
Appropriately diagnosed and treated complex gastrointestinal diseases including but not limited to esophageal
dysmotility, gastroesophageal reflux, pancreatitis, pancreatic cystic lesions, inflammatory bowel disease, irritable bowel syndrome, and colorectal diseases