«We have seen SF3B1 mutation in chronic lymphocytic leukemia and in myeloid
dysplastic disorders, and now we show its importance in mucosal melanoma,» says Aik Choon Tan, PhD, investigator at the CU Cancer Center and associate professor of Bioinformatics at the CU School of Medicine.
These studies revealed that the void's physical characteristics — the type and location of missing bone — were consistent with a fibrous
dysplastic neoplasm, a tumor caused by a bone growth
disorder, the scientists report online today in PLOS ONE.