Primary analysis of the study showed that serelaxin
reduced dyspnoea and decreased 180 day mortality.
Patients with a poor diuretic response had
less dyspnoea relief (p = 0.0001) and a higher risk of cardiovascular death or rehospitalisation for heart failure or renal failure through day 60 (p < 0.004).
All dogs presented, since several months, recurrent chronic mucoid to muco - purulent nasal discharge, moist productive cough with episodes
of dyspnoea, hyperthermia and anorexia, resolving only transiently with various treatments (antibiotics, mucolytics, nebulization).
Respiratory symptoms (
including dyspnoea, asthma attacks, cough and sputum production) were assessed by physicians in the same season each year using a respiratory health questionnaire designed by the government of Japan.
These symptoms (sneezing, bilateral sero - mucous nasal discharge, productive cough, exercise intolerance,
dyspnoea, and lethargy) commonly appear at a very early age (i.e. weeks to months).