The progression of retinal dystrophy in the RCS rat is such that by 13 weeks post-graft most of the ONL has disappeared [33] and the photoreceptor outer segment layer is reduced to a debris zone [40], a finding we observed in
dystrophic controls.
Inset shows higher resolution confocal images of photoreceptor cell nuclear layers (DAPI blue) and rhodopsin expression (red) in
the dystrophic control (left inset) and dystrophic with iPS - RPE transplant (right inset) RCS rat.
Not exact matches
Four further
dystrophic and 4 non-
dystrophic (normal
control) rats remained as unoperated
controls.
Mean visual acuity (± S.E.M.) of the transplanted eye versus
control sham - injected eye and non-transplanted
dystrophic eye.