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Although the scope of this report allows only a targeted review of the
link between emotion regulation deficits and risk for comorbid psychopathology in adolescence, the extant literature indicates that emotion regulation is indeed a core transdiagnostic risk factor that represents
early embedded risk for the development of substance use, addiction, and comorbid psychopathology.
Shadur and Lejuez use two established developmental theories
linked to emerging substance use disorders, the externalizing pathway and the internalizing pathway, which together highlight how
early embedded risk in the form of emotion regulation deficits accounts for the development of addiction and comorbid psychiatric disorders.