I. Comparison of prepubertal, adolescent and
early adult onset forms
Not exact matches
Although juvenile glaucoma accounts for fewer than 1 % of all cases,
early indications are that mutations in the TIGR gene are behind at least 3 % of
adult -
onset cases as well.
The current study, involving 1153 alert
adult patients with acute sudden
onset headache admitted to 6 university - affiliated hospitals in Canada over 4 years from January 2010 to 2014, validates
earlier published research that initially proposed the Ottawa Subarachnoid Hemorrhage Rule.
Albertini replied that there might be subtle health effects, such as
early onset of
adult diseases like diabetes and cancer, that won't appear until 15 or 20 years after IVF, and he pointed out that there is very little follow - up data on the health of children created through assisted reproductive medicine.
«It would be worthwhile to examine these relationships among older adolescents and young
adults with food allergy who are at the peak of risk for depression
onset, especially because
early anxiety is associated with increased risk for subsequent
onset of depression,» said Jonathan Feldman, PhD, professor of Psychology at Ferkauf Graduate School of Psychology, Yeshiva University.
Having shorter telomeres is connected to the
early onset of illnesses such as cardiovascular disease and cancer, with mortality in older
adults and, as CMU's Sheldon Cohen first discovered, predicts susceptibility to acute infectious disease in young to midlife
adults.
Although many people think of Alzheimer's disease as something that only affects older
adults, there are actually two types of Alzheimer's disease: late
onset (also called typical) Alzheimer's which affects people over the age of 60 and
early onset Alzheimer's, which is defined by symptoms that begin before age 60.
The birth of new neurons in the mouse hippocampus starts waning in
early adulthood — well before cognitive decline becomes obvious — so the researchers wondered whether boosting Tet2 levels in the
adult hippocampus could restore neurogenesis and potentially prevent the
onset of cognitive decline later in life.
The least severe can be risk factors for
early adult -
onset degenerative diseases, such as osteoporosis and osteoarthritis.
The effect of intrauterine /
early life exposures on
adult onset cancers is an area of growing interest of Program members (Farzan, 2013).
In
early 2005, Michelle Begay, a Navajo, was well on her way to becoming one of the 27 percent of Native Americans in the southern U.S. who suffer from
adult -
onset diabetes.
An
early onset form of lysosomal storage disease, this can cause affected dogs to display neurologic signs as puppies or young
adults.
Developments Support Assistant — Client Side Exemplar Health Care are providers of nurse - led specialist care for
adults with complex needs, including neuro - disabilities, profound learning disabilities and autism, mental ill - health,
early -
onset dementia, brain injury and stroke.
Adolescence is a critical period for the development of depression with prevalence rates rising sharply from childhood to
early adulthood.1 Many
adult depressive disorders have their first
onset in adolescence2 with longer episode duration being the strongest predictor of future problems.3 In addition to increasing the risk of later mental health problems, adolescent depression is associated with significant educational and social impairment and is a major risk factor for suicide.1 Providing effective
early interventions to shorten the duration of episodes and potentially reduce the impact on later life is therefore important.3 This study explores this question and compares the effects of...
The second contrast tested the prediction that the
adult - depressed and never - depressed groups would not differ significantly on the
early childhood risk factors because the effects of childhood adversity on depression
onset decline with age.14 The third contrast compared the juvenile - depressed and juvenile /
adult — depressed groups on the
early childhood risk factors.
The
adult onset depression group did not differ from the
adult control group without depression in
early childhood risk factors except for being subjected to undesired sexual contact.
Jaffee SR, Moffitt TE, Caspi A, et al.Differences in
early childhood risk factors for juvenile -
onset and
adult -
onset depression.Arch Gen Psychiatry2002 Mar; 59:215 — 22OpenUrlCrossRefPubMedWeb of Science QUESTION: Are childhood biopsychosocial risk factors associated with juvenile
onset different from those associated with
adult onset major depressive disorder (MDD)?
A question for future research is whether risk factors exert their effects for only a limited period (suggesting that the same risk factors we measured in
early childhood, such as losing a parent, would predict
adult -
onset MDD if they occurred in late adolescence) or whether risk factors are developmentally sensitive, and those that predict juvenile -
onset MDD are qualitatively different from those that predict
adult -
onset MDD.
Early childhood risk factors differentiated juvenile
onset from
adult onset major depressive disorder
SEVERAL FINDINGS suggest that juvenile - and
adult -
onset major depressive disorder (MDD) have distinct origins.1 First, although a significant proportion of depressed children become depressed
adults, 2,3 most individuals who experience depression in adulthood were not depressed as children.4 Second, juvenile -
onset MDD is associated with increased risk for MDD among the first - degree relatives of depressed probands in clinical and community samples.4 - 8 Third, the children of depressed parents are at high risk for juvenile -
onset MDD compared with the children of nondepressed parents, and this association is explained by
early parental age at
onset of MDD.9
The juvenile - depressed group had a significantly
earlier age of MDD
onset (mean [SD], 12 [1.84] years) compared with the juvenile /
adult — depressed group (13 [1.47] years; t366 = 2.93; P ≤.01).
With the exception of having experienced unwanted sexual contact (which was measured retrospectively),
adult -
onset MDD does not seem to have an
early developmental diathesis.
That is, regardless of whether MDD persisted beyond childhood, the
early childhood risk factors distinguished the juvenile -
onset groups from the
adult -
onset group.
The findings differentiating juvenile - and
adult -
onset MDD are consistent with results from family studies, suggesting that juvenile -
onset MDD may be a distinct subtype associated with both genetic and
early childhood psychosocial risk factors.
However, depressed children and adolescents may also experience unique psychosocial risks, such as poor parenting or family discord, especially if these risks are genetically mediated.10, 11 Additional support for the hypothesis that juvenile - and
adult -
onset MDD are distinct subtypes would be demonstrated if
early childhood psychosocial risks were differentially associated with juvenile vs
adult -
onset MDD.
Jaffee SR, Moffitt TE, Caspi A, Fombonne E, Poulton R, Martin J. Differences in
Early Childhood Risk Factors for Juvenile -
Onset and
Adult -
Onset Depression.
This finding calls for renewed vigor in the search for adolescent and
early -
adult life events that trigger
adult -
onset MDD.
These findings replicate and extend the work of Kessler and Magee14 by showing that
early childhood risks differentiate juvenile from
adult -
onset cases.
Adult onset of major depressive disorder in relation to
early life violent victimisation: a case - control study
Hypotheses are assessed using logistic regression models predicting the odds of
early onset of sexual intercourse among 9959 respondents (53 % female, 47 % male) from the National Longitudinal Study of Adolescent to
Adult Health.
The resulting stress trajectories may include the
early onset of puberty (Ge et al. 2001), adolescent stressful life events and circumstances (Wickrama et al. 2015b), romantic relationship problems (Barr et al. 2016), and an off - time (
early or late) transition to adulthood, including the acquisition of
adult roles such as becoming a parent, cohabiting, and dropping out of school (Lee 2015; Wickrama et al. 2015a, 2005).
Adolescent -
onset alcohol abuse exacerbates the influence of childhood conduct disorder on late adolescent and
early adult antisocial behaviour.
Psychiatric comorbidities of
adults with
early - and late -
onset attention - deficit / hyperactivity disorder.
There is limited evidence on which children have problems that are likely to persist and which will improve; children who desist from
early conduct problems and those with
onset in adolescence are also vulnerable as
adults.