Sentences with phrase «early clinical studies»

Early clinical studies in 1998 by Dr. Bruce Grahn at the University of Saskatchewan, Canada, first described CMR in the Great Pyrenees.

As the Global HIV Vaccine Product Manager for the US Army, Dr. Ake advances the development of HIV vaccine candidates in preclinical and early clinical studies.

Previous studies from the laboratory of Daniel B. F. Saris (University Medical Center Utrecht, The Netherlands) reported that a novel stem cell combination represented a safe and efficient means to repair cartilage in preclinical [1] and early clinical studies [2].

First of all, early clinical studies of MSCs involved small numbers of cells manufactured for a small numbers of patients.

1) The earliest clinical study that we know of on progesterone and breast cancer was done at Johns Hopkins University back in 1981 (Cowan et al, American Journal of Epidemiology).

Not exact matches

Many people believe that eating early in the morning will jumpstart your metabolism or that eating late at night will widen your waist because it's already asleep, but this study from the American Journal of Clinical Nutrition concluded that's a false claim.

Earlier this month, the Journal of Allergy and Clinical Immunology published a study estimating that 2.5 % of Americans have a food allergy.

An early, outsourced clinical research study with real patients was encouraging, but there are many potential pitfalls yet to come, said University of North Carolina diabetes researcher Dr. John Buse, who was briefed by Google on the lens last week.

In early September, Alnylam stopped giving doses of its fitusiran drug for a rare bleeding disorder to patients enrolled in clinical studies after the death of a patient.

Sad news from the halls of research today, in which a study published in the American Journal of Clinical Nutrition says that eating fried potatoes two or more times a week can double your risk of early death.

Two earlier peer - reviewed studies published in the American Journal of Clinical Nutrition by researchers from the University of North Carolina in 2012 and 2013 randomly assigned non-dieting participants to drink either water or diet beverages.

Don't Start Too Early «The idea that parents should hurry reading, spelling, writing, or math ahead of children's normal development is not supported by a single replicable research study in the world or by any clinical experience in history...» - so read this to find out what you should do, when and how to start.

and MFT Clinical Interns observing for their studies in child development and early attachment.

A recent study in the American Journal of Clinical Nutrition lends support to this line of thinking, whereby researchers observed that excessive amounts of nutrition early in life are associated with being overweight later in life.

While the theoretical principles guiding the use of the NBO and the accompanying training program, include many of the conceptual themes that informed our work with the NBAS, they are influenced by theoretical and clinical principles from the fields of infant mental health, child development, brain development, behavioral pediatrics, systems theory, communication studies, nursing, early intervention and cultural studies, among its influences.

The authors of the study recognise the risks associated with an elective caesarean, and decisions about subsequent mode of delivery in women who had a severe perineal tear in an earlier pregnancy must be weighed against the clinical and psychological impacts of severe perineal tearing.

The PhD course focuses on various aspects of human (donor) milk, with as main study a randomized clinical trial towards the effects of human donor milk in very low birth weight infants (the Early Nutrition Ststudy a randomized clinical trial towards the effects of human donor milk in very low birth weight infants (the Early Nutrition StudyStudy).

Several years ago, in a clinical study comprising 400 newborns, Dr Ola Andersson and colleagues demonstrated that the risk of iron deficiency at the age of four months was considerably lower in infants whose umbilical cords were clamped and cut three minutes after birth («delayed cord clamping», DCC) than in those whose cords were removed within ten seconds («early cord clamping», ECC).

Although some SIDS experts and policy - makers endorse pacifier use recommendations that are similar to those of the AAP, 272,273 concerns about possible deleterious effects of pacifier use have prevented others from making a recommendation for pacifier use as a risk reduction strategy.274 Although several observational studies275, — , 277 have found a correlation between pacifiers and reduced breastfeeding duration, the results of well - designed randomized clinical trials indicated that pacifiers do not seem to cause shortened breastfeeding duration for term and preterm infants.278, 279 The authors of 1 study reported a small deleterious effect of early pacifier introduction (2 — 5 days after birth) on exclusive breastfeeding at 1 month of age and on overall breastfeeding duration (defined as any breastfeeding), but early pacifier use did not adversely affect exclusive breastfeeding duration.

He cautions, however, about drawing too many conclusions from animal studies and early - stage clinical trials.

But a blood test could help researchers more easily identify people who might be good candidates for clinical trials of early interventions, says Steven Kiddle, a biostatistician at the University of Cambridge, who wasn't part of either study.

The findings of the experimental study, presented in the most recent issue of the American Journal of Clinical Nutrition, suggest that improving maternal DHA nutrition has a favorable programming effect on the fetus that influences body composition in early childhood.

It could also identify those patients with early signs of autoimmunity who might be good candidates for clinical research studies.

Now a University of Colorado Cancer Center study published online ahead of print in the journal Oncogene offers compelling evidence explaining this failure and offering a possible strategy for the use of retinoic acid or other retinoids against some breast cancers: Because early clinical trials are often offered to patients who have already tried other more established therapies, breast cancer cells may have been pushed past an important tipping point that offers retinoic acid resistance.

The study appears this week in the early online edition of the Journal of Clinical Oncology, a peer - reviewed journal of the American Society of Clinical Oncology.

In a study published in Clinical Gastroenterology and Hepatology, Saint Louis University researchers have found a link between acute pancreatitis (inflammation of the pancreas) and pancreatic cancer, a finding which may eventually lead to some pancreatic cancers being detected earlier.

«In an earlier phase I clinical study, our group has shown that increasing the dose of radiation delivered daily with high precision and using image guidance may offset the need for chemotherapy in improving survival, and it may also improve quality of life measures by reducing treatment periods in half.

The neuroprotective effects of nicotine were studied in a randomized clinical trial involving 67 subjects in the early stages of Alzheimer's disease, where memory was slightly impaired but decision - making and other cognitive abilities remained intact.

Plus, he points to two clinical studies that have shown that the fever - reducer acetaminophen — commonly known as Tylenol — decreased fever - associated birth defects, and he suggests that doctors and patients consider the drug's use to treat fevers early in pregnancy.

Weiss cautioned that this proof - of - principle finding is an early step, with many further studies to be done to verify if this approach will be safe and effective in clinical use.

Researchers derived data from the Harvard Aging Brain Study, an observational study of older adult volunteers aimed at defining neurobiological and clinical changes in early Alzheimer's disStudy, an observational study of older adult volunteers aimed at defining neurobiological and clinical changes in early Alzheimer's disstudy of older adult volunteers aimed at defining neurobiological and clinical changes in early Alzheimer's disease.

A somewhat obscure study on statistical methods published in 2009 by medical statistician Ying Lu at Stanford University, California in a specialty journal on clinical trials, was downloaded 2000 times in early August, making it the hottest paper among Stanford University's 5439 registered users.

An early - stage clinical study by another institution, published in the Lancet Oncology in May 2016, combined chemotherapy with an experimental drug that blocks CCR2, a receptor on monocytes and macrophages whose activation stimulates these cells to infiltrate tumors.

The new Sierra Leone findings, published in Clinical Infectious Diseases, are similar to those seen in another study of Ebola survivors in Guinea during this outbreak and to earlier anecdotal or official reports of health issues among survivors of earlier flare - ups.

Earlier peer - reviewed articles from the study have appeared in the American Journal of Clinical Nutrition, BMC Nutrition, and Appetite.

«While this study took place in mice, the work sets the scene to do early clinical trials in humans.

With the initial contract of $ 24.9 million over the next 18 months, Mapp Pharmaceutical will manufacture a small amount of the drug for early - stage clinical studies to demonstrate its safety and efficacy in people.

The clear result of this clinical study — that the combination reduced strokes, heart attacks and cardiovascular death by practically 25 per cent compared to either drug alone in both patients with stable coronary or peripheral artery disease — caused the clinical trial to be stopped early, after 23 months, in February 2017.

The lead researcher for the study, Professor Gita Mishra, Professor of Life Course Epidemiology and Director of the Australian Longitudinal Study on Women's Health at the University of Queensland, Australia, said: «If the findings from our study were incorporated into clinical guidelines for advising childless women from around the age of 35 years who had their first period aged 11 or younger, clinicians could gain valuable time to prepare these women for the possibility of premature or early menopstudy, Professor Gita Mishra, Professor of Life Course Epidemiology and Director of the Australian Longitudinal Study on Women's Health at the University of Queensland, Australia, said: «If the findings from our study were incorporated into clinical guidelines for advising childless women from around the age of 35 years who had their first period aged 11 or younger, clinicians could gain valuable time to prepare these women for the possibility of premature or early menopStudy on Women's Health at the University of Queensland, Australia, said: «If the findings from our study were incorporated into clinical guidelines for advising childless women from around the age of 35 years who had their first period aged 11 or younger, clinicians could gain valuable time to prepare these women for the possibility of premature or early menopstudy were incorporated into clinical guidelines for advising childless women from around the age of 35 years who had their first period aged 11 or younger, clinicians could gain valuable time to prepare these women for the possibility of premature or early menopause.

The study divides 177 blood and 27 post-mortem brain samples into several groups, establishing that careful analysis of RNA transcripts in blood samples has the ability to distinguish early clinical AD, Parkinson's disease (PD), and cognitively healthy patients.

«The compelling results seen in this global study provide unequivocal evidence supporting the clinical utility of Oncotype DX to risk - stratify patients with early stage breast cancer, and indicate that the findings are generalizable to everyday clinical practice,» said lead author Joseph A. Sparano, MD, vice-chairman of medical oncology at Montefiore Einstein Center for Cancer Care, and professor of medicine and of obstetrics, gynecology, women's health at Albert Einstein College of Medicine.

The Swiss - based pharmaceutical company said that it had made 10 liters of vaccine that it will use in pre-clinical studies and maybe early clinical trials.

White and colleagues will work with other collaborators at the Cancer Institute to develop early - phase patient clinical trials based on the findings from this study in the near future.

In the 1980s, both US - based and international randomized clinical studies found that BCT and mastectomy offered women with early stage breast cancer equal survival benefit.

«Clinical studies are starting to show that adolescents who drink early and consistently across the college years have some deficits in learning and memory,» said senior author Scott Swartzwelder, Ph.D., professor in psychiatry at Duke.

A 2010 study by William Jarrold, a cognitive scientist at the University of California, Davis, suggests that an automated system that analyzes speech patterns on phone calls can potentially pick up on cognitive impairment and clinical depression or determine if someone is in the very early stages of Alzheimer's.

Although this study is limited by the lack of data on the effects of clinical interventions and neonatal resuscitation efforts that may have been performed at the time of birth, these findings suggest that early detection of perinatal asphyxia is particularly relevant among infants of overweight and obese women although more studies are necessary to confirm these results in other populations.

«It is still early days but the study, which was funded through an NIHR Clinical Lecturer grant and a College of Emergency Medicine Research Grant, could potentially make a huge difference to large numbers of patients.

Such claims could lead to confusion for consumers as early clinical and epidemiological studies report conflicting or confusing results.

ESDM is the first early intervention for toddlers with ASD to undergo controlled clinical study of intensive early intervention and has demonstrated both improvement of social skills and brain responses to social stimuli.