Sentences with phrase «early clinical trial design»

Phase I trial - an early clinical trial designed to study an experimental vaccine in humans.

Not exact matches

Although some SIDS experts and policy - makers endorse pacifier use recommendations that are similar to those of the AAP, 272,273 concerns about possible deleterious effects of pacifier use have prevented others from making a recommendation for pacifier use as a risk reduction strategy.274 Although several observational studies275, — , 277 have found a correlation between pacifiers and reduced breastfeeding duration, the results of well - designed randomized clinical trials indicated that pacifiers do not seem to cause shortened breastfeeding duration for term and preterm infants.278, 279 The authors of 1 study reported a small deleterious effect of early pacifier introduction (2 — 5 days after birth) on exclusive breastfeeding at 1 month of age and on overall breastfeeding duration (defined as any breastfeeding), but early pacifier use did not adversely affect exclusive breastfeeding duration.

«Part of what was exciting about the design of this clinical trial is that we decided early on to accept women from a younger and generally sicker population than is typically enrolled in clinical trials,» says Dr. Cristofanilli, who is also a researcher at the Sidney Kimmel Cancer Center at Thomas Jefferson University.

Appel and Sacks led three earlier clinical trials that tested ways to reduce the risk of cardiovascular disease and diabetes, providing volunteers with carefully designed diets and measuring the effects on key health indicators.

Early anti-pseudomonal acquisition in young patients with cystic fibrosis: rationale and design of the EPIC clinical trial and observational study».

Because the present study was designed to be an effectiveness trial and prior studies noted earlier showed that attrition before 12 sessions from child treatment is common in actual clinical settings, parents were given the choice of attending 6 two - hour meetings each of which covered two sessions or the standard 12 one - hour session procedure.

The IHDP began in 1985 and was designed as a eight - site, randomized clinical trial evaluating early childhood development, center - based education, and home - based family support services, as well as pediatric surveillance in an attempt to reduce the risk for developmental delay, behavioral issues and health problems LBW, PT (≤ 37 weeks gestational age) infants.