«Using innovative data normalization and gene selection approaches, we combined the statistical power of multiple genomic studies and masked their variability and batch effects to identify robust
early diagnostic biomarkers of pancreatic cancer,» said first author Manoj Bhasin, PhD, Co-Director of BIDMC's Genomics, Proteomics, Bioinformatics and Systems Biology Center and Assistant Professor of Medicine at HMS.
Not exact matches
Many cancer researchers focus on
biomarkers that could provide
diagnostics for the
early detection of cancer.
The members of the initiative hope to improve
early detection of cancer by making an impact in a variety of areas, including doing epidemiologic studies on risk factors, developing new and improved methods of
diagnostic imaging, discovering and verifying new
biomarkers as indicators of cancer, and developing new technologies to aid
early detection.
And we are now taking advantage of the different skills that we have in the consortium to try to interpret these and see how they evaluate the potential to be a
biomarker of either progression or an
early diagnostic tool.