Sentences with phrase «early differentiation»

«Developmentally, stem - cell derived neurons are close to a fetal state, recapitulating early differentiation of cells,» says Maria Sundberg, PhD, the paper's first author.
However, genome integrating viral vectors and oncogenic transcription factors are still key parts of many reprogramming schemes, and many early differentiation studies need to be confirmed using iPSCs generated using safer non-integrating viral vectors.
To confirm that early differentiation pattern exhibited in the V+S + fraction was indeed an early state in PrEn differentiation, rather than a metastable pro-differentiation state similar to that described for the Oct4 positive populations that do not express Nanog, Rex1, or Stella [8]--[11], we examined the behaviour of gene sets representing other lineages in our data set (Figure 3C and Figure S3).
Hierarchical clustering organized samples according to differentiation stages, with undifferentiated ES cells and early differentiation states at the left and progressively more differentiated states toward the right.
Follicle cells undergo a binary choice during early differentiation.
In the case of planarians, the gene egr - 4 seems to perform an early control of cell proliferation as a response to amputation, and be involved later in the early differentiation of brain during regeneration.
«The genetic regulation of these early differentiation processes has been extensively investigated in the mouse.
Researchers led by Professor Eckhard Wolf, Chair of Molecular Animal Breeding and Biotechnology at the Gene Center and the Department of Veterinary Sciences at LMU, now report in the journal PNAS, that early phases of the development of bovine embryos, might offer a better system for the understanding of the earliest differentiation steps.
Further, we demonstrate that deletion of Alkbh1 in embryonic stem cells leads to upregulation of the core genes involved in pluripotency and that ALKBH1 is required during early differentiation.
He has developed and applied a range of isotope geochemical and cosmochemical tools to shape our understanding of the origin of continental magmas, the formation of the continental crust and lithospheric mantle, the early differentiation of the Earth and Moon, and the chronology of the early Solar System.
The early differentiation of Mars inferred from Hf — W chronometry.
A new agreement should recognize that a simple one - formula - fits - all framework is not feasible: We don't know how to allocate emissions among nations, the global economy makes this impossible anyway, and the early differentiation between developed and developing economies is no longer valid.
The results provide evidence for the continuity of early behavioral and emotional problems and support for the early differentiation between internalizing and externalizing problems.
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