An emerging strategy
in early drug discovery entails using fragments, i.e. molecules smaller than conventional drug candidates, as starting points for design of novel therapeutic compounds.
«The scientists stand accused of emailing and downloading proprietary data about [GlaxoSmithKline] products and sending it to contacts working for the Chinese startup Renopharma, which provides contract research services
for early drug discovery, according to its website.»
Alzheimer's Research UK is currently funded several
promising early drug discovery programmes focused on inflammation in Alzheimer's and it is an important area of ongoing research.
The Drug Discovery & Development platform (DDD platform) will focus
on early drug discovery and take promising candidates as far as demonstrating in vivo efficacy in relevant models.
Despite ongoing efforts toward finding novel entities for the treatment of the most challenging cancers, translation into patient benefit has been slow due to the fact that translational cancer research
from early drug discovery to late stage drug development and assessment in clinical trials is a long process.
The scientists stand accused of emailing and downloading proprietary data about GSK products and sending it to contacts working for the Chinese startup Renopharma, which provides contract research services
for early drug discovery, according to its website.
In a paper published in Nature Biotechnology, researchers from the Broad Institute of MIT and Harvard and the Dana - Farber Cancer Institute describe a new method that dramatically simplifies an arduous experimental process
in early drug discovery.
If drug makers incorporated this technique into
their early drug discovery process, he said, it would help identify which version of an atropisomeric compound actually targets the kinase they want to target, cutting the potential for side effects and helping to usher drugs past strict regulatory hurdles and into the hands of waiting patients.
Willson has been a long time supporter of precompetitive chemistry in
early drug discovery and was a scientific founder of the SGC Epigenetic Chemical Probes project.
Willson has been a long - time supporter of precompetitive chemistry as a mechanism to bring innovation to
early drug discovery.