Accordingly, they emerge quite
early during embryonic development.
Additionally, the hippocampal chandelier cells were born several days
earlier during embryonic development than the neocortical ones.
Not exact matches
«This burst of genetic changes happens only
during the
early stages of
embryonic development and then it stops,» Liu said.
Facial asymmetries and minor physical anomalies begin to appear
early in
embryonic development, mainly the first trimester of pregnancy, and can be a sign of instability
during this growth.
When Kaufman, Zon and colleagues looked to see what was different about these
early cancer cells, they found that crestin and the other activated genes are the same ones turned on
during zebrafish
embryonic development — specifically, in the stem cells that give rise to the pigment cells known as melanocytes, within a structure called the neural crest.
This technology was pioneered by Shinya Yamanaka, who showed that the introduction of four specific proteins that are essential
during early embryonic development could be used to convert adult cells into pluripotent cells.
This discovery by the scientists at the CRG provides an insight into stem cell - forming molecular mechanisms, and is therefore of great interest for studies on the
early stages of life,
during embryonic development.
The researchers speculate that some cases of schizophrenia afflicting only one of a pair of identical twins could be due to mutations causing the expansion of trinucleotide repeats in the affected twin
during the
early embryonic development.
The ability of a fertilized egg to generate both
embryonic and extra-
embryonic tissues is referred to as «totipotency,» an ultimate stem cell state seen only
during the
earliest stages of
embryonic development.
But the researchers also put a copy of the Myd88 gene near a special «promoter» sequence of DNA that gets switched on
during early embryonic development.
During early embryonic development, cells throughout the forming retina are proliferative.
During early embryonic development, XpdTTD is dominant over the Xpd † XPCS and Xpd † XP alleles, whereas later in the ontogenesis of skin, hair - shaft, and blood cells, the situation is reversed.
They are present
during the
early stages of
embryonic development and possess the ability to become, or «differentiate,» into almost any tissue within the body.
Newly evolved genes can rapidly assume control over fundamental functions
during early embryonic development, report scientists from the University of Chicago.
The sequential appearance of genes specific to
early developmental stages matches the timing of their induction
during embryonic development.
Moreover, ES cell differentiation in vitro recapitulates events that take place
during early embryonic development including the formation of the three germ layers of ectoderm, mesoderm and endoderm, and the emergence of endothelial, hematopoietic, cardiac, neuronal and hepatic or pancreatic cells [8], [9].
For example, clusters containing genes that are upregulated
during the course of ES cell differentiation (Table 3) include in order of time of expression: cluster 30 that represents genes which take part in the formation of the three
embryonic germ layers
during gastrulation, i.e., Goosecoid, Cerberus like 1 homolog, Wnt3, Mesp1, Mixl1, mEomes and Even - skipped 1; cluster 15 containing molecular regulators of
early mesoderm
development including Bmp2, Bmp5, Msx1, Msx2, Cripto, Tbx20, Hey2, Smad6, Vegfr2 (Kdr), Foxf1 and Hand1; cluster 20, which comprises regulatory and structural genes linked to hemopoiesis such as Gata1, Nfe2, Klf1, Tie1, hemoglobins (Hba - x, Hbb - b1) and Glycophorin A; cluster 12, which is rich in genes involved in cardiac
development, e.g., Mef2c, Myl4, cardiac Troponin T2, Tropomodulin 1, myosin binding protein C, Bves, Angiopoietin 1 and Angiopoietin 2; and, cluster 4, which consists mostly of genes associated with neuronal
development and differentiation, for example, Neurog1, Neurog2, Olig2, Nkx6.1, Neurod4, Pou3f2, Pou3f4, Cacna2d3, Cacng4, Kcnq2 and EphA5.
It has also been reported that Kap1 controls endogenous retroelements
during early embryonic development and in
embryonic stem cells but not in adult fibroblasts [45].
May 07, 2015 Genetic changes to basic developmental processes evolve more frequently than thought Newly evolved genes can rapidly assume control over fundamental functions
during early embryonic development, report scientists from the University of Chicago.