Sentences with phrase «early effects of the disease»

Not exact matches

Furthermore, an early - stage study pumping up the dose of its hemophilia A treatment — which aims to be a one - time therapy for the rare blood clotting - related disease — appeared to hit its targets without serious side effects.

In this first article, a summary is given of how and where the banana export trades began, the early history of Panama disease, and the important effect that the disease had on the development of this industry.

The neuroprotective effects of nicotine were studied in a randomized clinical trial involving 67 subjects in the early stages of Alzheimer's disease, where memory was slightly impaired but decision - making and other cognitive abilities remained intact.

As a result, the emphasis in early development is on understanding the molecular underpinnings of disease and developing markers for therapeutic effects.

Early results show that it causes a drop in levels of certain white blood cells, increasing the possibility of infections, and raises cholesterol, a worrying side effect in a patient population that is already prone to cardiovascular disease.

Should doctors treat patients in early stages of Parkinson's disease, when drug side effects may be worse than the symptoms they alleviate?

«Specifically, we are looking at the effects of these early factors on later levels of C - reactive protein (CRP), a biomarker associated with risk for cardiovascular and metabolic disease,» Metzger said.

According to Dr. Rosamilia, early treatment not only can reduce the pain and severity of the disease, but also can help prevent potential side effects like eye problems, infection, and a condition called post-herpetic neuralgia, which causes pain, numbness, itching and tingling.

An initial clinical trial of simvastatin in people with early - stage MS showed reductions in brain lesions, suggesting an effect on the underlying disease process.

Based on these findings, DTI may offer a role in assessing brain damage in early Alzheimer's disease and monitoring the effect of new therapies.

Albertini replied that there might be subtle health effects, such as early onset of adult diseases like diabetes and cancer, that won't appear until 15 or 20 years after IVF, and he pointed out that there is very little follow - up data on the health of children created through assisted reproductive medicine.

Appel and Sacks led three earlier clinical trials that tested ways to reduce the risk of cardiovascular disease and diabetes, providing volunteers with carefully designed diets and measuring the effects on key health indicators.

«The combination of two proteins exerts a regenerating effect in Parkinson's disease: Synergy between two neurotrophic factors may be beneficial particularly during an early phase of the disease.»

The evidence of the success of early rice farmers on the vast wetlands near the Guaporé River in Rondônia state, Brazil, could help modern day plant breeders develop rice crops which are less susceptible to disease and more adaptable to the effects of climate change than the Asian varieties.

One key to counteracting the devastating effects experienced by patients is detecting the disease early, and another feat by Holtzman, with Randall J. Bateman, also at the Washington University School of Medicine, should make that possible.

It is worthwhile to give patients expensive new drugs that can cure their hepatitis C much earlier than some insurers are now willing to pay for them, according to a UC San Francisco study that models the effects of treating the disease early versus late in its development.

Earlier work by Skinner has found epigenetic effects from a host of environmental toxicants, connecting plastics, pesticides, fungicide, dioxin and hydrocarbons to diseases and abnormalities as many as three generations later.

These findings demonstrate that the vascular effects of sleep apnea are reversible if treated early in the disease process, suggesting that we might be able to mitigate the long - term risk of chronic exposure to OSA.»

In their «Editorial comment to the «NIA - AA Research Framework: Towards a Biological Definition of Alzheimer's Disease,»» Nina Silverberg, Ph.D., Cerise Elliott, Ph.D., Laurie Ryan, Ph.D., Eliezer Masliah, M.D., and Richard Hodes, M.D., of NIA point out that the Framework — in addition to improving early detection and the development of new therapies — could potentially «allow more precise estimates of how many people are at risk [for or living with] Alzheimer's disease, how best to monitor response to therapies, and how to distinguish the effects of Alzheimer's disease from other similar pathologies.Disease,»» Nina Silverberg, Ph.D., Cerise Elliott, Ph.D., Laurie Ryan, Ph.D., Eliezer Masliah, M.D., and Richard Hodes, M.D., of NIA point out that the Framework — in addition to improving early detection and the development of new therapies — could potentially «allow more precise estimates of how many people are at risk [for or living with] Alzheimer's disease, how best to monitor response to therapies, and how to distinguish the effects of Alzheimer's disease from other similar pathologies.disease, how best to monitor response to therapies, and how to distinguish the effects of Alzheimer's disease from other similar pathologies.disease from other similar pathologies.»

In particular, a transgenic mouse model of early Alzheimer's disease shows that the more focally targeted an intervention is, the more specific of an effect can be elicited.

It is difficult to know whether any earlier intervention may have altered her current condition as we are only just learning about the potential long term effects of Ebola virus disease and management of complications / secondary effects.

A Competitor Mounts the Starting Blocks It would be exciting enough for one AS - targeting rejuvenation biotechnology (or one and a half, if PD03A is counted separately) were making such progress through the clinical pipeline, especially in light of the early hints of a disease - modifying effect.

She joined the lab in 2014 and is interested in understanding the molecular mechanisms underlying early synaptotoxic effects of Amyloid - β in context to Alzheimer's disease.

It focuses on the mechanisms underlying the expression and the inheritance of the effects of environmental conditions such as traumatic stress in early postnatal life, on behavior and physiology, and their link with diseases in humans.

Since the early discovery of caffeine's stimulant effect, studies have since linked the drug to reduced risk of heart disease, type 2 diabetes, and cancer.

Conventional medicine, as you called it earlier, was created in response to mainly acute disease where you have a single cause and single effect, and now medicine is trying to adapt to this now environment of chronic disease, which is driven by lifestyle, it's multi-systemic, it's across many different organs, and so that linear model of thinking doesn't really work.

1935 Effects of the high carbohydrate - low calorie diet upon carbohydrate tolerance in diabetes mellitus 1955 Low - fat diet and therapeutic doses of insulin in diabetes mellitus 1958 Effect of rice diet on diabetes mellitus associated with vascular disease 1976 Beneficial effects of a high carbohydrate, high fiber diet on hyperglycemic diabetic men 1977 Effect of carbohydrate restriction and high carbohydrates diets on men with chemical diabetes 1979 High - carbohydrate, high - fiber diets for insulin - treated men with diabetes mellitus 1981 High carbohydrate high in fibre diet in diabetes 1982 Response of non-insulin-dependent diabetic patients to an intensive program of diet and exercise 1983 Long - term use of a high - complex - carbohydrate, high - fiber, low - fat diet and exercise in the treatment of NIDDM patients 1994 Diet and exercise in the treatment of NIDDM: the need for early emphasis 1999 Toward improved management of NIDDM: A randomized, controlled, pilot intervention using a lowfat, vegetarian diet 2005 The effects of a low - fat, plant - based dietary intervention on body weight, metabolism, and insulin sensitivity 2006 A low - fat vegan diet improves glycemic control and cardiovascular risk factors in a randomized clinical trial in individuals with type 2 diabetes 2006 Effect of short ‐ term Pritikin diet therapy on the metabolic syndrome 2009 A low - fat vegan diet and a conventional diabetes diet in the treatment of type 2 diabetes: a randomized, controlled, 74 - wk clinical trial

Fat — A series of studies that were published in the early 80's that claimed fat consumption would lead to obesity, heart disease, and a slew of other ill effects.

«The positive ecological correlations between national intakes of total fat and saturated fatty acids and cardiovascular mortality found in earlier studies were absent or negative in the larger, more recent studies,» the authors wrote, concluding that «the harmful effect of dietary saturated fatty acids and the protective effect of dietary polyunsaturated fatty acids on atherosclerosis and cardiovascular disease are questioned.»

«We focused on children because early exposure can have long - term effects on disease outcomes,» says Rainbow Vogt, lead author of the study.

Some of the early work by Hierholzer and Kabara (1982) that showed virucidal effects of monolaurin on enveloped RNA and DNA viruses was done in conjunction with the Center for Disease Control of the U.S. Public Health Service.

Smoking's unhealthy effect may «overwhelm the influence of coffee intake on early cardiovascular disease,» Miranda reasoned.

This compelling knowledge base underscores three significant, unmet needs: (1) valid and reliable biological and bio-behavioral measures (or «biomarkers») of «toxic stress» to identify children who are at higher risk of chronic disease in adulthood; (2) more effective intervention strategies to prevent, reduce, or mitigate the long - term health consequences of significant adversity in early childhood; and (3) biomarkers that are sensitive to change and can thus be used to assess the short - term and medium - term effects of intervention strategies whose ultimate impacts on physical and mental health may not be apparent until decades later.

The increased incidence of joint diseases among early - neutered dogs seen in some studies may be due to the effect of neutering on young dogs» growth plates, and therefore the timing of neutering, based on dog breed, may be able to offset these issues.

At one end of the severity spectrum, early chronic valvular disease, some forms of hypertrophic cardiomyopathy and some mild congenital heart defects may have little effect on an animal's lifestyle or life expectancy; at the other end, severe heart failure can interfere with even simple activities and prove rapidly fatal.

The study was designed to examine the effects of neutering on the risks of several diseases in the same breed, distinguishing between males and females and between early or late neutering and not neutering.

The study was designed to examine the effects of neutering on the risks of several diseases in the same breed, distinguishing between males and females and between early or late neutering and non-neutering.

For example, the increased incidence of joint diseases among early - neutered dogs is likely a combination of the effect of neutering on the young dog's growth plates as well as the increase in weight on the joints that is commonly seen in neutered dogs.

The earlier in the course of disease that acupuncture is started and the more numerous and frequent the treatments, the better the response tends to be, and the longer a dis - ease has been present, the longer it will take to see a positive effect.

So this page covers some of the early symptoms and signs of cat diseases, infections and anything that effects the health and well being of your cat.

The intent of the study was to investigate the effects of neutering on the risks of several diseases in a single breed of dog, distinguishing between males and females, and between dogs that had been neutered or spayed early (before one year), late (after one year), or not at all.

Given the widespread practice of neutering in the U.S., especially with public campaigns promoting early neutering, and the contrast with neutering practices in other developed countries, the objective of this project was to retrospectively examine the effects of neutering on the risks of several diseases in the same breed, distinguishing between males and females and early or late neutering versus remaining intact using a single hospital database.

It is often overlooked that there are physical causes of these changes, and when recognized early, the deteriorative effects of disease can be significantly delayed.

This harmful disease of the mouth effects up to 80 % of pets by age 3 and can occur as early as 6 months of age!

We wrote about a prime example of such a case of self - censorship earlier this year, when the Centers for Disease Control abruptly canceled a large conference on the human health effects of climate change.

«The sum of the evidence against saturated fat over the past half - century amounts to this: the early trials condemning saturated fat were unsound; the epidemiological data showed no negative association; saturated fat's effect on LDL - cholesterol (when properly measured in subfractions) is neutral; and a significant body of clinical trials over the past decade has demonstrated the absence of any negative effect of saturated fat on heart disease, obesity, or diabetes.

Rooted in a deepening understanding of how brain architecture is shaped by the interactive effects of both genetic predisposition and environmental influence, and how its developing circuitry affects a lifetime of learning, behavior, and health, advances in the biological sciences underscore the foundational importance of the early years and support an EBD framework for understanding the evolution of human health and disease across the life span.

Pediatricians are now armed with new information about the adverse effects of toxic stress on brain development, as well as a deeper understanding of the early life origins of many adult diseases.

It found a significant «dosage» effect between the number of such experiences reported and increased risk, in adulthood, for cardiovascular, lung, and liver disease; depression; smoking; drug and alcohol abuse; obesity; risky sexual behaviors; and early mortality.

Early detection of depression, anxiety, eating disorders, and learning disabilities can facilitate effective treatment options and help minimize adverse effects on diabetes management and disease outcomes (13).