In essence, these studies suggested that a newly fertilized, enucleated egg has the ability to «reprogram» a much older donor nucleus, making the resultant cell behave as though it were at a very
early embryonic state.
In comparison with the cells obtained with the technique developed by Yamanaka, the stem cells obtained by CNIO therefore represent an even
earlier embryonic state, with greater capacity for differentiation.
Not exact matches
By analysing the
early steps that precede tumor formation, Alexandra Van Keymeulen and colleagues found that expression of oncogenic Pik3ca reactivates a multilineage differentiation program in adult stem cells that resembles to an immature
embryonic state.
The ability of a fertilized egg to generate both
embryonic and extra-
embryonic tissues is referred to as «totipotency,» an ultimate stem cell
state seen only during the
earliest stages of
embryonic development.
The third and most recent round of grants awarded
earlier this year for stem cell research by the
state of Minnesota tracks a pattern established with the two
earlier rounds of grants: a noticeable lack of support for human
embryonic stem cell research.