Of the 29
early embryos created by somatic - cell nuclear transfer and implanted into various ewes by Roslin researchers, only one, Dolly, survived, suggesting that the technique currently has a high rate of embryonic and fetal loss.
Not exact matches
Research on a new «gene editing» technology known as CRISPR — which theoretically allows any cell or organism to have its genome altered — is advancing exponentially, with
early research ongoing on human
embryos created for that purpose.
When researchers
create «chimeric» mice by injecting iPS cells into
early - stage mouse
embryos, the resulting animals are unusually prone to cancer.
The paper not only seemed to validate the group's claim a year
earlier that it had
created a single cell line from a cloned human
embryo, but it also reported a huge increase in efficiency for the technique.
Any such
embryos would just be studied during their
early development for now — there are no plans yet to try to
create a pregnancy with them.
A key difference, however, is that Dolly's donor cell came from adult udder cells growing in lab dishes (see ScienceNOW, 24 February), while the donor cells used to
create the monkey clones came from
early embryos.
For now, the new stem cell lines UC Berkeley researchers have
created will help scientists understand the first molecular decisions made in the
early embryo.
Some researchers are pleased with the report, saying it is consistent with previous conclusions that safely altering the DNA of human eggs, sperm, or
early embryos — known as germline editing — to
create a baby could be possible eventually.
A team of scientists from the New York Stem Cell Foundation Laboratory
created 13
early - stage human
embryos that were partial genetic clones of diabetic patients.
The same technique — injecting pluripotent stem cells into
early embryos — failed with other combinations: The scientists couldn't
create rat - pig chimeras, and although they produced human - cow chimeric
embryos, they did not transfer them into cows to develop into fetuses.
Summary: Extremely powerful genes that govern the shape of an
embryo from the
earliest stages of development have been tinkered with by nature over the course of evolution to
create the enormously wide range of animal forms, scientists report in the August 14, 1997 issue of Nature.
Extremely powerful genes that govern the shape of an
embryo from the
earliest stages of development have been tinkered with by nature over the course of evolution to
create the enormously wide range of animal forms, scientists report in the August 14, 1997 issue of Nature.
In answer to the question of whether hybrid
embryos created by CNR might be likely to develop if placed into a woman, the Royal Society notes that it is impossible to answer this question without carrying out an illegal experiment, but that experience to date with other inter-specific hybrid
embryos suggests that development beyond the very
earliest stages of gestation would be unlikely.
August 14, 1997 Evolution re-sculpted animal limbs by genetic switches once thought too drastic for survival Extremely powerful genes that govern the shape of an
embryo from the
earliest stages of development have been tinkered with by nature over the course of evolution to
create the enormously wide range of animal forms, scientists report in the August 14, 1997 issue of Nature.