Reduction of CD4 - SP cells in the thymus can be observed even in the neonate, suggesting that the defect is a relatively
early event in positive selection (Fig. 2D).
For his research project to explore a novel idea in the field of neurodegeneration, defining the molecular cascade that controls axon degeneration, which is a key
early event in glaucoma, Dr. Richard Libby was awarded the 2017 Shaffer Prize from Glaucoma Research Foundation.
Microglial activation is
an early event in PD that spreads to all disease - affected regions of the brain.
In the process they induce inflammation; the cells also secrete other inflammatory chemicals, like interleukin - 6 and tumor necrosis factor - alpha, which are known to adhere to the endothelium of the blood vessels,
an early event in atherosclerosis.
A press release elaborated on its plot: «The comic depicts
early events in Colonel Sanders» life that eventually led to the discovery of his real super power: the combination of a pressure cooker and secret blend of 11 herbs and spices, better known as his world - famous Original Recipe Chicken.»
which predict
the early events in Jesus» life (1:20 - 3; 2:13, 19 - 22), the dream of the Magi (2:12), and the dream of Pilate's wife (27:19), which showed Pilate that Jesus was a «righteous man» (27:24).
Rep. Carolyn Maloney appeared with Hochul at a rally last week, and Rep. Grace Meng appeared at
an earlier event in Queens with the lieutenant governor candidate.
«It's long been my hunch that
the earliest events in left - right asymmetry involve a shunting [of signaling proteins such as ZIC3] to one side or the other, and it's certainly appealing to invoke dyneins and the cytoskeleton to help with that,» says Casey.
These results have important implications for HIV vaccine development and for understanding
the earliest events in HIV transmission.
Researchers used a specific type of titration method that revealed the details about very
early events in the spicule formation.
And when I started off in this field, about 20 years ago, I was pretty confident that it would be something we could do relatively [easily],
these early events in [an] RNA catalyzed replication system, and that's turned out to be substantially more difficult than I thought.
One of
the earliest events in Alzheimer's is disruption of the brain's synapses (the small gaps across which nerve impulses are passed), which can lead to neuronal death.
Ultimately, this knowledge will be useful for understanding the very
early events in human development, which are reflected in the naïve and primed stem cell states, and could also lead to improved methods to reprogram human cells for stem cell - based therapies.
Early events in foamy virus - host interaction and intracellular trafficking.
When Simon's team deleted all H3.3 genes, they found that certain previously silenced transposable elements were reactivated and continued to multiply in the genome — the result is the appearance of new genetic alleles and chromosomal abnormalities, both are familiar
early events in the formation of tumors.
Currently, he is at The Rockefeller University where, as a Junior Fellow of the Simons Society, he uses stem cells to build experimental models of the human embryo, aimed at elucidating
the earliest events in human development.
Dongxian made key advances in the study of motor neuron degeneration, including the discovery of novel neuroprotective factors and biomarkers of
early events in disease pathology.
Identifying
the earliest events in neurodegeneration in glaucoma is important because if you can stop those early events then hopefully you can stop progression or slow progression and give the central nervous system time to recover from the initial insult.
This suggests that reduced glucose utilization in the brain might be one of
the earliest events in AD.
Moreover, models of experimental carcinogenesis in animals have shown the potential to modify a number of metabolic actions and steps in the cell cycle in a way that
early events in the cascade of cancer development may be counteracted while stages of progression may be slowed down.
One of
the earliest events in the development of atherosclerosis is the recruitment of inflammatory white blood cells from the blood to the arterial wall by vascular cell adhesion molecules (42).
From the events of the evening, at least as perceived by Jean, we flashback to
earlier events in their relationship, from meeting to proposal, followed by the aftermath of Jean hanging on while Herman takes a new lover in his secretary, Lynne (Sevigny, Broken Flowers).
The editing and structure found within Dunkirk is something so fresh as to be considered groundbreaking and keeps the intensity of one of
the earliest events in the war at an all - time high.
The post-credits scene is a nice nod to
earlier events in the Marvel Cinematic Universe.
The Gothams are one of
the earliest events in the annual film - awards derby, and are considered by many to be the kickoff the season.
Not exact matches
At an
event in Nashville
in early February for retail - store employees, Legere made a surprise appearance.
This two - day activity - filled
event includes a Day 1 hands - on workshop to continue the company's efforts
in building and expanding end - user base among medical and dental healthcare providers, but also provide organizations with how - tos to become
early adopter and users of 3D printing and bio-printing technologies.
Attendance at the
event costs $ 10,000 for a standard ticket (first - time,
early - career attendees can get a discount), which means the
in - person TED experience is filled with notable leaders
in science and technology.
A similar case to EuropaCorp's «Kursk,» the true story of a Russian submarine that sank
in the Barents Sea
in 2000 and killed everyone on board; though Putin had a significant role
in the
events, appears
in the source material of Robert Moore's best - seller «A Time to Die,» and even featured
in early versions of the screenplay, he's nowhere to be found
in the finished film.
A math whiz from an
early age,
in high school he interned at O'Reilly Media, a publisher of technical books which also produces geeky
events like Foo Camp and Strata.
And she uses flexible scheduling: If employees need to leave
early for an
event, they can come
in a few hours
early to make up the time.
At a Veterans» Day
event this morning, Republican Senate candidate Roy Moore again denied claims that he had been sexually involved with a 14 - year - old girl when he was
in his
early thirties, and reiterated that he will not step down from his Alabama race against Democrat Doug Jones.
The tech company is planning to hold a press
event in early April, when the company will unveil a 10.5 - inch iPad, manufacturing industry news site Digitimes is reporting, citing sources within Apple's supply chain.
Jenkins says he's working with universities
in the D.C. area to formalize and host the next
event sometime
in early 2016.
«There are at least 50 active funds
in Turkey looking at investments,» says A. Mete Cakmakci, a member of the Istanbul Venture Capital Initiative, a Turkish investment fund, at a panel discussion at the Dell women's
event earlier this month.
While Black Friday is a diluted
event, with sales starting
earlier in the month at most major chains, it still anchors the biggest shopping weekend of the year and can get a retailer's holiday season off to a good, or bad, start.
In a historic turn
events that has left investors around the world reeling, Britain voted to leave the European Union
early Friday morning.
«Look to your right; look to your left,» Tisch said at a recruiting
event in early January, modifying the Harvard Law School warning to first - year students.
IT might not feel like it, but there are
early signs of boom conditions forming
in some parts of the state's mining industry, with two sectors
in particular benefiting from
events in the markets for commodities, labour, and capital equipment.
Some analysts have questioned whether Kim, believed to be
in his
early 30s, would choose for his first overseas visit an
event where he would share the stage with several leaders and have less control over proceedings than
in a two - way summit.
Earlier this year, a company called
Event Shares filed a prospectus for a Republican Policies and a Democratic Policies fund to invest
in companies that will benefit from the respective parties» political agendas (neither has launched yet).
Shkreli didn't resign from his post as Turing CEO until December 18, the day after his arrest on charges of securities fraud related to
events earlier in his career.
The new Nike + app, which executives previewed
earlier this year at a media
event held
in New York City, will give users a mix of services (booking one - on - one retail appointments), training and running advice tips, shopping tips, and a form of social commerce that has become increasingly popular
in the athletics category.
A large portion of the spread compression happened
in reaction to two
events: the Fed's decision to begin winding down its large - scale asset - purchase program known as quantitative easing on Dec. 18, and Janet Yellen's first meeting as Fed chair on March 19, which coincided with the release of forecasts by Fed officials who anticipated
earlier rate hikes than before.
The
event is scheduled for Nov. 11 — Veterans Day — and will focus on celebrating active military as well as the contributions of veterans throughout U.S. history, the Pentagon said
in a memo
earlier this month.
Experts said it was too
early to tell how
events in Rotterdam might affect the election, though the two front runners have both campaigned on tough - on - immigration themes.
«If a lucky
event early in a CEO's tenure is not balanced by an unlucky one is such a short time period, then that CEO could be wrongfully credited for high performance that would have happened no matter who was leading the company,» according to the study.
United said this week its chief executive met with the Chinese consulate
in Chicago over the possible impact to bookings from a customer being dragged off a plane but it was too
early to tell if business
in China had been hit by the
event.
John Coffee, a law professor at Columbia University and an expert
in securities law, says he believes the company should have disclosed news of the death
earlier, and the fact that the stock didn't fall following the news of the crash doesn't prove the
event wasn't material and shouldn't have been disclosed.
Not surprisingly, Trump joked
earlier in the week that the Democratic debate would fall flat with television audiences while he promised to live - tweet what he predicted would be a «boring»
event.