Not exact matches
Readers will have at their fingertips key articles in the history of science from the late 19th through the
early 21st centuries, including research about the
human genome,
breast and colon
cancer genes, and the Bose - Einstein condensate in physics.
In
earlier studies involving animal models and
human cancer cell lines, researchers found that
breast cancer spreads when three specific cells are in direct contact: an endothelial cell (a type of cell that lines the blood vessels), a perivascular macrophage (a type of immune cell found near blood vessels), and a tumor cell that produces high levels of Mena, a protein that enhances a
cancer cell's ability to spread.
Lead author Moustafa Abdalla writes: «Almost all genomic studies of
breast cancer have focused on well - established tumours because it is technically challenging to study the
earliest mutational events occurring in
human breast epithelial cells.»
PALLAS: Palbociclib Collaborative Adjuvant Study: A Randomized Phase III Trial of Palbociclib with Standard Adjuvant Endocrine Therapy versus Standard Adjuvant Endocrine Therapy Alone for Hormone Receptor Positive (HR +) /
Human Epidermal Growth Factor Receptor 2 (HER2)- Negative
Early Breast Cancer
Aug 8, 2008 Two New Predisposition Genes For
Breast, Thyroid And Kidney
Cancers Could Lead to More Accurate Diagnosis and
Earlier Detection of These
Cancers Charis Eng, MD, PhD, Sondra J and Stephen R Hardis Endowed Chair of
Cancer Genomic Medicine and Chair, GMI, and her team published in the Aug 8, 2008 issue of the American Journal of
Human Genetics that germline mutations in SDHB and SDHD, which play key roles in the mitochondria (the cell's power houses), predispose to Cowden and Cowden - like syndromes.
pSTAT5 is detected in
human breast early lesions, especially in women who have had a pregnancy; therefore, prophylactic therapy targeting Jak2 - STAT5 signaling may lower
breast cancer risk in high risk women.
Antioxidants and other active components of prickly pear induced
early cell death in
human breast and colon
cancer cells, with a more pronounced effect occurring in colon
cancer cells.
According to the FDA, 17 % of the American diet comes out of cans, and many of those have an epoxy liner made with Bisphenol A, a chemical which can mimic
human estrogen and which is linked to
breast cancer and
early puberty in women.