Sentences with phrase «early lesions from»

Since pSTAT5 + cells occur at 10-fold higher frequency than pSTAT3 + cells in early lesions from our mouse model (18 % vs 1.8 %), C188 - 9 is effectively a STAT5 inhibitor in this setting.

Apoptosis levels were inversely correlated with levels of pSTAT5 in early lesions from these two groups of mice (Figure 4 — figure supplement 2B).

Not exact matches

«The identification and initial validation of a highly accurate 5 - gene pancreatic cancer biomarker panel that can discriminate late and early stages of pancreatic cancer from normal pancreas and benign pancreatic lesions could facilitate early diagnosis of pancreatic cancer,» said co-senior author Roya Khosravi - Far, PhD, Associate Professor of Pathology at BIDMC.

But precursor lesions that form in the pancreas and its ducts can signal the disease before it strikes, and when caught early enough, they can be prevented from progressing to become cancer.

«Hypoxia can occur for many reasons, but in early FOP flare - ups, we speculated that hypoxia might result from the inflammatory microenvironment in lesions,» Kaplan said.

Results of a phase one trial show that an investigational topical drug, resiquimod gel, causes regression of both treated and untreated tumor lesions and may completely remove cancerous cells from both sites in patients with early stage cutaneous T cell lymphoma (CTCL)-- a rare type of non-Hodgkin lymphoma that affects the skin.

CFSs now appear as preferential targets for oncogene - induced replication stress in precancerous lesions, which suggests that their instability promotes oncogenesis from early stages of the process.

Diagnosis of early Lyme disease by polymerase chain reaction amplification and culture of skin biopsies from erythema migrans lesions

It can pick up early lung cancers and can reduce mortality from lung cancer by about 20 %, but a large number of the early lesions that are seen probably never would go on to being lethal cancer and being able to discriminate between those that will cause trouble and those that won't make a huge difference in cancer therapy.

Harold Varmus: Well the simplistic way to think about that is and I'm not sure this is the way it will be worked out, is to be able to take just a few cells from those early lesions and examine them genetically or for other kinds of marks on the DNA that would predict whether or not this is some - this is a lesion which might or an early stage growth that might never be able to progress, but it is also possible that every early tumor of that kind has some probability of expanding and invading and growing to become a medical problem, so getting that right will obviously be crucial because it's very difficult to say when you've diagnosed something that is an early stage tumor that it won't progress.

«Many cats with severe hypertensive ocular damage present with blindness and bilateral mydriasis resulting from complete retinal detachments and / or intraocular haemorrhage; the changes are often irreversible... Lesions that are not associated with an impaired menace response or pupillary light deficits... are much more amenable to anti-hypertensive treatment... highlighting the importance of early diagnosis and management.

According to information provided by the dog owners, at least some of the Swedish vallhund dogs with MAC - like lesions suffered from severe gastrointestinal parasitism early in life which may have resulted in multifocal chorioretinitis.