Sentences with phrase «early life exposures on»

The effect of intrauterine / early life exposures on adult onset cancers is an area of growing interest of Program members (Farzan, 2013).

Not exact matches

For the financial markets, those risks are compounded by the unbalanced «risk - on» exposure that investment managers and institutions adopted early this year, encouraged by a short - lived burst of economic activity, and faith in a central - bank backstop.

«Chronic exposure to pesticides during the early life stage of honeybees may contribute to their inadequate nutrition or direct poisoning with a resulting impact on the survival and development of the entire bee brood,» he said.

Pandey explained that early life exposure to alcohol can have not only long - lasting effects on brain chemistry but also induce a predisposition to psychiatric problems such as alcohol abuse and anxiety disorders.

«Early life exposure to lead causes a long lasting impact on gut microbiome, and the change of gut microbiome may partially contribute to the increased body weight in adult life,» said lead author Chuanwu Xi, associate professor of environmental health science.

I have concerns about early - life exposures, and how that may predispose for breast cancer later on.

Last summer, a panel of 38 researchers headed by vom Saal published a report in Reproductive Toxicology warning that BPA (much like the synthetic estrogen diethylstilbestrol, or DES) is a potential chemical time bomb that may lead to multiple problems, including a higher risk of cancer, especially if exposure occurs in the womb or an infant's early life and on an unrelenting daily basis.

The study, published in the New England Journal of Medicine on May 12, found that early lung function predicts lung growth later in life, regardless of asthma treatment and smoking exposure.

The study bolsters the evidence that alcohol exposure early in life can have long - term effects on risk taking and decision making, which can increase a person's risk for substance abuse problems.

Some epidemiologic evidence suggests that arsenic exposure in utero and early in life may be associated with adverse effects on fetal growth, and on infant and child immune and neurodevelopment outcomes.

Microbial Exposure During Early Life Has Persistent Effects on Natural Killer T Cell Function

But it remains unclear whether there are long - term effects from low - intensity or occasional marijuana use earlier in life and whether the magnitude and persistence of impairment depends on the duration of marijuana use or the age of exposure.

One avenue of our translational research aims to determine the impact of in utero HIV - 1 exposure on infant immunity to vaccinations and co-infections by dissecting the infant immune repertoire present at birth in the context of maternal HIV - 1 infection and how the infant T cell repertoire changes following early life exposures compared to infants born to the HIV - 1 uninfected women of similar socio - economic status.

I have experimented on myself, after my early exposure due primarily to dental procedures, living in populated areas with bad air, and a poor diet in my 20's.

With respect to obesity, exposure to EDCs — especially early in life — can lead to obesity later on and obesity genes can be passed along to future generations.

But the authors write in their paper that «emerging epidemiologic evidence suggests that [arsenic] exposure in utero and during early life may be associated with adverse health effects» on immune system and brain development.

The FDA's statement points to research that links exposure to inorganic arsenic early in life to decreased performance on certain developmental tests.

Early features (produced mostly in Australia) included Praise (1998), Dogwatch (1999), and Erskineville Kings (1999), but Edgerton came into his own with his popular ongoing turn as Will McGill on the Aussie soaper The Secret Life of Us, then branched out into increased international exposure with onscreen contributions to two of George Lucas» Star Wars films, Star Wars: Episode II — Attack of the Clones (2002) and Star Wars: Episode III — Revenge of the Sith (2005).

Based on secondary analysis of the Early Childhood Longitudinal Study, children with non or minimal exposure to recess were more likely to be black, low income, live in large cities, to be from the Northeast or South and to attend...

«Based on previous allergy studies conducted here at Henry Ford, exposure to a dog early in life provides protection against dog allergy development.

Pups that don't have this early exposure, become difficult to manage later on in life for simple things like putting on harnesses, clipping nails or even drying off feet.

Dogs that miss out on this early exposure are at high risk to develop problems later in life.

For instance, taking your new dog to the veterinarian early on in life gives him exposure to the veterinary staff and gets him used to a situation that may otherwise be viewed as frightening.

Breast Cancer & The Environment Research Centers: Sixth Annual Early Environmental Exposures Meeting The Breast Cancer and the Environment Research Centers (BCERC) network is conducting epidemiologic and biologic studies investigating the influence of early environmental exposures on pubertal maturation and mammary gland development and the potential of these developmental changes to alter the risk of breast cancer in later Early Environmental Exposures Meeting The Breast Cancer and the Environment Research Centers (BCERC) network is conducting epidemiologic and biologic studies investigating the influence of early environmental exposures on pubertal maturation and mammary gland development and the potential of these developmental changes to alter the risk of breast cancer in laExposures Meeting The Breast Cancer and the Environment Research Centers (BCERC) network is conducting epidemiologic and biologic studies investigating the influence of early environmental exposures on pubertal maturation and mammary gland development and the potential of these developmental changes to alter the risk of breast cancer in later early environmental exposures on pubertal maturation and mammary gland development and the potential of these developmental changes to alter the risk of breast cancer in laexposures on pubertal maturation and mammary gland development and the potential of these developmental changes to alter the risk of breast cancer in later life.

Oppenheim speaks of growing up in Washington and California, his father's Russian ancestry and education in China, his father's career in engineering, his mother's background and education in English, living in Richmond El Cerrito, his mother's love of the arts, his father's feelings toward Russia, standing out in the community, his relationship with his older sister, attending Richmond High School, demographics of El Cerrito, his interest in athletics during high school, fitting in with the minority class in Richmond, prejudice and cultural dynamics of the 1950s, a lack of art education and philosophy classes during high school, Rebel Without a Cause, Richmond Trojans, hotrod clubs, the persona of a good student, playing by the rules of the art world, friendship with Jimmy De Maria and his relationship to Walter DeMaria, early skills as an artist, art and teachers in high school, attending California College of Arts and Crafts, homosexuality in the 1950s and 1960s, working and attending art school, professors at art school, attending Stanford, early sculptural work, depression, quitting school, getting married, and moving to Hawaii, becoming an entrepreneur, attending the University of Hawaii, going back to art school, radical art, painting, drawing, sculpture, the beats and the 1960s, motivations, studio work, theory and exposure to art, self - doubts, education in art history, Oakland Wedge, earth works, context and possession, Ground Systems, Directed Seeding, Cancelled Crop, studio art, documentation, use of science and disciplines in art, conceptual art, theoretical positions, sentiments and useful rage, Robert Smithson and earth works, Gerry Shum, Peter Hutchinson, ocean work and red dye, breaking patterns and attempting growth, body works, drug use and hippies, focusing on theory, turmoil, Max Kozloff's «Pygmalion Reversed,» artist as shaman and Jack Burnham, sync and acceptance of the art world, machine works, interrogating art and one's self, Vito Acconci, public art, artisans and architects, Fireworks, dysfunction in art, periods of fragmentation, bad art and autobiographical self - exposure, discovery, being judgmental of one's own work, critical dissent, impact of the 1950s and modernism, concern about placement in the art world, Gypsum Gypsies, mutations of objects, reading and writing, form and content, and phases of development.

To understand what makes Herrera's art significant, it helps to consider two major influences on her early artistic life: her friendship with Barnett Newman and her exposure to debates regarding abstraction in postwar Paris.

It is shown that exposure to higher temperatures early in life has negative consequences on adult height.

The findings suggest a significant role of cumulative risk experiences depending on the duration of exposure to poverty, as well as sensitive periods during early life.10, 12 The effect of poverty appears to be slightly stronger on verbal than on non-verbal skills, confirming previous findings.50, 51

Children who experience poverty, particularly during early life or for an extended period, are at risk of a host of adverse health and developmental outcomes through their life course.1 Poverty has a profound effect on specific circumstances, such as birth weight, infant mortality, language development, chronic illness, environmental exposure, nutrition, and injury.

The importance of early interventions that target caregiving is underscored by studies demonstrating high cost - effectiveness through greatly enhanced long - term outcomes.41 Furthermore, children who receive more nurturing caregiving may also be protected from exposure to stressful life events, suggesting this central target may have positive ramifications on brain development.42 Considering these issues, study findings are relevant to the public policy debate on the importance of early preschool programs for young children living in poverty.

Evidence linking psychological stress to asthma continues to grow with our increased understanding of the natural history of asthma and the neurobiology underlying stress vulnerability.1 - 3 Stress exposure during infancy and early childhood may exert particularly robust effects on the physiological systems that respond to stress.4 - 6 Evidence from animal and human studies strongly suggests that early life adversity shapes stress neurobiology, 7 resulting in disturbed regulation of endocrine and autonomic processes (eg, hypothalamic - pituitary - adrenal [HPA] axis, sympathetic - adrenal - medullary system).

Interventions targeting modifiable risk factors (eg, smoking, inactivity, and poor diet) in adult life have only limited efficacy in preventing age - related disease.3, 4 Because of the increasing recognition that preventable risk exposures in early life may contribute to pathophysiological processes leading to age - related disease, 5,6 the science of aging has turned to a life - course perspective.7, 8 Capitalizing on this perspective, this study tested the contribution of adverse psychosocial experiences in childhood to 3 adult conditions that are known to predict age - related diseases: depression, inflammation, and the clustering of metabolic risk markers, hereinafter referred to as age - related - disease risks.

Higher stress exposure and perceived stress during pregnancy have been linked to GDM and / or higher glucose levels in women.43 — 45 Psychological stress and negative life events can be associated with higher salivary cortisol levels during pregnancy, which might relate to higher glucose levels.46 Higher depression scores early in pregnancy also increase the risk for GDM.9 47 On the other hand, social support has been shown to be protective regarding mental health and depression in particular.9 48 49

ECD programmes can take many forms, including promotion of good health and nutrition, support for safe and stimulating environments, protection from risks such as violence or abandonment, parenting support and early learning experiences, media, preschools and community groups.4 Poverty is the key underlying cause of poor child development; children living in poverty are exposed to many negative influences, including poor physical environments, inadequate nutrition, parental stress and insufficient cognitive stimulation.5 Undernutrition can influence brain development directly by affecting brain structure and function, or indirectly via poor physical or motor development, in addition to other pathways.6 — 8 Exposure to multiple co-occurring risks most likely contributes to greater disparities in developmental trajectories among children with differential exposure.9 — 12 This paper focuses on associations between specific aspects of children's physical environments — access to improved water and sanitation (W&S)-- and childhood development as measured by performance on a test of receptive lExposure to multiple co-occurring risks most likely contributes to greater disparities in developmental trajectories among children with differential exposure.9 — 12 This paper focuses on associations between specific aspects of children's physical environments — access to improved water and sanitation (W&S)-- and childhood development as measured by performance on a test of receptive lexposure.9 — 12 This paper focuses on associations between specific aspects of children's physical environments — access to improved water and sanitation (W&S)-- and childhood development as measured by performance on a test of receptive language.

And these environmental effects will vary depending on your child's genes, prenatal factors, and early life exposure to stress.

3 THE EXTENT AND CHARACTER OF HEALTH INEQUALITIES IN THE EARLY YEARS 3.1 Key findings about health inequalities in the first four years 3.2 Introduction 3.3 Pregnancy, birth and the first three months 3.3.1 Risk factors and health outcomes in the early years 3.3.2 Inequalities in the early stages 3.4 Health measures in the first four years of life 3.5 Overview of health outcomes 3.5.1 Physical health 3.5.2 Problems reported by parents 3.5.3 Psychosocial health 3.5.4 Body mass index 3.6 Inequalities in health outcomes 3.6.1 Area deprivation 3.6.2 Household income 3.6.3 Socio - economic classification (NS - SEC) 3.6.4 Conclusion 3.7 Exposure to risk factors likely to have an adverse impact on health 3.8 Inequalities in exposure to risk factors for poor health outcomes 3.8.1 Area deprivation 3.8.2 Houshold income 3.8.3 Socio - economic classification (NS - SEC) 3.8.4 Conclusion 3.9 Summary measure of negative outEARLY YEARS 3.1 Key findings about health inequalities in the first four years 3.2 Introduction 3.3 Pregnancy, birth and the first three months 3.3.1 Risk factors and health outcomes in the early years 3.3.2 Inequalities in the early stages 3.4 Health measures in the first four years of life 3.5 Overview of health outcomes 3.5.1 Physical health 3.5.2 Problems reported by parents 3.5.3 Psychosocial health 3.5.4 Body mass index 3.6 Inequalities in health outcomes 3.6.1 Area deprivation 3.6.2 Household income 3.6.3 Socio - economic classification (NS - SEC) 3.6.4 Conclusion 3.7 Exposure to risk factors likely to have an adverse impact on health 3.8 Inequalities in exposure to risk factors for poor health outcomes 3.8.1 Area deprivation 3.8.2 Houshold income 3.8.3 Socio - economic classification (NS - SEC) 3.8.4 Conclusion 3.9 Summary measure of negative outearly years 3.3.2 Inequalities in the early stages 3.4 Health measures in the first four years of life 3.5 Overview of health outcomes 3.5.1 Physical health 3.5.2 Problems reported by parents 3.5.3 Psychosocial health 3.5.4 Body mass index 3.6 Inequalities in health outcomes 3.6.1 Area deprivation 3.6.2 Household income 3.6.3 Socio - economic classification (NS - SEC) 3.6.4 Conclusion 3.7 Exposure to risk factors likely to have an adverse impact on health 3.8 Inequalities in exposure to risk factors for poor health outcomes 3.8.1 Area deprivation 3.8.2 Houshold income 3.8.3 Socio - economic classification (NS - SEC) 3.8.4 Conclusion 3.9 Summary measure of negative outearly stages 3.4 Health measures in the first four years of life 3.5 Overview of health outcomes 3.5.1 Physical health 3.5.2 Problems reported by parents 3.5.3 Psychosocial health 3.5.4 Body mass index 3.6 Inequalities in health outcomes 3.6.1 Area deprivation 3.6.2 Household income 3.6.3 Socio - economic classification (NS - SEC) 3.6.4 Conclusion 3.7 Exposure to risk factors likely to have an adverse impact on health 3.8 Inequalities in exposure to risk factors for poor health outcomes 3.8.1 Area deprivation 3.8.2 Houshold income 3.8.3 Socio - economic classification (NS - SEC) 3.8.4 Conclusion 3.9 Summary measure of negative Exposure to risk factors likely to have an adverse impact on health 3.8 Inequalities in exposure to risk factors for poor health outcomes 3.8.1 Area deprivation 3.8.2 Houshold income 3.8.3 Socio - economic classification (NS - SEC) 3.8.4 Conclusion 3.9 Summary measure of negative exposure to risk factors for poor health outcomes 3.8.1 Area deprivation 3.8.2 Houshold income 3.8.3 Socio - economic classification (NS - SEC) 3.8.4 Conclusion 3.9 Summary measure of negative outcomes

This review will give an overview of animal and human studies that have focused specifically on the relation between prenatal stress exposure and offspring behaviour or temperament in early life.

Previous studies on telomere length in children focused on severe environmental adversities in early childhood such as living in institutions23 and prenatal tobacco exposure, 24 and demonstrated that the adverse living environment led to telomere shortening in exposed children.

The effects of OXT administration strongly depend on the exposure to stressful experiences in early life.

Past research linking food insecurity to children's outcomes was mostly based on cross-sectional samples [5], [12], [14], [15] or short follow - up (up to two years)[16], [17] and the long - term consequences of exposure to food insecurity early on in life are not well known.