This block is caused by mutations of the gene encoding the γc cytokine receptor subunit of interleukin - 2, -4, -7, -9, and -15 receptors, which participates in the delivery of growth, survival, and differentiation signals to
early lymphoid progenitors.
Not exact matches
One key cell that is an
early initiator of this allergic inflammation is known as a «type 2 innate
lymphoid cell» (ILC2).
«Although it's still
early days for this line of research, these findings provoke the hypothesis that MHCII + innate
lymphoid cells may be an important pathway to therapeutically target in the treatment of some chronic inflammatory diseases,» suggests Sonnenberg.
Innate
lymphoid cells (ILCs) are immune cells that regulate
early immune responses against viruses, bacteria and parasites through the release of soluble factors.
Researchers at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) have discovered that innate
lymphoid cells,
early responders of the immune system, are primed at the DNA level for rapid action.
Early discoveries led researchers to home in on the hematopoietic system, the organs that produce the two kinds of blood cells,
lymphoid and myeloid cells.
Hsiou - Chi Liou and colleagues find that c - Rel, a
lymphoid - specific member of the NF - kappaB / Rel family of transcriptional factors, is essential for B lymphocyte survival and cell cycle progression, [i] and that it is important for inducible cytokine and cytokine receptor expression and a key regulator of
early activation and proliferation in T cells.