Researchers at the Ludwig - Maximilians - University, the German Center for Neurodegenerative Diseases (DZNE), and the Institute for Stroke and Dementia Research (ISD) in Munich, Germany, have identified a brain
inflammation marker in patients at
early asymptomatic stages
of Alzheimer's disease.
Interventions targeting modifiable risk factors (eg, smoking, inactivity, and poor diet) in adult life have only limited efficacy in preventing age - related disease.3, 4 Because
of the increasing recognition that preventable risk exposures in
early life may contribute to pathophysiological processes leading to age - related disease, 5,6 the science
of aging has turned to a life - course perspective.7, 8 Capitalizing on this perspective, this study tested the contribution
of adverse psychosocial experiences in childhood to 3 adult conditions that are known to predict age - related diseases: depression,
inflammation, and the clustering
of metabolic risk
markers, hereinafter referred to as age - related - disease risks.