Sentences with phrase «early oligomeric»
From our point, ROS scavengers as well as mitoprotective strategies might be one part of a complex treatment strategy for AD also comprising drugs lowering the early oligomeric Aß species which all need to be applied decades before the disease is diagnosed.
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Furthermore, in brains from APP transgenic mice conformation - specific antibodies have revealed the early appearance of intraneuronal fibrillar and oligomeric Aβ immunoreactivity, which declined as amyloid plaques appeared, and further became evident in the extracellular space [10].