Sentences with phrase «early onset epilepsy»

Her research interests are directed at improving outcomes in early onset epilepsy, which includes the role of early surgical intervention and the ketogenic diet.

Not exact matches

Lennox - Gastaut syndrome (LGS) or Dravet syndrome (DS) are rare, severe forms of epilepsy with onset in early childhood and poor long - term prognoses.

GW's Epidiolex development is initially concentrating on severe, orphan, early - onset, treatment - resistant epilepsy syndromes including Dravet syndrome, Lennox - Gastaut syndrome (LGS), Tuberous Sclerosis Complex (TSC) and Infantile Spasms (IS).

We were unable to detect any genotype - phenotype correlation, but unlike previously reported cases, most of the DDD patients with STXBP1 pathogenic variants did not present with very early - onset or severe epilepsy and encephalopathy, though all have developmental delay with intellectual disability and most display behavioral problems and suffered seizures in later childhood.

The inherited conditions of aortic stenosis (a narrowing above the aortic heart valve or the aortic valve itself), atopy / allergic dermatitis (skin allergies), gastric dilatation volvulus (bloat / stomach dilation), early onset cataracts (a clouding of the lens inside the eye), dilated cardiomyopathy (enlargement of the chambers of the heart and thinning of the muscle wall), elbow dysplasia (abnormal growth of tissues that leads to malformation and degeneration of the joint), epilepsy (brain seizures), hypothyroidism (underactive production of thyroid hormones), intervertebral disk disease (problems with the disks between the vertebrae of the spine leading to neurological problems), and hepatic portosystemic shunt (an abnormal blood circulation where blood is diverted around the liver rather than into it) are more prevalent in purebred dogs than in mixed - breed.

In contrast, for aortic stenosis, gastric dilation volvulus, early onset cataracts, dilated cardiomyopathy, elbow dysplasia, epilepsy, and portosystemic shunt, the prevalence in most purebred groups was not distinct from that seen in the mixed - breed population.

For aortic stenosis, GDV, early onset cataracts, dilated cardiomyopathy, elbow dysplasia, epilepsy, and portosystemic shunt, most purebred groups were not statistically distinct from the mixed - breed population with higher prevalence in purebreds restricted to distinct subsets of purebred dogs.

Ten disorders studied exhibited a statistically significant elevated prevalence in the purebred population when compared to the mixed - breed population: aortic stenosis, atopy / allergic dermatitis, GDV, early onset cataracts, dilated cardiomyopathy, elbow dysplasia, epilepsy, hypothyroidism, IVDD, and portosystemic shunt [6].

For ten other inherited conditions, the purebred dog population had greater prevalence than that seen in mixed - breeds: aortic stenosis, atopy / allergic dermatitis, gastric dilatation volvulus (GDV), early onset cataracts, dilated cardiomyopathy, elbow dysplasia, epilepsy, hypothyroidism, intervertebral disk disease (IVDD), and portosystemic shunt.