Plenary speakers active in the fields of cancer biology, immunology, and cancer immunotherapy will present on an array of topics, including: new mechanistic perspectives from basic and preclinical research, results from
early phase clinical trials of combination therapies, the durability of treatment responses to CAR - T cell therapies, and managing the known toxicity of effective immunotherapies in clinical trials.
In my role as a Clinical Professor of Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Professor of Medicine and Director of
Early Phase Clinical Trials Program in the Department of Medicine at Roswell Park Comprehensive Cancer Center, I am developing novel therapies for patients with cancer.
An experimental immuno - oncology treatment will move into
early phase clinical trials for patients with advanced solid tumours, including lung cancers, under a collaboration agreement between Cancer Research UK * and Biotecnol Limited.
The Brain and Spinal Tumor Program at the Kimmel Cancer Center is a member of the Adult Brain Tumor Consortium (ABTC), a group of 16 medical centers dedicated to improving treatments for adults with malignant brain tumors by
initiating early phase clinical trials and collaborations with researchers and other clinical trials groups.
The Johns Hopkins Kimmel Cancer Center is one of 11 Lead Academic Organization sites of the National Cancer Institute's Experimental Therapeutics Clinical Trials Network (ETCTN), which supports the evaluation of
early phase clinical trials on experimental therapies.
CDP is a joint initiative between Cancer Research UK's Drug Development Office and Cancer Research Technology, to progress promising anti-cancer agents which pharmaceutical companies do not have the resources to progress
through early phase clinical trials.
Overall, SR - Tiget represents a multi-disciplinary research environment, which provides a unique blend of scientific expertise in the development of innovative gene and cell therapy strategies, access to relevant preclinical models to evaluate their efficacy and safety, as well as competence in
conducting early phase clinical trials.
While a postdoctoral fellow at the Naval Medical Research Institute in Bethesda, he developed a system for large - scale efficient culture of lymphocytes that has proved to be the foundation for over 35
early phase clinical trials of adoptive immunotherapy.
He is working closely with a team of physicians at the UNM Cancer Center to conduct these trials: M. Omar Chohan, MD, a neurosurgeon who specializes in surgery for tumors of the brain and spinal cord; Gregory Gan, MD, PhD, a radiation oncologist who is an expert in the radiation therapy of brain tumors; and Yanis Boumber, MD, PhD, a newly recruited medical oncologist to the UNM Cancer Center who is an expert in cancers of the lung, brain and spinal cord, and
early phase clinical trials.
In August 2014, KalVista Pharmaceuticals Ltd. launched
an early phase clinical trial of a PKal inhibitor to treat DME, with Jennifer Sun, M.D., Ph.D., of Joslin's Beetham Eye Institute as principal investigator.
C2T2 studios bring together a multidisciplinary group of investigators to discuss new ideas for
early phase clinical trials.
To address the challenges involved in this process, the C2T2 brings together
our early phase clinical trials program, precision cancer medicine initiatives, and non-invasive imaging core.
The clinical biostatistics team has strong connection with the Biometry department (Head A. Savignoni),
the early phase clinical trial and precision medicine unit where patients are treated with drugs in development (Head C. Le Tourneau), the translational research department in particular the Circulating Tumor Biomarkers laboratory (Charlotte Proudhon), and of course the other teams of the U900.
As the Director of
the Early Phase Clinical Trials Program at Roswell Park, I am responsible for developing novel therapies for many types of cancer, including melanoma.
Since the program's inception, CVC investigators have treated nearly 700 cancer patients in more than 40
early phase clinical trials of therapeutic cancer vaccines.
My clinical care and research focus on
early phase clinical trials.