The Johns Hopkins Kimmel Cancer Center is one of 11 Lead Academic Organization sites of the National Cancer Institute's Experimental Therapeutics Clinical Trials Network (ETCTN), which supports the evaluation of
early phase clinical trials on experimental therapies.
Not exact matches
White and colleagues will work with other collaborators at the Cancer Institute to develop
early -
phase patient
clinical trials based
on the findings from this study in the near future.
An advisory panel to the FDA recommended approval of Provenge
on the basis of good
early clinical results, but the FDA instead requested more information last May after a second
phase III
clinical trial seemed more equivocal.
Learn more about how we are delivering
on our commitment to leading medicine from the
earliest phase of discovery in a lab to the testing new drugs or therapies in
clinical trials.
Our group has 3 major goals: Develop novel therapeutic approaches based
on centrosomal clustering To further develop our first prototype inhibitors of centrosomal clustering preclinically and to establish a robust and specific high throughput small molecule screen Discover key events in myeloma pathogenesis To investigate the pivotal transition from the pre-malignant, asymptomatic to malignant, symptomatic stages of plasma cell dyscrasias in order to understand the pathophysiology and thereby identify novel targets Translate small molecule therapeutics from bench to
clinical trials To evaluate novel agents in the preclinical setting and to initiate
early phase clinical trials in hematologic malignancies with focus
on multiple myeloma
The drug was approved based
on efficacy and safety results from a
phase III
trial presented
earlier this year at the 2015 American Society of
Clinical Oncology Annual Meeting.
The Center for Cancer Targeted Therapies (C2T2) integrates a
phase I - Ib /
early clinical trials program, a precision cancer medicine infrastructure with expertise
on tumor tissue - based state - of - the - art molecular methods, and a core resource with novel non-invasive functional imaging methods.