Through analyzing several datasets of prostate cancer cases and patient outcomes, the researchers found that a high level of expression of two genes, TOP2A and EZH2, was associated with
early recurrence of prostate cancer and metastatic spread, leading to an increased risk of death.
The approach may offer an improved way to detect
early recurrence of breast cancer in women and men.
Not exact matches
(Note the
recurrence of the expression «seeing as», whose use by Wittgenstein and Wisdom was mentioned
earlier.)
When Harry Kane suffered a
recurrence of an ankle injury picked up
earlier in the season at Millwall last month, Tottenham Hotspur fans were understandably panicked.
Detect any signs
of late effects or even
early recurrence.
VIAM Africa had in an
earlier statement, blamed the
recurrence of such errors on the Ghana Education...
«Mutations that may enable
earlier diagnosis
of colorectal cancer
recurrence identified.»
We will use the unique set
of mutations present in that individual's cancer, as a barcode or thumbprint that we can exploit as innovative diagnostics to monitor for cancer
recurrence and diagnose it
early,» explained Dr Iain Tan, co-lead author
of the study who is a Consultant Medical Oncologist at NCCS and also a clinician scientist at GIS.
Since the detection
of the toxin microcystin left nearly half a million Ohio and Michigan residents without drinking water for several days in
early August, discussions
of ways to prevent a
recurrence have largely focused on the need to reduce the amount
of phosphorus fertilizer that washes off croplands and flows into western Lake Erie to trigger harmful cyanobacteria blooms.
«These findings will give women with
early stage breast cancer greater certainty that anti-estrogen therapy will decrease their risk
of recurrence and increase their chance for survival whereas chemotherapy will not,» said breast cancer survivor Mary Lou Smith, JD, MBA, who helped design the study as a leader in the ECOG - ACRIN Cancer Research Advocates Committee.
Researchers have shown that magnetic resonance imaging (MRI) can detect the
earliest signs
of breast cancer
recurrence and fast - growing tumors.
This suggests that Ga - 68 PSMA PET / CT will be an effective imaging tool for
early detection
of prostate cancer
recurrence.
«The study indicates that screening for silent strokes in children starting school can lead to
early detection and prevention
of recurrences as well as reduction in other complications
of sickle cell anemia such as acute painful episodes and acute chest syndrome.
Therefore, we are planning to use this platform for
early diagnosis as well as
recurrence diagnosis
of diseases such as cancer.»
An
earlier analysis
of diets in the same patient cohort by Fuchs and his colleagues found a significant link between coffee consumption and reduced
recurrence and mortality in colon cancer.
«In this study we've shown five distinct ways — by quantifying tumor burden, identifying disease subtype, cataloging mutations, predicting transformation and providing
early warnings
of recurrence — that circulating tumor DNA can yield potentially clinically useful information,» said Diehn.
The new studies find high activity with investigative drugs for advanced melanoma, and show for the first time that ipilimumab, a treatment already approved for advanced melanoma, can substantially decrease the risk
of melanoma
recurrence in certain patients with
earlier - stage disease.
Anterior insula volume and guilt: neurobehavioral markers
of recurrence after
early childhood major depressive disorder.
«This study demonstrates that Prosigna can reliably identify
early stage breast cancer patients who have a low risk -
of disease
recurrence at 10 years, including a substantial proportion
of patients with node - positive disease for whom the risk / benefit derived for adjuvant chemotherapy would be at best neutral,» said Dr. Alessandra Cesano, chief medical officer
of NanoString Technologies.
«You could assess the patient's response to treatment, alter the regimen if needed, and monitor for any chance
of early recurrence,» she says.
SEATTLE, Feb. 05, 2018 (GLOBE NEWSWIRE)-- NanoString Technologies, Inc. (NASDAQ: NSTG), a provider
of life science tools for translational research and molecular diagnostic products, today announced the publication
of a landmark study in which Danish researchers used the Prosigna ® Breast Cancer Assay risk
of recurrence (ROR) score to accurately predict rates
of 10 - year distant
recurrence (DR)
of cancer in a comprehensive and population - based cohort including all postmenopausal women in Denmark with
early - stage hormone receptor (HR)- positive, Her - 2 negative breast cancer who received 5 years
of adjuvant endocrine therapy according to nationwide guidelines between 2000 and 2003.
In both
early stage non-small cell lung cancer and limited stage small cell lung cancer, we found evidence
of a significant association between continued smoking and
recurrence of the primary tumour; in limited stage small cell lung cancer, we found also evidence
of a substantial elevation in the incidence
of a second primary tumour.
We reviewed 10 observational studies, all
of which showed some evidence that people who continue to smoke after a diagnosis
of early stage lung cancer have an associated higher risk
of recurrence, second primary tumour, or all cause mortality compared with those who stop smoking at that time.
By Patrick Sauer TUESDAY, Dec. 16, 2008 (Health.com)-- Women who have been treated for
early - stage breast cancer may have a lower risk
of recurrence if they eat a relatively low - fat diet that's rich in fruits, vegetables, and fiber, according to a study published Monday in the Journal
of Clinical Oncology.
SATURDAY, May 31 (HealthDay News)-- A drug used to treat osteoporosis lowered the risk
of breast cancer
recurrence in premenopausal women with
early breast cancer.
Guided / recorded awareness exercises directed at increasing nonjudgmental awareness
of bodily sensations, feelings and thoughts Taking on problems with a position
of self - compassion Establishing an «action plan» made up
of strategies for dealing with
early warning signs
of relapse /
recurrence.
Incidence and
recurrence of Neural Tube Defects (serious birth defects
of the spinal cord and the brain which arise during the
early development
of the embryo, most common being spina bifida)
An
earlier study concluded that one year after being treated for back pain, only 30 percent
of a group
of volunteers who performed exercises for multifidus had a
recurrence of pain; 84 percent
of the non-exercising control group still experienced flare - ups
of pain at the one - year mark.
Among these studies are studies on more than 19,000 children representing
of 47,000 patient years
of growth hormone treatment; a prospective study
of 100 adult growth hormone — deficient patients followed for 1 to 4 years, a study
of 910 children treated with growth hormone for 11 years, a study
of 32 adults and children followed for up to 40 years treated with growth hormone (average 10.8 years); a study
of 180 growth hormone — treated children followed for over 6 years with reduced cancer
recurrence risk (RR 0.6); a prospective analysis
of 289 growth hormone — deficient adults who, after 5 years
of growth hormone therapy, showed lower risk
of malignancy (RR 0.25) and decreased risk
of myocardial infarction (RR 0.19) and
early mortality (RR 0.22) compared with the untreated group.
One study conducted by researchers at Women's Healthy Eating and Living (WHEL) followed women who had completed treatment for
early stage breast cancer, and found that women with the highest blood concentrations
of carotenoids had the least likelihood
of cancer
recurrence.
«And while the haunting imagery
of Sept. 11 may have made investors hypersensitive to the
recurrence of disaster — and made
earlier years seem placid by comparison — such macro events aren't unusual at all.
There are various factors that determine the cost
of cancer like the stage
of cancer when it was diagnosed -
early, major, advanced or critical; the cost
of the hospital, duration
of cancer treatment,
recurrence of the disease, loss
of income and extent
of insurance cover already available.
Recurrence of major depression in adolescence and
early adulthood, and later mental health, educational and economic outcomes
The finding
of residual depressive symptoms during recovery has also been reported in adult MDD.44, 45 Longitudinal investigations
of adults with residual depressive symptoms have shown
earlier recurrence and continued impairment in social functioning in follow - up studies.46 - 48 The implications
of this finding will be clarified as this preschool sample is observed into later childhood and
early adolescence.
In the latter stages
of the course patients develop an «action plan» that sets out strategies for responding when they become aware
of early warning signs
of relapse /
recurrence.
As noted by Marryat and Martin (2010) such screening and intervention beyond the
early post-natal period and throughout children's
early years could help improve mental health or prevent
recurrence of problems, possibly resulting in positive child outcomes (or prevention
of negative outcomes).