"Early relapse" refers to the occurrence of a setback or worsening of a condition, such as illness or addiction, shortly after a person has shown signs of improvement. It indicates that the progress made in recovery has been disrupted or reversed at an early stage.
Full definition
Sanford's collaborator at UCLA, Dinesh Rao, was studying B - ALL cases involving chromosomal rearrangements of the mixed lineage leukemia (MLL) gene, which accounts for about 5 percent of B - ALL cases and is associated with poor prognosis and increased risk
of early relapse after treatment.
Now, a new approach that tailors a personalized vaccine to the mutated proteins in an individual's tumor appears to have prevented
early relapses in 12 people with skin cancer.
Using clinical samples from patients, the scientists have confirmed that ER + breast cancer tumours that do not express MSK1 are associated with a risk
of earlier relapse, while those that express this molecule will form metastases later.
CONCLUSION: Carrageenan intake contributed to
earlier relapse in patients with ulcerative colitis in remission.
Scientists at A * STAR's Genome Institute of Singapore (GIS), in collaboration with local clinicians and colleagues in the USA, have identified a biomarker which is strongly associated with triple negative breast cancer (TNBC), a highly aggressive carcinoma that often has
early relapse and metastasis following chemotherapy.
Collaboration with Hematology and Bone Marrow Transplantation Unit research group in molecular diagnostics applied to the management of patients undergoing allogeneic SCT, especially for the detection of minimal residual disease and
early relapse.
«Detection of ctDNA allows identification of a subgroup of patients at high risk of
early relapse and inferior survival, allowing stratification of patients to adjuvant regimens associated with higher toxicity but greater potential for efficacy.»