Early response to treatment predicts remission and recovery at 3 years in people with schizophrenia
Patients that are likely to benefit the most from a given treatment can be selected based on their individual metabolic signatures or
early response to treatment.
Not exact matches
Dan Chen, head of Roche / Genentech's cancer immunotherapy unit, told Fortune the data were particularly promising since they could lead
to Tecentriq becoming a first
response treatment and give additional credence
to the company's argument that immunotherapies are more effective the
earlier they're given
to patients.
Our findings indicate that the
earlier a child is treated for Selective Mutism, the quicker the
response to treatment, and the better the overall prognosis.
The
early - life STAT6 - IP
treatment did not prevent the mice from mounting an immune
response to RSV and clearing the infection.
The authors suggest that HAND2 methylation «could be applied
to triage women who present with postmenopausal bleeding (currently ~ 90 % of women who present with this symptom and are cancer - free must undergo endometrial biopsy for a definitive diagnosis) and could be further employed as a test
to early detect or even predict the risk for endometrial cancer and
response to preventative
treatment.»
This includes determining whether the drugs should be used
earlier on in cancer
treatment, finding biomarkers
to predict
response, and combining immunotherapy with other
treatments.
The imaging system may be able
to predict
response to chemotherapy as
early as two weeks after beginning
treatment.
Genotyping of a population of 329 patients with
early RA revealed just over one - quarter had the allele * 2 HS1, 2 A enhancer, and one in 10 the allele * 1 HS1, 2 A enhancer, which is comparable with previously published data.7 Patients with the allele * 2 genotype had more active disease at the start of
treatment and were significantly less likely
to achieve a good
response and / or remission after three months
treatment than those patients with the allele * 1 genotype.
The trial, named PREVAIL, was concluded
early, after a planned interim analysis, because of overwhelming
response to the
treatment.
«Our study looks at people with recently diagnosed,
early RA, who should have the best outcomes and best
responses to treatment, and sees how many are either overweight or obese, and then determines if those who are overweight or obese have worse outcomes than those with healthy weight,» said Dr. Goodman.
Most research has focused on understanding and managing the late consequences of sepsis while little is known about the changes occurring in the bone marrow at
early stages of the
response to bacterial infection, when the opportunity for effective
treatment might still be available.
In addition
to offering
early evidence of a drug's effectiveness, if depth of
response predicts patient outcomes, then, Doebele says, depth of
response may be a useful goal of
treatment.
«A strategy
to protect the remaining amounts of insulin produced by diabetics in
response to blood sugar levels is an attractive
treatment alternative, particularly in the
early stages of type II diabetes,» said Dr. Seeliger, Assistant Professor in the Department of Pharmacological Sciences at Stony Brook University School of Medicine.
«These splicing signatures could potentially be used as clinical biomarkers
to detect blood stem cells that show signs of
early aging or leukemia, and
to monitor patient
responses to treatment,» said Crews.
The
responses seen in the patients who had acquired resistance
to earlier TKI
treatment but without evidence of T790M mutation was unexpected.
Knowing whether someone is less likely
to be able
to control their emotional
responses could, however, have enormous potential for tailoring drug or behavioural
treatments for people who suffer trauma at an
early age, says Essi Viding of University College London, a psychologist who studies psychopathic violence.
As
early as 4 weeks into
treatment, 21 % in the guselkumab group had a significant
treatment effect on ACR20
response, compared
to zero in the placebo group (p < 0.001).
«You could assess the patient's
response to treatment, alter the regimen if needed, and monitor for any chance of
early recurrence,» she says.
Bertani G, Santoleri L, Ferri U, Marenco P, Grillo G, Zucchetti E, Forno B, Lando G, Scarpati B, Cairoli R, Rossini S, Cesana C.
Response of steroid - refractory chronic graft - versus - host disease
to extracorporeal photopheresis correlates with the dose of CD3 + lymphocytes harvested during
early treatment cycles.
This will allow us
to see the
earliest changes
to these cells, track how they change over time, and monitor their
response to treatments.
Although there is currently no technology that allows
early diagnosis of the disease, a number of putative markers have been identified: their detection after diagnosis would be a useful tool
to monitor the evolution of the tumor during
treatment, providing valuable prognostic information on
response to a given therapy.
It's potential as a biomarker of disease and an
early objective marker of
treatment response is genuine but still
to be realized.Resting - state functional magnetic resonance imaging has made some strides in the clinical realm but significant advances are required before it can be used in a meaningful way at the single - patient level.
Early response to antipsychotic medication is known to be associated with better outcome and fewer subsequent episodes, and intervening early with effective treatments is therefore impor
Early response to antipsychotic medication is known
to be associated with better outcome and fewer subsequent episodes, and intervening
early with effective treatments is therefore impor
early with effective
treatments is therefore important.
Some important studies include: • Beneficial effects of a high carbohydrate, high fiber diet on hyperglycemic diabetic men (1976) •
Response of non-insulin-dependent diabetic patients
to an intensive program of diet and exercise (1982) • Diet and exercise in the
treatment of NIDDM: The need for
early emphasis (1994) • Toward improved management of NIDDM: A randomized, controlled, pilot intervention using a low fat, vegetarian diet (1999) • The effects of a low - fat, plant - based dietary intervention on body weight, metabolism, and insulin sensitivity (2005) • A low - fat vegan diet improves glycemic control and cardiovascular risk factors in a randomized clinical trial in individuals with type 2 diabetes (2006) • A low - fat vegan diet and a conventional diabetes diet in the
treatment of type 2 diabetes: a randomized, controlled, 74 - wk clinical trial (2009) • Vegetarian diet improves insulin resistance and oxidative stress markers more than conventional diet in subjects with Type 2 diabetes (2011) • Glycemic and cardiovascular parameters improved in type 2 diabetes with the high nutrient density (HND) diet (2012)
1935 Effects of the high carbohydrate - low calorie diet upon carbohydrate tolerance in diabetes mellitus 1955 Low - fat diet and therapeutic doses of insulin in diabetes mellitus 1958 Effect of rice diet on diabetes mellitus associated with vascular disease 1976 Beneficial effects of a high carbohydrate, high fiber diet on hyperglycemic diabetic men 1977 Effect of carbohydrate restriction and high carbohydrates diets on men with chemical diabetes 1979 High - carbohydrate, high - fiber diets for insulin - treated men with diabetes mellitus 1981 High carbohydrate high in fibre diet in diabetes 1982
Response of non-insulin-dependent diabetic patients
to an intensive program of diet and exercise 1983 Long - term use of a high - complex - carbohydrate, high - fiber, low - fat diet and exercise in the
treatment of NIDDM patients 1994 Diet and exercise in the
treatment of NIDDM: the need for
early emphasis 1999 Toward improved management of NIDDM: A randomized, controlled, pilot intervention using a lowfat, vegetarian diet 2005 The effects of a low - fat, plant - based dietary intervention on body weight, metabolism, and insulin sensitivity 2006 A low - fat vegan diet improves glycemic control and cardiovascular risk factors in a randomized clinical trial in individuals with type 2 diabetes 2006 Effect of short ‐ term Pritikin diet therapy on the metabolic syndrome 2009 A low - fat vegan diet and a conventional diabetes diet in the
treatment of type 2 diabetes: a randomized, controlled, 74 - wk clinical trial
that keeping a journal is the key
to early diagnosis of problems as well as the best way
to monitor any
treatments or
response to changes such as an new diet, supplement, or remedy.
The
earlier in the course of disease that acupuncture is started and the more numerous and frequent the
treatments, the better the
response tends
to be, and the longer a dis - ease has been present, the longer it will take
to see a positive effect.
Attention should be paid
to these
early signs of arthritis, because
early intervention almost always results in a better
response to treatment and more successful patient outcomes.
The only way
to monitor subclinical renal disease is with bloodwork and urinalysis, at the Veterinary Emergency Hospital we have blood analyzer onsite and in house urinalysis that can help us with
early detection of insulted kidneys and follow their progress and
response to treatment.
«Many cats with severe hypertensive ocular damage present with blindness and bilateral mydriasis resulting from complete retinal detachments and / or intraocular haemorrhage; the changes are often irreversible... Lesions that are not associated with an impaired menace
response or pupillary light deficits... are much more amenable
to anti-hypertensive
treatment... highlighting the importance of
early diagnosis and management.
a. Develop training on animal cruelty and the link between cruelty and domestic violence for law enforcement personnel; b. Expand the current ACO training curriculum; c. Train and educate judges, appropriate court personnel, and prosecutors about animal cruelty; d. Educate veterinarians about recognizing animal cruelty and understanding current law; e. Create a state multidisciplinary team for animal hoarding that would develop an emergency
response system and oversee a task force
to focus on
early intervention of hoarding including mental health counseling in all animal hoarding cases; and create a Department of Mental Health and Department of Corrections forensic assessment protocol for
early intervention, sentencing,
treatment, and rehabilitation; and f. Develop and promote animal cruelty prevention, identification, training and screening tools among pet service providers, associations, and the commercial pet industry.
An
early case like this one frequently has a better
response to treatment.
It also provides a vehicle
to identify symptoms of illness
early and monitor
response to treatment, and provides information on the course of an illness episode.
Our focus on innovative programs, research - supported mental health
treatment and community collaboration has resulted in expansion of mental health, parent support and
early childhood programs
to two locations serving the Greater Long Beach / South Bay area of Los Angeles County,
to several partner schools and Head Starts; home - based services, co-located services at a large children's medical clinic on a hospital campus, and at Carmelitos Housing Community; Sexual Assault
Response Team emergency response for children from birth through 14 years at three Southeast Los Angeles County hospitals, and eight early childhood education - focused child waiting rooms serving Superior Courts across Los Angeles
Response Team emergency
response for children from birth through 14 years at three Southeast Los Angeles County hospitals, and eight early childhood education - focused child waiting rooms serving Superior Courts across Los Angeles
response for children from birth through 14 years at three Southeast Los Angeles County hospitals, and eight
early childhood education - focused child waiting rooms serving Superior Courts across Los Angeles County.