Not exact matches
BioNTech hit the headlines in July when its experimental personalized cancer
vaccine, tailored to the tumors of individual patients, kept disease in check in an
early - stage clinical
trial.
Fiers discovered a key protein on the influenza virus that could serve as a target for a universal
vaccine; the drug has shown promise in an
early clinical
trial.
Ferris, first author of the new study who led
trials of the quadrivalent
vaccine in 2002, says the
earlier, shorter - term evaluation clearly indicated the
vaccine worked.
The company plans in October to conduct a separate test specifically to study the seasonal flu
vaccine's effectiveness among 480 elderly participants (a demographic often encouraged to get seasonal flu shots), and Phase III efficacy
trials across a larger set of demographics are scheduled to begin
early next year.
The results of the
early - stage
vaccine trial suggest that the preventive treatment should be developed further and that scientists are a step closer to being able to counter a potential H7N9 flu pandemic using a clinically tested
vaccine, researchers argue April 30 in Science...
An experimental
vaccine to prevent the mosquito - borne viral illness chikungunya elicited neutralizing antibodies in all 25 adult volunteers who participated in a recent
early - stage clinical
trial conducted by researchers at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.
Early claims for the
vaccine have not been borne out, and the results of full
trials in the US are still awaited.
The Swiss - based pharmaceutical company said that it had made 10 liters of
vaccine that it will use in pre-clinical studies and maybe
early clinical
trials.
«
Vaccine against respiratory syncytial virus shows promise in
early trial: Researchers describe a new approach to developing RSV
vaccines, reporting promising
early results in young children.»
Candidate Zika
vaccines, which have shown
early promise, should be in clinical
trials next year.
For example, although
early clinical
trials of Listeria - based
vaccines have shown that the neutralized bacterium produces only mild flulike symptoms in human patients with cervical cancer, the various methods of genetically disarming the bacteria should be explored to find the safest approach for people gravely ill with pancreatic cancer, because these patients are likely to already have weak immune systems.
The boost was the same investigational
vaccine used in the
earlier VAX003
trial.
The latest
vaccine experiments aim to build on the modest success of a
trial in Thailand in 2009, when an
earlier vaccine showed a 31 percent reduction in infections.
The
vaccine that has been tested in the United States was made from a cold - causing chimpanzee adenovirus that had been engineered to express proteins from two species of the Ebola virus, known as Zaire and Sudan (after their origins), and that was already available when the
trial began in
early September.
An
earlier form of the
vaccine was used in the DarDar
Trial, a seven - year study in Tanzania sponsored by the U.S. National Institutes of Health involving patients with HIV infection who at birth had received BCG, the current tuberculosis
vaccine.
Phase I
trial - an
early clinical
trial designed to study an experimental
vaccine in humans.
A major theme is translational research involving the rapid
early - stage development and assessment of new
vaccines in clinical
trials.
In the RV144
vaccine trial, led by the U.S. Military HIV Research Program at the Walter Reed Army Institute of Research, the efficacy at 3.5 - years was 31.2 %; however, a higher
early effect (60 %) was seen at 12 months.
Burk is doing well, Kopetz says, but it's too
early to report overall results for the seven patients who had customized
vaccines developed initially and have since proceeded to the combination
trial.
A malaria
vaccine has shown promising results in
early stage clinical
trials, a study suggests.
Building on the findings of an
earlier study that found for the first time, albeit modestly, that a
vaccine could prevent HIV infection in 2016, an NIH - supported clinical
trial was launched to test a modified HIV
vaccine.
Because of the
early stage of the
trials, more work is needed to see «if the
vaccines are better than existing treatments, if they improve survival, and what their long - term side effects could be.»
WCBS 880 AM — A «Promising Lead» in Fight Against Pancreatic Cancer - April 4, 2012
Early results from a clinical
trial at CINJ show stable disease in pancreatic cancer for certain candidates following
vaccine treatment.
NJTV - New Pancreatic Study May Offer Hope for the Future - November 17, 2011 CINJ Deputy Director Dr. Edmund Lattime and Co-Director of CINJ's Gastrointestinal - Hepatobiliary Oncology Program Dr. Elizabeth Poplin discuss
early results to a unique clinical
trial that uses
vaccine therapy to target pancreatic cancer.
The department has developed and produced 15 different formulations for
early clinical
trials (e.g.
vaccine antigens produced by heterologous expression) and has conducted more than 20 clinical
trials as sponsor.
A breast cancer
vaccine developed at the School of Medicine is safe in patients with metastatic breast cancer, results of an
early clinical
trial indicate.
Most recently, CRI has launched a new «venture philanthropy» program called the Cancer
Vaccine Acceleration Fund (CVAF) as a means to catalyze development of next - generation therapeutic cancer
vaccines and other immunotherapies by helping to address the critical shortage of capital available for
early stage clinical
trials.
A good knowledge of correlates of protection could predict the efficacy of novel
vaccines at
early stages of development and help identify the most promising candidates for
vaccine trials.
At the International AIDS Society conference in Paris, scientists announced that in an
early - stage clinical
trial, a new HIV
vaccine regimen generated antibody responses in 100 percent of volunteers in most arms of the study.
Last Wednesday, U.S. health officials announced that a potential
vaccine for the Zika virus had entered
early clinical
trials to assess its safety in humans.
In other news, research on a potential
vaccine for the Zika virus entered
early clinical
trials last week.