Not exact matches
«The embryos lack all [
cell types known as] mesoderm and endoderm and are left with skin and some neural tissue, [which derive from the third major
cell type, the
ectoderm].»
But it seemed unlikely, because the body coverings were thought to grow differently: Feathers and hair develop from specialized plates of thickened
ectoderm — an embryonic
cell layer — called anatomical placodes, structures not seen in reptiles.
The
cells originate outside the central nervous system in the
ectoderm of the body wall and appear to migrate to their final locations within the central nervous system by crawling along strands of connective tissue.
The pluripotent
cells of the embryo organize themselves at an early stage in germ layers: the endoderm, mesoderm and
ectoderm.
The answer was yes: They found
cells with markers from all three major body
cell types, called germ layers:
ectoderm (such as nerve
cells), mesoderm (muscle and blood vessel
cells), and endoderm (kidney
cells).
ES
cells are pluripotent, that is, they are able to differentiate into all derivatives of the three primary germ layers:
ectoderm, endoderm, and mesoderm.
It is interesting that YFP - expressing pluripotent
cells were rarely detected in the lens, yet often present in the cornea since the surface
ectoderm forms both the lens and the cornea.
YFP expressing
cells are also observed in the surface
ectoderm and left half of the forebrain (G).
Noggin strongly induces the expression of the EFTFs in frog primitive
ectoderm and human ES
cells [3], [7].
This suggests that the transplanted, control
cells move from the eye field to the surface
ectoderm outside the neural plate.
Additionally, ERCs were reported to be able to differentiate into, or become,
cells from the three different germ layers (see the previous post on MSCs for more details): mesoderm (muscle, bone, fat, cartilage, and endothelial
cells),
ectoderm (neurons), and endoderm (liver, pancreas, and lung
cells)(Meng et al., 2007; Patel et al., 2008).
In one of the experiments, for example, activation of a particular signal at the correct time elicits the appearance of the mesoderm, endoderm and
ectoderm — the precursors of all
cell types — with a spatial organization similar to that of an embryo.
During the process, the
cells begin to form three distinct layers: the endoderm, mesoderm and
ectoderm, determining which tissues or organs the
cells will then develop into.
Histochemical analysis indicated the existence of tissues from all three germ layers, such as neural epithelial
cells (
ectoderm), intestines (endoderm) and muscle (mesoderm)(Figure 6A).
(A) iPS
cells can form embryoid bodies (EB) and can differentiate in vitro to endoderm shown by alpha fetoprotein (AFP)(B), mesoderm shown by smooth muscle actin (SMA) and desmin (D, E), and
ectoderm shown by GFAP and SMI31 staining (G, H).
J, Hematoxylin and eosin staining of teratoma sections generated from integration - free iPSC lines showing differentiation in three germ layers: goblet
cells in gastro - intestinal (GI) tract (endoderm); neural rosettes (
ectoderm) and blood vessels, muscle and cartilage / bone (mesoderm).
Moreover, ES
cell differentiation in vitro recapitulates events that take place during early embryonic development including the formation of the three germ layers of
ectoderm, mesoderm and endoderm, and the emergence of endothelial, hematopoietic, cardiac, neuronal and hepatic or pancreatic
cells [8], [9].
In other words, the basement membrane provides a physical dividing line between
cells descendant from embryonic
ectoderm (epidermis) and embryonic mesoderm (dermis).
Pituitary dwarfism is usually associated with a failure of the oropharyngeal
ectoderm of the cranial pharyngeal duct (Rathke's pouch) to differentiate into trophic - hormone - secreting
cells of the pars distalis.