(A) iPS cells can form embryoid bodies (EB) and can differentiate in vitro to endoderm shown by alpha fetoprotein (AFP)(B), mesoderm shown by smooth muscle actin (SMA) and desmin (D, E), and
ectoderm shown by GFAP and SMI31 staining (G, H).
Not exact matches
«Through studies like that, we've been able to
show how the main so - called germ layers for the embryo are formed —
ectoderm, mesoderm, and endoderm.
As
shown in Figure 4, all three germ layers developed in our cultures as
shown by alphafetoprotein (AFP) for endoderm (Figure 4B), smooth muscle actin (SMA) and desmin for mesoderm (Figure 4D, E), glial fibrillary acid protein (GFAP) and SMI31 for
ectoderm (Figure 4G, H).
J, Hematoxylin and eosin staining of teratoma sections generated from integration - free iPSC lines
showing differentiation in three germ layers: goblet cells in gastro - intestinal (GI) tract (endoderm); neural rosettes (
ectoderm) and blood vessels, muscle and cartilage / bone (mesoderm).