Sentences with phrase «ectopic lipid»

It is now well established that the adipocyte - derived hormone leptin, which is well known for its central role in body weight regulation in part via its control over thermogenesis, 52 — 55 also plays an important role in blood glucose homeostasis and in the protection of insulin - sensitive tissues against excessive ectopic lipid storage by regulating the partitioning of fatty acid away from storage towards oxidation.

Obesity is accompanied by ectopic lipid deposition in multiple tissues, including the skeleton, where infiltration of adipocytes into the bone marrow niche may negatively impact bone formation (7, 8).

Not exact matches

«Participants on the very - high - fat diet also had substantial improvements in several important cardiometabolic risk factors, such as ectopic fat storage, blood pressure, blood lipids (triglycerides), insulin and blood sugar.»

Impaired lipid metabolism with excess release of FA from adipose tissue leads to overspill of circulating lipids and thus to ectopic nonadipose lipid accumulation in the liver hepatocellular lipids (HCL), muscle intramyocellular lipids (IMCL), and myocard myocardial lipids (MYCL) with detrimental consequences of lipotoxicity.

Norwegian researchers found that in addition to not increasing study subjects» risk of heart disease, those on a diet high in fat exhibited «substantial improvements in several important cardiometabolic risk factors, such as ectopic fat storage, blood pressure, blood lipids (triglycerides), insulin and blood sugar.»