Sentences with phrase «effect angiogenesis»

Not exact matches

The study examined the effects of salivary peptide histatin - 1 on angiogenesis (blood vessel formation), which is critical to the efficiency of wound healing.

Thalidomide's penchant for targeting blood vessels in tumors made Mummery wonder whether the drug's effect on angiogenesis could help HHT sufferers.

A fragment of one of the proteins that cancer cells use to exert the clotting effect, called TFPI2, could be used to antagonize blood clotting  therapeutically, they write in Cancer Research. The findings could also have implications for understanding the effects of current medications, such as the angiogenesis inhibitor bevacizumab, also known as Avastin.

If anything, the incomplete recombination of Tie2 in pericytes would have underestimated the effect of Tie2 deletion on tumour angiogenesis.

He is an expert on microvascular anatomy and patterns of angiogenesis and the effects of antiangiogenic agents in blood vessels in different organ and tissue systems.

These findings suggest that MSC transplantation improved DN through direct peripheral nerve angiogenesis, neurotrophic effects, and restoration of myelination.

Mesenchymal stem cells (MSCs) promote angiogenesis in ischemic diseases and have neuroprotective effects, particularly on Schwann cells.

To characterize an anti-angiogenic compound, it is advisable to study its effects on the different steps involved in angiogenesis.

We show for the first time that kahweol is an anti-angiogenic compound with inhibitory effects in two in vivo and one ex vivo angiogenesis models, with effects on specific steps of the angiogenic process: endothelial cell proliferation, migration, invasion and tube formation on Matrigel.

The data presented in this article suggests that tumor subtype needs to be taken into account during treatment design as blocking angiogenesis and therefore increasing tumor hypoxia may be beneficial in the treatment of ER - α — negative breast cancer but could have catastrophic effects on ER - α — positive breast cancer.

These effects included increased appetite, muscle mass, bone mineral density, angiogenesis, VEGF expression, protection of the heart, and modulation of glucose and energy homeostasis.

Mushrooms have quite an array of beneficial properties: Studies on different types of mushrooms have found anti-inflammatory effects, enhanced immune cell activity, prevention of DNA damage, slowed cancer cell growth, and angiogenesis inhibition.

The effects of therapeutic lasers in wound healing include vasodilation, angiogenesis, increased collagen synthesis by fibroblast, differentiation of fibroblast into myofibroblasts, stimulation of leukocytes, and enhanced antioxidant activity.

The physiologic effects of Hyperbaric Oxygen Therapy («HBOT») include improved oxygenation, intravascular and tissue gas bubble reduction, vasoconstriction, increased antimicrobial activity, modulation of inflammation, improved immune function, and angiogenesis.

Some of the proven mechanisms of action include release of endogenous opioids; stimulation of angiogenesis; reduction of the formation of fibrosis; reduction of inflammation; blockage of the effects of reactive oxygen species (ROS) release; neuronal regeneration and functional recovery; enhancement of wound closure; improvement of wound epithelialization, cellular content, granulation tissue formation, and collagen deposition; and bactericidal effects.