Now researchers in the U.S. and Canada want to hold the first anti-aging clinical trial to see if they can replicate the same
effect in humans using a diabetes drug called metformin.
On the basis of those results, at least one company is attempting to replicate
the effect in humans using blood plasma from healthy young people to treat patients with Alzheimer's disease.
Not exact matches
It's a strategy AT&T
used to great
effect in the 1970s to sell long - distance telephony — «Reach out and touch someone» — and again
in the 1990s with a series of spots about distant spouses and overworked moms to sell
human connection
in the nascent digital age.
Although the machines involved are extraordinarily dangerous, the moral principle governing their
use is perfectly ordinary: It is the familiar one that
human beings should engage
in an activity that poses dangers to others only if,
in the totality of the circumstances, doing so is reasonable» i.e., if the good to be achieved, taking account of the probability of success, is proportionate to the possible ill
effects.
Many of its arguments to this
effect are derived from
human rights «data,» which the Administration has
used in turn to justify its support for the contra rebels... [W] e find the Administration's approach to Nicaragua deceptive and harmful....
I was
using the news headlines (and other similar resources, such as charity reports and the like) to make the valid observation that
human evil is universal
in its
effect and nature.
Such a concerted campaign to
use human rights
in justifying military action is without precedent
in U.S. — Latin American relations, and its
effect is an unprecedented debasement of the
human rights cause.24
If humanity is not to be viewed as lord and master of the natural world, with unlimited rights to
use it without regard to the
effects, then what is the place of
human beings
in nature?
We do not know what
effect such prayers will have, but we do know that all generous prayer is valued by God, and while God always does the best that can be done
in every circumstance, we may cherish the thought that God also can
use prayer of that kind for furthering the divine purposes for good, though it may be
in a way past
human comprehension.
God remains powerful, but power — the capacity to influence reality or bring about significant
effects — is redefined through the divine decision to remain defenseless
in the face of our own
human use of power
in order to oppress:
Another
effect that gives cause for alarm is that a man who grows accustomed to the
use of contraceptive methods mayforget the reverence due to a woman, and, disregarding her physical and emotional equilibrium, reduce her to being a mere instrument for the satisfaction of his own desires, no longer considering her as his partner whom he should surround with care and affection... [So]
In preserving intact the whole moral law of marriage, the Church is convinced that she is contributing to the creation of a truly
human civilisation» (HV 17 - 18).
In the part beyond
human conscious, where a person can't instantaneously grasp cause and
effect, that's where faith leads to the poetic and sometimes seemingly delusional metaphors,
used by religion to describe God or whatever aspect is just beyond perception when the person only has incomplete information, but still needs something to help us retain what understanding they're starting to build.
Dr. Nina Kraus, a groundbreaking neuroscientist at Northwestern University, has been studying the
effects of music training on brain development — with the
use of non-invasive approaches
in humans — and on the development of language skills.
Rats are often
used to study how mammalian brains work and many
effects are similar
in human brains.
This sets the standard for the term Natural and stipulates: * Product must be made up of at least 95 percent truly natural ingredients or ingredients that are derived from natural sources * No ingredients with any potential suspected
human health risks * No processes that significantly or adversely alter the purity /
effect of the natural ingredients * Ingredients that come from a purposeful, renewable / plentiful source found
in nature (flora, fauna, mineral) * Processes that are minimal and don't
use synthetic / harsh chemicals or otherwise dilute purity * Non-natural ingredients only when viable natural alternative ingredient are unavailable and only when there are absolutely no suspected potential
human health risks
After the bill came into
effect in February 2005, pro-hunt campaigners sought to contest the Hunting Act
using two legal challenges: the validity of the 1949 Parliament Act; and on the basis that the ban infringed their
human rights.
The European Food Safety Authority plays a vital role
in monitoring the substances
used in manufacturing or growing our food
using the latest scientific evidence to assess whether substances are likely to have harmful
effects on
human or animal health.
Their first visit was to CytoCybernetics, where CEO Glenna Bett explained how her company has developed a system that
uses computers and live
human cells to screen drugs
in their early stages of development, to determine whether they may cause any potentially deadly side
effects.
Chlordane, toxaphene, DDT and PCBs are all examples of persistent organic pollutants — chemicals that were once widely
used in agriculture and manufacturing (or accidentally produced through industrial processes or combustion) but are now banned due to their adverse
effects on
human health and the environment.
Using several techniques to gauge the
effects of these mutations, which are the most common type of variant
in the
human genome, Akey estimated that more than 80 percent are probably harmful to us.
«It would take another two years of training to get the equivalent of my first degree
in Syria,» says Chalati, who is working on ways to
use nanotechnology to deliver drugs into the
human body more efficiently and with fewer side
effects.
This process, which involves
using acid, would normally have the
effect of destroying the HDMPs thus explaining why they have not been recognised before
in humans.
«If you don't
use as close to the total physiological system that you can, you're likely to run into troubles,» like being surprised by side
effects later on
in clinical trials, says William Haseltine, founder and former chairman and CEO of Rockville, Md. — based
Human Genome Sciences.
To demonstrate the
effects of bullying, the researchers
used an animal model simulating the physical and emotional stressors involved
in human bullying — chronic social defeat stress.
Zebrafish are commonly
used to model
human diseases,
in part because their larvae are transparent, making it easy to see the
effects of genetic mutations or drugs.
«We have now found a potential mechanism, and at this point
in our research, we need to test
human participants
in a blinded, placebo controlled clinical study — the same technique we
used to study the behavioral
effects of acupuncture
in rats,» says Eshkevari, a nurse anesthetist and licensed acupuncturist.
Lederman believes that may be because the horsepox virus
used by Jenner evolved during the almost 180 years it was
used, racking up mutations that made it better at replicating
in humans, which led to more serious side
effects.
Much as NASA
used simulators to test dogs and monkeys before launching them into space to gauge the physiological
effects of g - forces and weightlessness, Bond sealed animals, and eventually
human volunteers,
in pressurized tanks to simulate a deep - sea habitat.
The report is replete with examples of the social controversies involving science and technology at that time - the biological and environmental
effects of nuclear weapons testing, DDT and other dioxins, the
use of defoliants and herbicides by the U.S. military
in Vietnam, the safety of nuclear power plants, the ban on fetal research, a moratorium on recombinant DNA research, the need for
human subject protections and informed consent
in genetics research, the misuse of psychology as a tool for torture, the implications of national security controls on science; misconduct
in science, and the role of and protections for whistleblowers - many of which continue to resonate
in the science and society relationship of today.
Similar to the naturally occurring
effects of TET2 mutations
in mice or
humans,
using molecular biology techniques to turn off TET2
in mice caused abnormal stem cell behavior.
Since then, the
effect has been found
in leaves,
human sweat glands and blood — but not
in biological material that could be
used in computers.
The first was to examine the bactericidal
effects of triclosan
in soaps against all 20 strains, and the second compared the ability of antibacterial and non-antibacterial soap to remove bacteria from
human hands, by
using 16 healthy adult volunteers.
Unlike other
human antibodies under investigation that recognize both Zika and the closely related dengue virus, the antibodies
used in this study exclusively target Zika, demonstrating a high specificity that could be important
in avoiding potential side
effects — such as enhanced dengue infection
in regions where both viruses are endemic.
The mice suffered no detectable serious side
effects, although Kay points out that this delivery method can not be
used in humans.
First, the destabilizing
effects of VX - 770 on the corrected CFTR protein might be less robust
in the
human body than were the
effects seen
in lab tests
using human lung cells.
Many people have concerns about the possible
use of genome editing
in humans, for example, about the risks of unintended
effects due to off target DNA alterations, and the implications of making irreversible changes that will be passed on to future generations.
Due to their persistence
in the environment and evidence of
human health
effects, pentaBDE, a specific technical mixture of PBDEs was phased out of
use in couches, mattresses, carpet padding, and other upholstered products beginning
in 2004.
If replicated
in humans, this
effect could significantly delay, and potentially prevent, the need for chronic insulin
use by Type 1 diabetes patients, and help minimize diabetes - related complications.
«
Using a
human voice
in social media has a positive
effect on company reputation: Consumers who follow corporations on social media have a more positive view of them.»
In the lab, the antibiotics had no harmful effect on normal cells, and since they are already approved for use in humans, trials of new treatments should be simpler than with new drugs — saving time and mone
In the lab, the antibiotics had no harmful
effect on normal cells, and since they are already approved for
use in humans, trials of new treatments should be simpler than with new drugs — saving time and mone
in humans, trials of new treatments should be simpler than with new drugs — saving time and money.
To see if PGD and the pentose phosphate pathway were tied to the epigenetic changes the researchers had detected
in distant metastases, they treated tumor cells from different sites
in a single patient with the drug 6 - aminonicotinamide (6AN), which is known to inhibit PGD but is not
used in humans because of its severe side
effects.
«One of our experiments showed that bypassing Lin28a and directly activating mitochondrial metabolism with a small - molecule compound also had the
effect of enhancing wound healing, suggesting that it could be possible to
use drugs to promote tissue repair
in humans.»
While previous investigations into the protein's
effects have
used either mice
in which gene expression was knocked out or transgenic animals that expressed
human gene variants throughout their lifetimes, the MGH - MIND - led study
used a different approach to investigate the
effects of introducing the variant forms of the protein into brains
in which plaque formation had already begun.
The new research focused on just nine genes, those most strongly associated with autism
in recent sequencing studies, and investigated their
effects using precise maps of gene expression during
human brain development.
The researchers are now examining whether CK2 - inhibitors can effectively reduce obesity as well as prevent it, and whether they can be
used alongside next - generation drugs that mimic the
effects of cold to trigger brown fat to burn energy
in humans.
Alison Gopnik, author of «Making AI
Human»
in Scientific American's June issue describes the
use of Bayesian statistics to outline how youngsters infer the basics of cause and
effect.
The researchers
used mouse models that mimic the disease characteristics of pulmonary hypertension and pulmonary fibrosis
in humans to study the
effect of triciribine, which inhibits production of a protein called Akt1.
In the mid-1980s David Wilcove investigated the
effects of
human land
use on songbirds.
MIT engineers have developed new technology that could be
used to evaluate new drugs and detect possible side
effects before the drugs are tested
in humans.
One of those groups is SkyTruth of Shepherdstown, W. Va., founded by geologist John Amos
in 2001 to monitor the
effects of
human activity on the environment
using remote - sensing and mapping technologies.