A potential danger of milk thistle is that it enhances
the effect of chemotherapy drugs, which could lead to chemotherapy toxicity.
But as a result, the tumor is more vulnerable to
the effects of chemotherapy drugs.
Not exact matches
Many laboratory tests were performed and
chemotherapy — requiring intravenous punctures — was resumed, even though studies had shown that this type
of cancer does not respond significantly, if at all, to
drug treatment, and even though complications and side
effects from the
drugs were expected.
Another study from Nigeria published in December
of 2017 is titled Antioxidant and anti-inflammatory
effects of virgin coconut oil supplementation abrogate acute
chemotherapy oxidative nephrotoxicity induced by anticancer
drug methotrexate in rats.
Not all
chemotherapy drugs are equally effective for all people, and finding the best treatment for an individual is a painful process
of trial and error that wastes time and exposes patients to toxic side
effects.
For example, light - activated switches can fine - tune anti-cancer
drugs, so they target only cancer cells and not healthy ones, thereby eliminating the side
effects of chemotherapy.
Exploiting the same pre-clinical model used for their studies, the researchers are testing the efficacy
of this kind
of drug candidates against cancer stem cells, and the possibility
of identifying combination regimens with standard
chemotherapies with minimized toxic
effects, with the perspective
of their possible application for the treatment
of human breast cancer.
A team
of researchers at the University
of Georgia has developed a non-invasive method
of delivering
drugs directly to cancerous tissue using magnetic forces, a form
of treatment that could significantly reduce the toxic side
effects of chemotherapy.
By controlling the timing
of the interaction, researchers could pinpoint delivery
of the
drug to a precise location, thus preventing side common side
effects of chemotherapy, such as hair loss or cardiac toxicity.
The trials for
chemotherapy side
effects — 4
of which were randomized controlled trials — found that medical cannabis was significantly better than anti-nausea
drugs standard at the time
of study for reducing nausea and vomiting.
«Identifying a cancer driver is crucial for cancer treatment because it allows the use
of targeted therapies, which have less side -
effects than conventional
chemotherapy drugs, against a particular protein,» said Kurokawa.
This therapeutic
effect was enhanced by combining the Angiopoietin - 2 antibody with a so - called metronomic
chemotherapy: In this kind
of therapy, chemotherapeutic
drugs are given continuously at much lower dose as in the classical high - dose
chemotherapy.
With the goal
of minimizing the side
effects of chemotherapy on healthy tissues, a team
of researchers at the Center for Self - assembly and Complexity, within the Institute for Basic Science (IBS) have developed novel nanocontainers able to deliver anticancer
drugs at precise timing and location.
Administration
of chemotherapy when a patient's body is at high expression
of drug transporters could improve the body's ability to fend off toxicity and side
effects.
Research by the Baruch S. Blumberg Institute's Pennsylvania Cancer and Regenerative Medicine Research Center suggests that the use
of HIV
drugs can allow for lower doses
of chemotherapy in treating breast cancer, reducing side
effects
Despite the tremendous progress in
drug cancer
chemotherapy, most
of the
drugs used today have a pronounced toxicity
effect, killing normal cells along with cancer cells.
«These studies suggest the potential for dramatically reducing the dose
of chemotherapy or radiation and thereby reducing the side
effects of standard
chemotherapy by enhancing the targeting
of cancer therapies using HIV receptor blocking
drugs.»
«Unlike standard
chemotherapy, HIV - receptor blocking
drugs have been proven to be safe and with rare side
effects,» said Richard G. Pestell, MD, PhD, MBA, President
of the Pennsylvania Cancer and Regenerative Medicine Research Center (PCARMRC).
Since stem cells are also critical for regeneration in the intestine, therapies that target these pathways may further help to design new
drugs that reduce side
effects associated with
chemotherapy, radiotherapy or other causes
of intestinal damage.
The side
effects of immunotherapy are usually quite different from those
of traditional cancer
drugs used in therapies such as
chemotherapy.
The
effects of paclitaxel, a
chemotherapy drug, can be seen on the cellular structures
of the skin
of a larval zebrafish tail fin.
The main drawback
of the anticancer
chemotherapy consists in the lack
of drug selectivity causing severe side
effects.
By learning as much as possible about those unique changes, and developing specific
drugs and therapies to target them, we at City
of Hope believe many cancers can be defeated at the molecular level, often with fewer side
effects compared to traditional
chemotherapy and other treatments.
Xeloda (capecitabine) is just one
of several
chemotherapy drugs that can cause a side
effect known as hand - foot syndrome, in which the palms
of the hands and the soles
of the feet redden and itch.
Many
of the side
effects and health hazards
of Avastin have also been reported for other
chemotherapy drugs.
Another study from Nigeria published in December
of 2017 is titled Antioxidant and anti-inflammatory
effects of virgin coconut oil supplementation abrogate acute
chemotherapy oxidative nephrotoxicity induced by anticancer
drug methotrexate in rats.
A very recent study on the
effects of fasting and calorie restriction on cancer patients receiving
chemotherapy found that calorie restriction and fasting seem to trigger a protective cellular mechanism so strong, that it would be difficult to achieve such an
effect with potent
drug intervention.
One study looked at the
effect of virgin coconut oil when supplemented in a diet high in consumption
of heated vegetable oils, and how virgin coconut oil protected the liver and kidneys, and the other study looked at how virgin coconut oil can reverse the free radical damage done by cancer
chemotherapy drugs.
This lecture will discuss the principles
of administering cancer
chemotherapy, including appropriate
drug selection, dosing, and management
of treatment - related side
effects.
A review
of the management
of chemotherapy side
effects and unique toxicity associated with commonly used
chemotherapy drugs.
Potential adverse side
effects: Bone - marrow suppression leading to reduced numbers
of white blood cells and a risk
of infection, nausea, vomiting, or diarrhea; severe chemical burns if
chemotherapy drugs leak from the vein into surrounding tissues.
Daily online exclusives cover late breaking oncology news, safe handling and administration
of chemotherapy drugs, side
effect management, and new developments in specific cancers.