Not exact matches
Although
thalidomide has been the subject
of hundreds
of studies, we still do not know exactly how it causes its
effects.
Holmes also notes that the relative paucity
of thalidomide births in the United States means that few researchers there can speak with authority on the drug's
effects.
In both zebrafish and chick embryos, adding a version
of cereblon that doesn't bind to
thalidomide seemed to blunt the drug's
effects.
Toxicologist Craig Harris
of the University
of Michigan, Ann Arbor, who has studied
thalidomide's
effects on gene expression, says that the new data are consistent with some theories
of the drug's action, however.