Sentences with phrase «effect on any new relationship»

Not exact matches

Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.

Such risks and uncertainties include, but are not limited to: our ability to achieve our financial, strategic and operational plans or initiatives; our ability to predict and manage medical costs and price effectively and develop and maintain good relationships with physicians, hospitals and other health care providers; the impact of modifications to our operations and processes; our ability to identify potential strategic acquisitions or transactions and realize the expected benefits of such transactions, including with respect to the Merger; the substantial level of government regulation over our business and the potential effects of new laws or regulations or changes in existing laws or regulations; the outcome of litigation, regulatory audits, investigations, actions and / or guaranty fund assessments; uncertainties surrounding participation in government - sponsored programs such as Medicare; the effectiveness and security of our information technology and other business systems; unfavorable industry, economic or political conditions, including foreign currency movements; acts of war, terrorism, natural disasters or pandemics; our ability to obtain shareholder or regulatory approvals required for the Merger or the requirement to accept conditions that could reduce the anticipated benefits of the Merger as a condition to obtaining regulatory approvals; a longer time than anticipated to consummate the proposed Merger; problems regarding the successful integration of the businesses of Express Scripts and Cigna; unexpected costs regarding the proposed Merger; diversion of management's attention from ongoing business operations and opportunities during the pendency of the Merger; potential litigation associated with the proposed Merger; the ability to retain key personnel; the availability of financing, including relating to the proposed Merger; effects on the businesses as a result of uncertainty surrounding the proposed Merger; as well as more specific risks and uncertainties discussed in our most recent report on Form 10 - K and subsequent reports on Forms 10 - Q and 8 - K available on the Investor Relations section of www.cigna.com as well as on Express Scripts» most recent report on Form 10 - K and subsequent reports on Forms 10 - Q and 8 - K available on the Investor Relations section of www.express-scripts.com.

Many new parents worry that bottle feeding will have a negative effect on their breastfeeding relationship.

Even when divorced parents re-marry, the negative effects on children can be detected, perhaps because the necessary investment in a new relationship «crowds out» investment in the children.

The major benefits of Forest School, as listed in the book, «Forest School and Outdoor Learning in the Early Years» by Sara Knight are increased confidence and self - belief; social skills with increased awareness of the consequence of their actions on other people, peers and adults and the ability to work cooperatively; more sophisticated written and spoken language; increased motivation and concentration; improved stamina and gross and fine motor skills; increased respect for the environment and increased observational skills; ability to have new perspectives and form positive relationships with others; a ripple effect to the family.

It might feel like an ideal time to enjoy your new - found sense of freedom, but you have to consider the effects of that relationship on your child.

The researchers caution that their findings, described online on May 4 in npj Schizophrenia — a new publication from Nature Publishing Group — do not establish a cause - and - effect relationship between mental illness and yeast infections but may support a more detailed examination into the role of lifestyle, immune system weaknesses and gut - brain connections as contributing factors to the risk of psychiatric disorders and memory impairment.

The work could throw new light on the brain mechanisms that dictate social standing in people and its effects on anxiety, motivation, addiction and relationships, says Hu.

With that, Dr. Benedetti, using biochemical, cellular and physiological tools, aptly summarizes research new findings on describing the placebo effect on psychology and biology and their impact on the doctor - patient relationship.

The effects of parenthood on mental health are complex, but a new study published in Health Sociology Review reveals a different angle to the relationship: how a person's mental health at 16 influences whether or not he or she becomes a parent, as well as whether or not parenthood has an effect on that mental health going forward.

Studying the modifying effect of maternal depression on pre - and perinatal PPD risk factors sheds new light on the relationship between diabetes and depression.

Susan Amara, USA - «Regulation of transporter function and trafficking by amphetamines, Structure - function relationships in excitatory amino acid transporters (EAATs), Modulation of dopamine transporters (DAT) by GPCRs, Genetics and functional analyses of human trace amine receptors» Tom I. Bonner, USA (Past Core Member)- Genomics, G protein coupled receptors Michel Bouvier, Canada - Molecular Pharmacology of G protein - Coupled Receptors; Molecular mechanisms controlling the selectivity and efficacy of GPCR signalling Thomas Burris, USA - Nuclear Receptor Pharmacology and Drug Discovery William A. Catterall, USA (Past Core Member)- The Molecular Basis of Electrical Excitability Steven Charlton, UK - Molecular Pharmacology and Drug Discovery Moses Chao, USA - Mechanisms of Neurotophin Receptor Signaling Mark Coles, UK - Cellular differentiation, human embryonic stem cells, stromal cells, haematopoietic stem cells, organogenesis, lymphoid microenvironments, develomental immunology Steven L. Colletti, USA Graham L Collingridge, UK Philippe Delerive, France - Metabolic Research (diabetes, obesity, non-alcoholic fatty liver, cardio - vascular diseases, nuclear hormone receptor, GPCRs, kinases) Sir Colin T. Dollery, UK (Founder and Past Core Member) Richard M. Eglen, UK Stephen M. Foord, UK David Gloriam, Denmark - GPCRs, databases, computational drug design, orphan recetpors Gillian Gray, UK Debbie Hay, New Zealand - G protein - coupled receptors, peptide receptors, CGRP, Amylin, Adrenomedullin, Migraine, Diabetes / obesity Allyn C. Howlett, USA Franz Hofmann, Germany - Voltage dependent calcium channels and the positive inotropic effect of beta adrenergic stimulation; cardiovascular function of cGMP protein kinase Yu Huang, Hong Kong - Endothelial and Metabolic Dysfunction, and Novel Biomarkers in Diabetes, Hypertension, Dyslipidemia and Estrogen Deficiency, Endothelium - derived Contracting Factors in the Regulation of Vascular Tone, Adipose Tissue Regulation of Vascular Function in Obesity, Diabetes and Hypertension, Pharmacological Characterization of New Anti-diabetic and Anti-hypertensive Drugs, Hypotensive and antioxidant Actions of Biologically Active Components of Traditional Chinese Herbs and Natural Plants including Polypehnols and Ginsenosides Adriaan P. IJzerman, The Netherlands - G protein - coupled receptors; allosteric modulation; binding kinetics Michael F Jarvis, USA - Purines and Purinergic Receptors and Voltage-gated ion channel (sodium and calcium) pharmacology Pain mechanisms Research Reproducibility Bong - Kiun Kaang, Korea - G protein - coupled receptors; Glutamate receptors; Neuropsychiatric disorders Eamonn Kelly, Prof, UK - Molecular Pharmacology of G protein - coupled receptors, in particular opioid receptors, regulation of GPCRs by kinasis and arrestins Terry Kenakin, USA - Drug receptor pharmacodynamics, receptor theory Janos Kiss, Hungary - Neurodegenerative disorders, Alzheimer's disease Stefan Knapp, Germany - Rational design of highly selective inhibitors (so call chemical probes) targeting protein kinases as well as protein interaction inhibitors of the bromodomain family Andrew Knight, UK Chris Langmead, Australia - Drug discovery, GPCRs, neuroscience and analytical pharmacology Vincent Laudet, France (Past Core Member)- Evolution of the Nuclear Receptor / Ligand couple Margaret R. MacLean, UK - Serotonin, endothelin, estrogen, microRNAs and pulmonary hyperten Neil Marrion, UK - Calcium - activated potassium channels, neuronal excitability Fiona Marshall, UK - GPCR molecular pharmacology, structure and drug discovery Alistair Mathie, UK - Ion channel structure, function and regulation, pain and the nervous system Ian McGrath, UK - Adrenoceptors; autonomic transmission; vascular pharmacology Graeme Milligan, UK - Structure, function and regulation of G protein - coupled receptors Richard Neubig, USA (Past Core Member)- G protein signaling; academic drug discovery Stefan Offermanns, Germany - G protein - coupled receptors, vascular / metabolic signaling Richard Olsen, USA - Structure and function of GABA - A receptors; mode of action of GABAergic drugs including general anesthetics and ethanol Jean - Philippe Pin, France (Past Core Member)- GPCR - mGLuR - GABAB - structure function relationship - pharmacology - biophysics Helgi Schiöth, Sweden David Searls, USA - Bioinformatics Graeme Semple, USA - GPCR Medicinal Chemistry Patrick M. Sexton, Australia - G protein - coupled receptors Roland Staal, USA - Microglia and neuroinflammation in neuropathic pain and neurological disorders Bart Staels, France - Nuclear receptor signaling in metabolic and cardiovascular diseases Katerina Tiligada, Greece - Immunopharmacology, histamine, histamine receptors, hypersensitivity, drug allergy, inflammation Georg Terstappen, Germany - Drug discovery for neurodegenerative diseases with a focus on AD Mary Vore, USA - Activity and regulation of expression and function of the ATP - binding cassette (ABC) transporters

This isn't a new idea — I read a very interesting book on the placebo effect a few years ago that argued, in effect, that the doctor - patient relationship is the most powerful placebo mechanism available to us.

A new Pew Internet report looks at the effect the internet has on couples and their relationship.

You may be worried about getting back into the dating scene after some years or decades away from it, and whether previous relationships might have an effect on how you form new ones.

Dating is a stage of romantic relationships in humans whereby two people meet socially with the aim of each assessing the other's suitability as a As the New Year approaches I've been reflecting on the nature of dating and the demoralizing and distressing effect it often plays in people's

ET caught up with the now clean - shaven Russell and his longtime love, Goldie Hawn, at the Los Angeles premiere of his new action epic, and the happy couple opened up about the effect his massive mustache had on their relationship.

After each battle at camp, players can also upgrade their characters with different Crests made with materials they find on the field, unlocking new combos; passive skills and effects; and character exclusive skills that can only be constructed through items obtained by building up support relationships with other characters.

In a new HD interview, special effects supervisor Colin Chilvers spends 16 minutes weighing in on the production, describing Stanley Donen's approach to the material and his relationship with John Barry, the difficulties of working with the robot and executing miniature FX on a tight budget («In those days, there was no such thing as a big - budget science - fiction movie,» he says), and even the age differential between Douglas and Fawcett.

With a focus on developing teachers in the classroom, the new Marzano Causal Teacher Evaluation Model establishes the direct cause and effect relationship between teaching strategies and student achievement that helps teachers and leaders make the most informed decisions that yield the greatest benefits to students.

Retaining an explicit emphasis in the new standards on including «opportunities for students to study relationships among science, technology, and society» (Hicks et al., 2014, Table 1) would open the door to consideration of a set of issues that every future teacher ought to be thinking about, for example, the power relationships enacted online as manifest through sexism, racism, anti-Semitism, and homophobia; the quality of the discourse and information that circulates there and the effects of rumor on reputation; notions of public and private in a digital age; cyber bullying and suicide; copyright and plagiarism; ethics and professional responsibilities related to social media; and a host of other topics and questions that a critical media literacy approach could raise regarding technology and citizenship education.

Finally, there is mixed evidence on the relationship between formal principal training and professional development programs and school performance, with the caveat that the selection and assignment of New York City principals participating in these programs make it hard to isolate their effects.

He has stated that he is seeking to develop games that «foster the most direct relationship with our fans» and these games will be mostly on replayability and content, which could mean the new company will be thinking along the lines of Mass Effect.

In this exhibition of new figurative work, Cathy Daley deals with the theme of communication and the effect of subjectivity on relationships and understanding.

Early in 1940 we managed to find a small house and for the next three years... I was not able to carve at all... the only sculptures I carried out were some small plaster maquettes for the second «sculpture with colour», and it was not until 1943, when we moved to another house, that I was able to carve this idea... In St Ives I was fortunate enough to have constant contact with artists and writers and craftsmen who lived there, Ben Nicholson my husband, Naum Gabo, Bernard Leach, Adrian Stokes, and there was a steady stream of visitors from London who came for a few days rest, and who contributed in a great measure to the important exchange of ideas and stimulus to creative activity... It was during this time that I gradually discovered the remarkable pagan landscape which lies between St Ives, Penzance and Land's End; a landscape which still has a very deep effect on me, developing all my ideas about the relationship of the human figure in landscape - sculpture in landscape and the essential quality of light in relation to sculpture which induced a new way of piercing the forms to contain colour... The sea, a flat diminishing plane, held within itself the capacity to radiate an infinitude of blues, greys, greens and even pinks of strange hues; the lighthouse and its strange rocky island was an eye; the Island of St Ives an arm, a hand, a face... I used colour and strings in many of the carvings of this time.

East Gallery: Turn the Other Cheek In this exhibition of new figurative work, Cathy Daley deals with the theme of communication and the effect of subjectivity on relationships and understanding.

Adam Chodzko's work weaves new relationships between our value and belief systems, exploring their effect on our communal and private spaces through the documents and fictions that control, describe and guide them.

The new relationship will leverage Shimizu's extensive network of sustainable building services clients to further expand the global reach of the International WELL Building Institute's ™ (IWBI ™) WELL Building Standard ™ (WELL), which is the world's first building standard focused exclusively on the effects of the built environment on human health and well - being.

The so - called Svensmark effect (which concerns the sun's effects on cosmic ray intensity), which skeptics have long thought deserved attention, received new support last week since the effects of solar eruptions on cloud density have now been demonstrated to have a strong statistical relationship despite the UN IPCC's longstanding «let's pretend» that solar variations can and should be ignored.

There is nothing new in questioning the function of, and relationship between, the «selling arrangement», the «insignificant» effects criterion, and the concept of effects «too uncertain and indirect» as limits on the scope of the Treaty freedoms.

It will have no effect on your relationship with your current school / employer (ie: sending it to your new job now does not prevent you from continuing at your current job), but is required for the work you will begin in August.

By way of a refresher, following the implementation of the new data breach sections of PIPEDA, organizations that experience a data breach (referred to in PIPEDA as a «breach of security safeguards») must determine whether the breach poses a «real risk of significant harm» (which may include bodily harm, humiliation, damage to reputation or relationships, loss of employment, business or professional opportunities, financial loss, identity theft, negative effects on the credit record and damage to or loss of property) to any individual whose information was involved in the breach by conducting a risk assessment.

Involvement in mediation reduces conflict and this dispute resolution process can have a positive effect on parental relationships (according to Family Mediation Policy in Practice: A Review of Ontario's New Family Mediation Initiative — Part I 32 C.F.L.Q. 193, footnote 37.).

Southampton, Ontario About Youtuber The Chakra House of Healing Talkshow will be looking into many aspects of healings from releasing ego to learning how your past life can heal your present, however, it will be focusing on and specializing in new healing called «Healing Your Money Esteem» discussing people's relationship with that energy called Money and the many ways it effects us both negatively and positively, whether we have abundance or scarcity.

Life and family events premigration and postmigration have been found to have a profound effect on the health and well - being of immigrant children.1, 2 Risk factors include trauma, separation from parents, nonvoluntary migration, obstacles in the acculturation process, 3 and children who immigrate in their mid - or late teens.1, 4 Research also shows that parents who have experienced or witnessed violence have poorer mental health, 2,5 which is likely to affect parent — child attachment and negatively impact child development and mental health.5 Transitioning to a new country may be beneficial for both parents and children, but it may render new and unexpected constraints in the parent — child relationship (eg, children tend to acculturate to the new country faster than their parents), cause disharmony and power conflicts, 6 — 8 and, subsequently, affect the child's mental health.9

Amy holds a Ph.D. in Social Psychology and studies sexual desire, sexual well - being, and the effects of new media (e.g., Facebook) on relationships.

I would say that the classes are great for people that already have a young child because in reality the class teaches how to have better and more effective communication with your partner with the massive new pressure and stress that comes with raising a new child and the effect it has on the dynamics of the parents» relationship.

You will learn new skills that will have an immediate positive effect on the quality of your relationship with your child.

Similarly the effect of extinguishment on the human rights of Aboriginal people in western New South Wales mandates a policy response that acknowledges the continuing relationship of Aboriginal people to their traditional land and provides a mechanism to ensure the protection, enjoyment and recognition of this relationship.

Family discord, divorce, moving to a new place, parenting style, relationships with the parents, sibling influences and peer influences all can have an effect on a child's behavior.

effects of the Internet / mhealth / social media and information / communication technology on the patient - physician relationship and impact on public health, e.g. the studies investigating how the patient - physician relationship changes as a result of the new ways of getting medical information

The cohabitants were also more than three times more likely than married parents to move on to a cohabiting or marital relationship with a new partner if their relationship did break up.9 Researchers paint a sorry picture of the effect these disruptions have; children suffer emotionally, academically, and financially when they are thrown onto this kind of relationship carousel.10

The effect of newer communication technologies on relationship maintenance and satisfaction in long - distance relationships.

Nonetheless, newer forms of communication technology may also have mixed effects on relationships, including increased opportunities for conflict, tension, and jealousy (Hertlein & Ancheta, 2014; Murray & Campbell, 2015; Neustaedter & Greenberg, 2012; Ruppel, 2015; Schade, Sandberg, Bean, Busby, & Coyne, 2013; Stewart et al., 2014).

Fact: «New partners had little effect on mothers... For fathers, however, cohabiting or visiting with a new partner had a particularly detrimental effect on positive engagement [with their own children]... The difference between single fathers and those who had a new romantic partner is noteworthy, given that both groups were similar in that they lived apart from their child and did not have a romantic relationship with the biological mother... Fathers with a new partner who were engaging less in their children provide an interesting contrast to the result that mothers with a new cohabiting partner reported them to be higher than married, cohabiting, or visiting fathers on positive engagement and instrumental suppoNew partners had little effect on mothers... For fathers, however, cohabiting or visiting with a new partner had a particularly detrimental effect on positive engagement [with their own children]... The difference between single fathers and those who had a new romantic partner is noteworthy, given that both groups were similar in that they lived apart from their child and did not have a romantic relationship with the biological mother... Fathers with a new partner who were engaging less in their children provide an interesting contrast to the result that mothers with a new cohabiting partner reported them to be higher than married, cohabiting, or visiting fathers on positive engagement and instrumental supponew partner had a particularly detrimental effect on positive engagement [with their own children]... The difference between single fathers and those who had a new romantic partner is noteworthy, given that both groups were similar in that they lived apart from their child and did not have a romantic relationship with the biological mother... Fathers with a new partner who were engaging less in their children provide an interesting contrast to the result that mothers with a new cohabiting partner reported them to be higher than married, cohabiting, or visiting fathers on positive engagement and instrumental supponew romantic partner is noteworthy, given that both groups were similar in that they lived apart from their child and did not have a romantic relationship with the biological mother... Fathers with a new partner who were engaging less in their children provide an interesting contrast to the result that mothers with a new cohabiting partner reported them to be higher than married, cohabiting, or visiting fathers on positive engagement and instrumental supponew partner who were engaging less in their children provide an interesting contrast to the result that mothers with a new cohabiting partner reported them to be higher than married, cohabiting, or visiting fathers on positive engagement and instrumental supponew cohabiting partner reported them to be higher than married, cohabiting, or visiting fathers on positive engagement and instrumental support.

8) What will be the effect of the move on extended family relationships in New Jersey, and in the new locatiNew Jersey, and in the new locatinew location;

Infants are dependent on their parents and the quality of their parenting skills, and it is therefore important to support the development of parenting skills in new parents, since lack of parenting skills can have detrimental and long term effects on the infants, such as school failure, behavior problems, relationship problems, substance abuse, and delinquency.

The March Market Update covered the new tariffs on Steel & Aluminum, US's export & import relationship to China, the effect of Hurricane Irma on BVI, and much more.

According to these commenters, the new forms impose several significant changes to how real estate closings are handled, causing dramatic systemic effects on the nature of the relationship among the parties.