Specific inhibition of Vps34 activity in the complex form might differentiate
the effect on autophagy or endocytosis.
With a view to clinical studies (tests on humans) it is important to note that the effects on the tumor vasculature were even observed at chloroquine concentrations that had little
effect on autophagy in the cancer cells.
Not exact matches
In their newly published study, the researchers aimed to investigate the
effect of blocking
autophagy on the infiltration of NK cells in melanoma.
The studies
on autophagy by Yoshinori Ohsumi, which earned him the Nobel Prize in Medicine in 2016, and the discovery of cell cycle regulatory genes for which Leland Hartwell, Timothy Hunt and Paul Nurse received the same award in 2001, including the research of Elizabeth Blackburn, Carol Greider and Jack Szostak
on telomeres, telomerase and its protective
effect on the chromosomes, were all made possible thanks to yeast.
That is why loss of
autophagy in regulatory T cells produces a two-fold
effect on both survival and stability.»
Is there any research
on whether
autophagy has positive
effects for those with auto immune diseases?
And you also get the cellular
autophagy happening, where you're recycling a lot of proteins, which do have anti-aging
effect on your telomeres — telomeres.
Autophagy has gained the attention of researchers who recognize its benefits for managing inflammation, slowing the
effects of aging, and treating various chronic diseases, such as autoimmune disease and cancer — more
on this later!
The possible, but not necessary, negative
effects that
autophagy can have
on us, can be read about
on Caveman Doctor.