Sentences with phrase «effect on chromosome»

Deletion of the fission yeastpot1 + gene has an immediate effect on chromosome stability, causing rapid loss of telomeric DNA and chromosome circularization.

The studies on autophagy by Yoshinori Ohsumi, which earned him the Nobel Prize in Medicine in 2016, and the discovery of cell cycle regulatory genes for which Leland Hartwell, Timothy Hunt and Paul Nurse received the same award in 2001, including the research of Elizabeth Blackburn, Carol Greider and Jack Szostak on telomeres, telomerase and its protective effect on the chromosomes, were all made possible thanks to yeast.

Not exact matches

The boosted genes had three main beneficial effects: improving the efficiency of mitochondria, the powerhouse of cells; boosting insulin production, which improves control of blood sugar; and preventing the depletion of telomeres, caps on chromosomes that help to keep DNA stable and so prevent cells wearing out and ageing.

The boosted genes had three main effects: improving cellular energy efficiency; upping insulin production, which improves control of blood sugar; and preventing the breakdown of caps on chromosomes that help prevent cells wearing out and ageing.

These percentages show that history, and not just natural selection, has a big effect on the human gene pool — and that conquerors tend to spread their Y chromosomes.

When the toddler son of peaceniks pines for a toy army truck, she argues, he is expressing an inborn tendency toward active, physical play that has been shaped by social influences, not by the effects of a «gun gene» on the Y chromosome.

That means it has a stronger effect than if it is active only once on one chromosome in the cell,» Dudley concludes.

Two new analyses of the male sex chromosome have concluded that its genes have vital, wide - reaching effects on every cell in the body

«Knowing now that the Y chromosome can have effects all over the genome, I think it becomes even more important to look at its implications on diseases,» Clark says.

In addition to Alkahest's Alzheimer's trial, a study in South Korea is testing the effects of young blood on older people's strength and the deterioration of their chromosomes.

Many of the allelic effects in the QTL were driven by the two founders with underrepresented subspecific origins, including a QTL on chromosome X for infertility that was driven by the PWK / PhJ haplotype.

We also performed the first example of cross validation using complementary CC resources to verify the effect of sperm curvilinear velocity from the PWK / PhJ haplotype on chromosome 2 in an independent population across multiple generations.

The effect of assortative mating is smaller on the X chromosomes than the autosomes because inheritance of the X in males depends only on the mother's ancestry, not on the mating pair.

Trisomy 21 means that there are three copies of chromosome 21, and while not included in the CNV classification, it demonstrates the effects that can occur when additional gene copies are present on a massive scale.

Practical experience of plant geneticists reveals that most insertions of new DNA in plant chromosome have little effect on other genes (Bouché and Bouchez 2001).

Furthermore, they identified one gene (DYRK1A) on human chromosome 21, whose overdose in trisomy (DS) is responsible for the observed effects.

The exome sequences of 1,535 Kronos and 1,200 Cadenza mutants have been re-sequenced using Illumina next - generation sequencing, the raw data aligned to the IWGSC Chinese Spring chromosome arm survey sequence, mutations identified, and their effects predicted based on the protein annotation available at the Ensembl Plants archive site.

Sex differences describe biology - linked differences between women and men, which are caused by differences in sex chromosomes, sex - specific gene expression of autosomes, sex hormones, and their effects on organ systems (Figure 1)(1, 3).

We have re-sequenced the exome of 1,535 Kronos and 1,200 Cadenza mutants using Illumina next - generation sequencing, aligned this raw data to the IWGSC Chinese Spring chromosome arm survey sequence, identified mutations, and predicted their effects based on the protein annotation available at Ensembl Plants.

Finally, we further validated the effects of GBP1 and GBP2 on size regulation by generating a mutant for both gbp1 and gbp2, which are positioned next each other on the second chromosome.

The researchers observed a sequence variant in a previously unidentified gout susceptibility gene located on chromosome 19 that has a large effect on serum uric acid levels and gout.