Sentences with phrase «effect sequence in»

Led by graduate student Patrick O'Hern, the team at Brown and the University of Cologne in Germany uncovered a complex cause - and - effect sequence in both C. elegans worm and mouse models of SMA.

The emphases in counseling on respect for the orderly cause - effect sequences in the world of the psyche and on the necessity of a person's growing in his responsibility for his own inner life can help to counteract any tendency in spiritual healing to function in ways which encourage magic or the temptation to shift the total responsibility to God.

Not exact matches

The questions are, when they will do it, by how much, in what sequence, for how long, to what level, and with what effect on the markets?

Because of sequence of returns risk, portfolio withdrawals can cause the events in early retirement to have a disproportionate effect on the sustainability of an income strategy.

The primary effect of the Federal Reserve's policy of quantitative easing in recent years was to disrupt that sequence by intentionally encouraging continued yield - seeking speculation despite persistent overvalued, overbought, overbullish conditions.

But I do see the divine priority, God's prevenient guidance, in the event as a whole — the history of Old Testament Israel, the birth, ministry, death and resurrection of Jesus, and the coming into being of his church — and in its effect, which we variously describe as the supreme revelation of God's love, the redemption of the world, the coming into being of the church.15 Indeed it is precisely God's prevenient guidance that makes of this entire historical sequence, including its climax in Jesus, one single event, producing one single effect.

Given that faith, as it is expressed, say, in the letters of Paul, the historian can account plausibly for all that follows, and show how effect followed cause in a sequence as «natural» as such sequences ever are.

The nineteenth century saw the reality of the «historical facts» as consisting largely in names, places, dates, occurrences, sequences, causes, effects — things which fall far short of being the actuality of history, if one understands by history the distinctively human, creative, unique, purposeful, which distinguishes man from nature.

We are dealing in fact with a Whiteheadian type of interacting network, rather than a straightforward linear sequence of cause and effect of the classical materialist kind.

Similarly, Fellaini looked as influential as he did during United's previous best run under Van Gaal where they beat Tottenham Hotspur, Liverpool and Manchester City in a six - game sequence of consecutive wins last season, during which the Belgian was used to bully opposing right - backs and midfielders to great effect.

«These predictive algorithms seem to do a good job when CRISPR is performed in cells or tissues in a dish, but whole genome sequencing has not been employed to look for all off - target effects in living animals,» says co-author Alexander Bassuk, MD, PhD, professor of pediatrics at the University of Iowa.

It's well established, of course, that environmental effects like radiation, which alter the genetic sequences in a sex cell's DNA, can leave a mark on subsequent generations.

With epigenetics we mean such changes in genes that are not determined by changes in the actual DNA sequence, but effects that are superimposed on this, caused for example by environmental effects.

The biggest effects of the genome sequence, according to the poll, have been advances in the tools of the trade: sequencing technologies and computational biology.

As you said it is an extremely small number of differences that you find genetically between humans and chimps, but it is an extremely important one, and what seems to make it so important is that a lot o these differences seem to affect what are in effect regulatory sequences.

You would expect to see it in the regulatory sequences because then the effect of a small change can be huge because you are affecting the timing and maybe the sequence of events in development.

Many are probably simply the consequence of 6 million years of genetic drift, with little effect on body or behavior, whereas other small changes — perhaps in regulatory, noncoding sequences — may have dramatic consequences.

Small changes in the protein sequence of sodium channels of American compared with German cockroaches leave the latter susceptible to a venom that has little effect on the former.

The new research focused on just nine genes, those most strongly associated with autism in recent sequencing studies, and investigated their effects using precise maps of gene expression during human brain development.

Essentially an AOP tells a toxicological story in terms of a logical sequence of causally - linked «key events» that occur at different levels of biological organisation, from perturbations at the molecular scale up to effects occurring in a whole organism or a population.

«What this now means is that complicated effects like color correction, which in a conventional optical system would require light to pass through several thick lenses in sequence, can be achieved in one extremely thin, miniaturized device,» said principal investigator Federico Capasso, the Robert L. Wallace Professor of Applied Physics and Vinton Hayes Senior Research Fellow in Electrical Engineering at Harvard SEAS.

To better understand how changes in diet, lifestyle, and exposure to modern medicine affect primates» guts, a team of researchers led by University of Minnesota computer science and engineering professor Dan Knights, veterinary medicine professor Tim Johnson, and veterinary medicine Ph.D. student Jonathan Clayton, used DNA sequencing to study the gut microbes of multiple non-human primates species in the wild and in captivity as a model for studying the effects of emigration and lifestyle changes.

This study further investigated the impact of nicotine use / smoking status and variation in the mu opioid receptor gene (OPRM1), specifically, an A118G single nucleotide polymorphism (SNP, or DNA sequence variation), on the effects of naltrexone on a range of drinking outcomes.

They found that the positive effect on specific mRNA translation was mediated by a sequence embedded in the antisense lncRNA.

Another dogma in cell biology seems about to be toppled: If a mutation in a gene doesn't change the basic sequence of building blocks, then it has no effect.

Here, the authors have done the difficult and time - consuming work of (1) exhaustive sequencing to identify the possible functional variants, and (2) in vivo functional assays to prove that the implicated variants have a phenotypic effect.

Such estimates of ancient divergence times could contain substantial error caused by uncertainty of the molecular clock assumptions, confounding effects of horizontal gene transfer, and errors in estimating sequence homology (i.e., similarlity).

g (acceleration due to gravity) G (gravitational constant) G star G1.9 +0.3 gabbro Gabor, Dennis (1900 — 1979) Gabriel's Horn Gacrux (Gamma Crucis) gadolinium Gagarin, Yuri Alexeyevich (1934 — 1968) Gagarin Cosmonaut Training Center GAIA Gaia Hypothesis galactic anticenter galactic bulge galactic center Galactic Club galactic coordinates galactic disk galactic empire galactic equator galactic habitable zone galactic halo galactic magnetic field galactic noise galactic plane galactic rotation galactose Galatea GALAXIES galaxy galaxy cannibalism galaxy classification galaxy formation galaxy interaction galaxy merger Galaxy, The Galaxy satellite series Gale Crater Galen (c. AD 129 — c. 216) galena GALEX (Galaxy Evolution Explorer) Galilean satellites Galilean telescope Galileo (Galilei, Galileo)(1564 — 1642) Galileo (spacecraft) Galileo Europa Mission (GEM) Galileo satellite navigation system gall gall bladder Galle, Johann Gottfried (1812 — 1910) gallic acid gallium gallon gallstone Galois, Évariste (1811 — 1832) Galois theory Galton, Francis (1822 — 1911) Galvani, Luigi (1737 — 1798) galvanizing galvanometer game game theory GAMES AND PUZZLES gamete gametophyte Gamma (Soviet orbiting telescope) Gamma Cassiopeiae Gamma Cassiopeiae star gamma function gamma globulin gamma rays Gamma Velorum gamma - ray burst gamma - ray satellites Gamow, George (1904 — 1968) ganglion gangrene Ganswindt, Hermann (1856 — 1934) Ganymede «garbage theory», of the origin of life Gardner, Martin (1914 — 2010) Garneau, Marc (1949 ---RRB- garnet Garnet Star (Mu Cephei) Garnet Star Nebula (IC 1396) garnierite Garriott, Owen K. (1930 ---RRB- Garuda gas gas chromatography gas constant gas giant gas laws gas - bounded nebula gaseous nebula gaseous propellant gaseous - propellant rocket engine gasoline Gaspra (minor planet 951) Gassendi, Pierre (1592 — 1655) gastric juice gastrin gastrocnemius gastroenteritis gastrointestinal tract gastropod gastrulation Gatewood, George D. (1940 ---RRB- Gauer - Henry reflex gauge boson gauge theory gauss (unit) Gauss, Carl Friedrich (1777 — 1855) Gaussian distribution Gay - Lussac, Joseph Louis (1778 — 1850) GCOM (Global Change Observing Mission) Geber (c. 720 — 815) gegenschein Geiger, Hans Wilhelm (1882 — 1945) Geiger - Müller counter Giessler tube gel gelatin Gelfond's theorem Gell - Mann, Murray (1929 ---RRB- GEM «gemination,» of martian canals Geminga Gemini (constellation) Gemini Observatory Gemini Project Gemini - Titan II gemstone gene gene expression gene mapping gene pool gene therapy gene transfer General Catalogue of Variable Stars (GCVS) general precession general theory of relativity generation ship generator Genesis (inflatable orbiting module) Genesis (sample return probe) genetic code genetic counseling genetic disorder genetic drift genetic engineering genetic marker genetic material genetic pool genetic recombination genetics GENETICS AND HEREDITY Geneva Extrasolar Planet Search Program genome genome, interstellar transmission of genotype gentian violet genus geoboard geode geodesic geodesy geodesy satellites geodetic precession Geographos (minor planet 1620) geography GEOGRAPHY Geo - IK geologic time geology GEOLOGY AND PLANETARY SCIENCE geomagnetic field geomagnetic storm geometric mean geometric sequence geometry GEOMETRY geometry puzzles geophysics GEOS (Geodetic Earth Orbiting Satellite) Geosat geostationary orbit geosynchronous orbit geosynchronous / geostationary transfer orbit (GTO) geosyncline Geotail (satellite) geotropism germ germ cells Germain, Sophie (1776 — 1831) German Rocket Society germanium germination Gesner, Konrad von (1516 — 1565) gestation Get Off the Earth puzzle Gettier problem geyser g - force GFO (Geosat Follow - On) GFZ - 1 (GeoForschungsZentrum) ghost crater Ghost Head Nebula (NGC 2080) ghost image Ghost of Jupiter (NGC 3242) Giacconi, Riccardo (1931 ---RRB- Giacobini - Zinner, Comet (Comet 21P /) Giaever, Ivar (1929 ---RRB- giant branch Giant Magellan Telescope giant molecular cloud giant planet giant star Giant's Causeway Giauque, William Francis (1895 — 1982) gibberellins Gibbs, Josiah Willard (1839 — 1903) Gibbs free energy Gibson, Edward G. (1936 ---RRB- Gilbert, William (1544 — 1603) gilbert (unit) Gilbreath's conjecture gilding gill gill (unit) Gilruth, Robert R. (1913 — 2000) gilsonite gimbal Ginga ginkgo Giotto (ESA Halley probe) GIRD (Gruppa Isutcheniya Reaktivnovo Dvisheniya) girder glacial drift glacial groove glacier gland Glaser, Donald Arthur (1926 — 2013) Glashow, Sheldon (1932 ---RRB- glass GLAST (Gamma - ray Large Area Space Telescope) Glauber, Johann Rudolf (1607 — 1670) glaucoma glauconite Glenn, John Herschel, Jr. (1921 ---RRB- Glenn Research Center Glennan, T (homas) Keith (1905 — 1995) glenoid cavity glia glial cell glider Gliese 229B Gliese 581 Gliese 67 (HD 10307, HIP 7918) Gliese 710 (HD 168442, HIP 89825) Gliese 86 Gliese 876 Gliese Catalogue glioma glissette glitch Global Astrometric Interferometer for Astrophysics (GAIA) Global Oscillation Network Group (GONG) Globalstar globe Globigerina globular cluster globular proteins globule globulin globus pallidus GLOMR (Global Low Orbiting Message Relay) GLONASS (Global Navigation Satellite System) glossopharyngeal nerve Gloster E. 28/39 glottis glow - worm glucagon glucocorticoid glucose glucoside gluon Glushko, Valentin Petrovitch (1908 — 1989) glutamic acid glutamine gluten gluteus maximus glycerol glycine glycogen glycol glycolysis glycoprotein glycosidic bond glycosuria glyoxysome GMS (Geosynchronous Meteorological Satellite) GMT (Greenwich Mean Time) Gnathostomata gneiss Go Go, No - go goblet cell GOCE (Gravity field and steady - state Ocean Circulation Explorer) God Goddard, Robert Hutchings (1882 — 1945) Goddard Institute for Space Studies Goddard Space Flight Center Gödel, Kurt (1906 — 1978) Gödel universe Godwin, Francis (1562 — 1633) GOES (Geostationary Operational Environmental Satellite) goethite goiter gold Gold, Thomas (1920 — 2004) Goldbach conjecture golden ratio (phi) Goldin, Daniel Saul (1940 ---RRB- gold - leaf electroscope Goldstone Tracking Facility Golgi, Camillo (1844 — 1926) Golgi apparatus Golomb, Solomon W. (1932 — 2016) golygon GOMS (Geostationary Operational Meteorological Satellite) gonad gonadotrophin - releasing hormone gonadotrophins Gondwanaland Gonets goniatite goniometer gonorrhea Goodricke, John (1764 — 1786) googol Gordian Knot Gordon, Richard Francis, Jr. (1929 — 2017) Gore, John Ellard (1845 — 1910) gorge gorilla Gorizont Gott loop Goudsmit, Samuel Abraham (1902 — 1978) Gould, Benjamin Apthorp (1824 — 1896) Gould, Stephen Jay (1941 — 2002) Gould Belt gout governor GPS (Global Positioning System) Graaf, Regnier de (1641 — 1673) Graafian follicle GRAB graben GRACE (Gravity Recovery and Climate Experiment) graceful graph gradient Graham, Ronald (1935 ---RRB- Graham, Thomas (1805 — 1869) Graham's law of diffusion Graham's number GRAIL (Gravity Recovery and Interior Laboratory) grain (cereal) grain (unit) gram gram - atom Gramme, Zénobe Théophile (1826 — 1901) gramophone Gram's stain Gran Telescopio Canarias (GTC) Granat Grand Tour grand unified theory (GUT) Grandfather Paradox Granit, Ragnar Arthur (1900 — 1991) granite granulation granule granulocyte graph graph theory graphene graphite GRAPHS AND GRAPH THEORY graptolite grass grassland gravel graveyard orbit gravimeter gravimetric analysis Gravitational Biology Facility gravitational collapse gravitational constant (G) gravitational instability gravitational lens gravitational life gravitational lock gravitational microlensing GRAVITATIONAL PHYSICS gravitational slingshot effect gravitational waves graviton gravity gravity gradient gravity gradient stabilization Gravity Probe A Gravity Probe B gravity - assist gray (Gy) gray goo gray matter grazing - incidence telescope Great Annihilator Great Attractor great circle Great Comets Great Hercules Cluster (M13, NGC 6205) Great Monad Great Observatories Great Red Spot Great Rift (in Milky Way) Great Rift Valley Great Square of Pegasus Great Wall greater omentum greatest elongation Green, George (1793 — 1841) Green, Nathaniel E. Green, Thomas Hill (1836 — 1882) green algae Green Bank Green Bank conference (1961) Green Bank Telescope green flash greenhouse effect greenhouse gases Green's theorem Greg, Percy (1836 — 1889) Gregorian calendar Grelling's paradox Griffith, George (1857 — 1906) Griffith Observatory Grignard, François Auguste Victor (1871 — 1935) Grignard reagent grike Grimaldi, Francesco Maria (1618 — 1663) Grissom, Virgil (1926 — 1967) grit gritstone Groom Lake Groombridge 34 Groombridge Catalogue gross ground, electrical ground state ground - track group group theory GROUPS AND GROUP THEORY growing season growth growth hormone growth hormone - releasing hormone growth plate Grudge, Project Gruithuisen, Franz von Paula (1774 — 1852) Grus (constellation) Grus Quartet (NGC 7552, NGC 7582, NGC 7590, and NGC 7599) GSLV (Geosynchronous Satellite Launch Vehicle) g - suit G - type asteroid Guericke, Otto von (1602 — 1686) guanine Guiana Space Centre guidance, inertial Guide Star Catalog (GSC) guided missile guided missiles, postwar development Guillaume, Charles Édouard (1861 — 1938) Gulf Stream (ocean current) Gulfstream (jet plane) Gullstrand, Allvar (1862 — 1930) gum Gum Nebula gun metal gunpowder Gurwin Gusev Crater gut Gutenberg, Johann (c. 1400 — 1468) Guy, Richard Kenneth (1916 ---RRB- guyot Guzman Prize gymnosperm gynecology gynoecium gypsum gyrocompass gyrofrequency gyropilot gyroscope gyrostabilizer Gyulbudagian's Nebula (HH215)

Methodology challenges in studying human gut microbiota — effects of collection, storage, DNA extraction and next generation sequencing technologies — Marina Panek — Scientific Reports

This effect results in a broadening of the main sequence band because stars are observed at random stages in their lifetime.

He is interested in elucidating mechanisms of human disease by exploring the functional effects of genetic variation through computational analysis of «- omic» sequencing data.

Digenome - seq is an in vitro nuclease - digested whole - genome sequencing to profile genome - wide nuclease off - target effects in cells.

Our work combines computational analysis of high - throughput sequencing data, population genetics, and experimental work.We focus in particular on studying genetic effects on the transcriptome traits, which has further applications in other traits at the cellular and individual level.

The complete genome sequence has revealed an unusual breadth (in number and in effect) of DNA inversion events that potentially control expression of many different components, including surface and secreted components, regulatory molecules, and restriction - modification proteins.

Removal of artificial sweeteners and their effects on microbial communities in sequencing batch reactors.

The white dwarf must be in a binary system with a main sequence companion so that the amount the total shift due to the ordinary doppler effect can be determined and subtracted out.

In total, this third call will provide 30 million SEK in support for sequence analysis of unique and well - characterized sample collections to study either the genetic basis of disease or environmental effects on biodiversitIn total, this third call will provide 30 million SEK in support for sequence analysis of unique and well - characterized sample collections to study either the genetic basis of disease or environmental effects on biodiversitin support for sequence analysis of unique and well - characterized sample collections to study either the genetic basis of disease or environmental effects on biodiversity.

The researchers were able to predict the direction of this effect with high accuracy, based on the sequences of bacteria present and the resistance genes they carried in samples taken before treatment.

In particular, genome - wide sequencing studies have detected somatic mutations in one or more Eph receptors in 25 % -45 % of melanomas, 15 % -45 % of lung cancers, 25 - 40 % of colorectal cancers and 12 % -25 % of head and neck and uterine cancers (Figure 2), but very limited information is available on the effects of the mutationIn particular, genome - wide sequencing studies have detected somatic mutations in one or more Eph receptors in 25 % -45 % of melanomas, 15 % -45 % of lung cancers, 25 - 40 % of colorectal cancers and 12 % -25 % of head and neck and uterine cancers (Figure 2), but very limited information is available on the effects of the mutationin one or more Eph receptors in 25 % -45 % of melanomas, 15 % -45 % of lung cancers, 25 - 40 % of colorectal cancers and 12 % -25 % of head and neck and uterine cancers (Figure 2), but very limited information is available on the effects of the mutationin 25 % -45 % of melanomas, 15 % -45 % of lung cancers, 25 - 40 % of colorectal cancers and 12 % -25 % of head and neck and uterine cancers (Figure 2), but very limited information is available on the effects of the mutations.

Effect of sequence variants on variance in glucose levels predicts type 2 diabetes risk and accounts for heritability.

The researchers observed a sequence variant in a previously unidentified gout susceptibility gene located on chromosome 19 that has a large effect on serum uric acid levels and gout.

Together these studies suggest that Punc - 7S drives expression of UNC - 7S in a subset of neurons (including AVA and AVB, but not motor neurons) that can effect rescue of forward locomotion, and promoter sequences upstream of exon 2 drive additional expression of UNC - 7S in motor neurons or possibly other neurons required to fully rescue all unc - 7 locomotory defects.

Tillmann, B. & Bigand, E. Global context effect in normal and scrambled musical sequences.

Genome editing technology enables precise modification of individual protein coding genes, as well as noncoding regulatory sequences, enabling the elucidation of functional effects in human disease relevant cellular systems.

Previous studies on processing hierarchical structures in music argued that humans can differentiate between auditory tone sequences generated according to a hierarchical recursive rule and an iterative rule12, show priming effects in integrating harmonic contextual information13, 14, and discriminate between grammatical and ungrammatical transformations in serialist music15, 16.

A limitation in comparing sequences with two levels of embedding against one is the inclusion of an extra pair of motifs that necessitates a longer sequence duration, which confounds distance and item effects.

In this study, the research team searched for gene mutations - or other variations in the genome - that may have a direct effect on the risk of pathologically low - bone density among a large set of sequence variantIn this study, the research team searched for gene mutations - or other variations in the genome - that may have a direct effect on the risk of pathologically low - bone density among a large set of sequence variantin the genome - that may have a direct effect on the risk of pathologically low - bone density among a large set of sequence variants.

«Those DNA sequences were put into the mutant; this allows you to test the effect of the gene if it is only switched on in a specific layer.»

To systematically investigate the effect of P. locustae on the phase change of L. migratoria manilensis, we used a high - throughput sequencing platform (HiSeq 2500; Illumina) to compare gene expression in healthy locusts and locusts infected by P. locustae.

How you breathe in any given sequence can have some pretty dramatic effects!