Sentences with phrase «effective antibodies»

Because survivors of an Ebola infection would typically have produced effective antibodies against the virus (otherwise they wouldn't have survived), transfusions of their blood into a newly infected individual may help that person survive the often fatal disease.
A more effective antibody cocktail could induce a stronger immune response, require a smaller dose, or fight the other species of Ebola as well.
Generally, as B cells divide in response to a pathogen like HIV, genes that produce infection - fighting antibodies mutate, and descendant cells producing the most effective antibodies predominate.
The findings help explain why people infected with HIV can not sufficiently clear the virus with effective antibodies.
The researchers believe this difference in B cell distribution among those with uncontrolled HIV adds to a list of reasons most people do not make effective antibodies against the virus.
The Swiss team isolated a series of monoclonal antibodies from individuals who were protected from one of these experimental vaccines (Sanaria PfSPZ Vaccine) and found that the most effective antibodies recognized a distinct region within the surface protein of the sporozoites that has not been considered in malaria vaccines so far.
Working with highly effective antibodies for which sequences were provided by HUMABS, the Weiner lab is optimizing DMAbs for high levels of expression, binding, and neutralization.
«We may want to put in two or more effective antibodies at the same time to put additional pressure on the virus, so the more good antibodies we can find, the better,» Johnson says.
At Rinat, Van Blarcom focuses on designing, building, and using sequence libraries to discover more effective antibodies.
At the time, Janeway was arguing that antibodies have a big drawback: it takes days for the immune system to develop an effective antibody against a new invader.
The vaccine generated a pool of TH1 CD4 + T cells (also called helper T cells) that are necessary for an effective antibody response as well as a stable pool of CD8 + T memory cells.
Future candidate vaccines are therefore likely to include this glycan cluster among their specific viral targets in order to maximize the chances of stimulating an effective antibody response.
These studies provide insight into the dynamic nature of B cell metabolism that literally «fuels» differentiation in the germinal center to produce an effective antibody response»
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