It is a very potent and
effective drug against Leishmania spp., but is mainly used in case of meglumine antimoniate resistance, among others due to its toxic potential.
«We need to do everything we can to find
effective drugs against the Zika virus, as changes in travel and climate have caused more tropical diseases to move into new parts of the globe,» said Kao, who has also spent 15 years studying the virus that causes hepatitis C.
More knowledge about the mechanisms behind this correlation could be important for developing more
effective drugs against subgroups of glioblastoma.
Not exact matches
Taking this
drug daily has shown to offer more than 90 % (and as much as 99 %)
effective protection
against HIV in clinical trials, and certain New Zealand residents will soon be able to get a three - month supply for just $ 5 (oh, and that's five New Zealand dollars, which is about $ 3.64 in U.S. money).
«The current messages saying that bed sharing is dangerous only if you or your partner are smokers, have been drinking alcohol or taking
drugs that make you drowsy, are very tired or the baby is premature or of low - birth weight, are not
effective,» the authors wrote in the study, adding that doctors need to «take a more definitive stance
against bed sharing for babies under three months».
In his words, «The wide acceptance of NYSC Scheme both at the national and international levels is borne out by the noteworthy contribution of Corps members to such exercises as the electoral process, the
effective nationwide campaign
against HIV / AIDs, Road accidents,
Drug Abuse, Human Trafficking, Corruption, Illiteracy and the implementation of various aspects of the SDGs programme.
A new study explains how a widely used
drug is
effective against inflammatory bowel disease and rejection of bone marrow transplants, while suggesting another way to address both health issues.
He hopes they can develop an antiviral
drug that will be
effective against the entire family of paramyxovirus.
A vaccine
against rotavirus, a highly contagious bug that causes life - threatening diarrhea in young children, was deemed safe and
effective by a U.S. Food and
Drug Administration (FDA) advisory panel on Friday.
One of the greatest challenges in modern medicine is developing
drugs that are highly
effective against a target, but with minimal toxicity and side - effects to the patient.
A
drug that releases two gases to protect the stomach lining may be significantly more
effective than daily aspirin in protecting
against cancer
This could make the
drug effective against autoimmune disease.
He and his team concluded that the
drug was
effective against complications of flu, like pneumonia, thus encouraging its use.
The researchers also identified
drugs that are
effective against the cancers and could potentially be used in the fight to save the devils from extinction.
«Genes may cause tumor aggressiveness,
drug resistance in African - American prostate cancer: Research found many targeted therapies for prostate cancer may not be
effective against tumors in African - American men.»
To make a compound work better
against a specific disease target, medicinal chemists optimize the
drug, tweaking its structure or physical properties to make it more
effective and safer.
«New
drug proves
effective against antibiotic - resistant «superbugs».»
Lab results are impressive: the
drug is as
effective against the 26th generation as it is
against the first.
«Antibiotic
effective against drug - resistant bacteria in pediatric skin infections.»
Bioengineers from Queen Mary University of London (QMUL) have shown for the first time that lithium chloride, a common
drug used to treat mental health disorders, could offer an
effective treatment
against osteoarthritis by disrupting the length of the cells» antennae called primary cilia.
Checkpoint inhibitors already produce unprecedented rates of long - term remission for a handful of hard - to - treat cancers, but their potential is even greater: Because such
drugs modify the body's response to cancer, rather than the cancer itself, they could theoretically be
effective against almost any kind of malignancy.
More important, the
drugs are not much more
effective against depression than are sugar pills, he says.
In contrast to viral proteins, the host targets are less prone to mutations and thus
drugs targeting them could be more
effective against viruses, which mutate easily.
When all the evidence is weighed together, Prozac, Paxil, and other such popular pills seem to be at best weakly
effective against depression — an argument Kirsch presses in his new book, The Emperor's New
Drugs.
Tulane University researchers have developed a new
drug that is
effective against non-severe cases of malaria, according to results from an FDA - supervised clinical trial published in the latest issue of The Lancet Infectious Diseases.
Using virtual tissue technology, researchers at Indiana University have identified a potential new
drug target in the fight
against polycystic kidney disease, an illness with no
effective FDA - approved treatment that affects 200,000 people per year in the United States.
Co-senior study investigator and cancer biologist Iannis Aifantis, PhD, says the study offers the first evidence that «
drugs targeting and disrupting leukemia cells» microenvironment — or what goes on around them — could prove
effective against the disease.»
For example, the study defined cases of pancreatic cancer that are driven by a gene called BRAF, for which there are FDA - approved
drugs, and showed that such
drugs were selectively
effective against BRAF - mutated pancreatic cancer cells.
A new paper published in the journal Science Translational Medicine describes the discovery and biological profiling of an exciting new anti-malarial clinical
drug candidate, MMV390048,
effective against resistant strains of the malaria parasite, and across the entire parasite lifecycle, with the potential to cure and protect in a single dose.
In research published in BioMetals, UJ3 is shown to be as
effective against human esophageal cancer cells, as a widely - used chemotherapy
drug in use today.
A subsidy program intended to drive down the cost of lifesaving malaria
drugs called artemisinin - based combination therapies — now considered the most
effective treatment
against the parasitic disease — was unveiled today in Norway.
The other study showed how using a combination of
drugs at increased potency could prove an
effective therapy
against glioblastoma by inhibiting the PI3K and MAPK cellular pathways.
The compound isn't
effective against so - called Gram - negative bacteria, increasingly feared in hospitals for their resistance to existing
drugs.
What's more, the women in both the heparin and control groups also received injections of the
drug for 42 days after birth, potentially helping to protect them
against blood clots that may manifest themselves at that point, but possibly diluting the results — making it appear that heparin was not as
effective as it may have been.
Because it more effectively induces cancer cell apoptosis in p53 - deficient tumors, FL118 is especially
effective against late - stage cancers, which usually lose functional p53 and are resistant to DNA - damage
drugs.
The targets of these
drugs were not know to be present in cancer cells and therefore no one had considered the possibility that these
drugs might be
effective against aggressive cancer types, says Professor Ivaska.
In theory,
drugs targeting CXCR4 would be an
effective addition to the arsenal
against HIV.
Although there remains no cure for Alzheimer's, researchers hope that testing potential
drugs or therapies prior to mental decline will prove to be more successful than previous attempts at finding the most
effective treatment in the battle
against the debilitating disease.
A team of biologists from San Diego State University has developed a platform for identifying
drugs that could prove to be
effective against a variety of viral diseases.
No e-cigarette company has submitted an application to the U.S. Food and
Drug Administration to approve e-cigarettes for smoking cession, and the FDA has not taken any action
against companies that claim e-cigarettes are
effective for quitting smoking.
To make things worse, no antiviral
drugs currently available have proven
effective against it, and because scientists do not know where the virus resides between outbreaks, environmental control is impossible.
Ivermectin, the established
drug which successfully treats the infection, is known to be
effective against minor damage caused to the front of the eye by the worm, but until now scientists had very little clear evidence about the
drug's role in preventing more serious effects of infection, in particular damage to the optic nerve.
Parish says these positive results suggest the
drugs might be
effective against other autoimmune diseases such as multiple sclerosis.
In a study using mice, the researchers found that using Dox and TRAIL in the pseudo-platelet
drug delivery system was significantly more
effective against large tumors and circulating tumor cells than using Dox and TRAIL in a nano - gel delivery system without the platelet membrane.
The
drugs increased survival of mice infected with TB and were
effective against drug - resistant strains of TB.
Chemotherapy has been shown to be
effective in a wide range of patients, but one of its main problems is the emergence of resistance
against the anti-tumor
drug used.
«I hope the result will be
drugs that are more
effective against tuberculosis and offer a faster route to a cure with fewer side effects.»
«Since doxorubicin is one of the cheapest
drugs that is
effective against many types of cancer but rarely used in colon cancer, the combination therapy could be highly
effective in combating colon cancer while drastically lowering risk of cardiotoxic side effects.»
«Repurposed
drug found to be
effective against Zika virus: Researchers say findings support further investigation as potential treatment for Zika - infected adults.»
The
drug works by inhibiting replication of the hepatitis C virus; researchers noted that both hepatitis C and Zika belong to the same viral family and bore strong structural similarities that could make sofosbuvir
effective against the latter.